Bacterial agents and antibiotic sensitivity in children with urinary infection in two hospitals of Popayan, Colombia

Introduction: Urinary Tract Infection (UTI) is a common condition in children. Isolation of bacteria and early management is a priority in order to contribute to the reduction of morbidity and avoid bacterial resistance. Objectives: To identify bacterial etiologic agents and antibiotic sensitivity in children (1 month to 5 years of age) with UTI in two hospitals of Popayán, Colombia. Materials and methods: We conducted a cross-sectional study in children aged 1 month to 5 years of age who consulted the emergency services of two hospitals with clinical suspicion of UTI. The sample was 123 children. Using an instrument collected demographic variables, signs and symptoms, results of urinalysis, urine culture, sensitivity testing, treatment, and UTI classification. We determined the frequency and proportions of sociodemographic and clinical variables, bacterial agents and antibiotic resistance. Data was analyzed using SPSS 11.5 program. Results: We included 129 children diagnosed with UTI with positive urine culture, bladder catheter taken with 97.7% of cases. 74.8% of patients were female. Escherichia coli was the seed that was isolated more frequently (95.4%), then Sp Proteus (2.4%), and Klebsiella pneumoniae (1.6%). The antibiotics to which the bacteria showed adequate sensitivity were: ceftriaxone, amikacin, gentamicin, ciprofloxacin, nitrofurantoin, cefuroxime and cephalexin. Showed low sensitivity: ampicillin and trimethoprim sulfa. Conclusions: Escherichia coli was the bacteria that cause of UTI in our study population. For initial empiric treatment of hospitalized patients would recommend parenteral drug third generation cephalosporins (ceftriaxone) and aminoglycosides (amikacin, gentamicin). For outpatient management, oral antibiotics showed greater sensitivity were nalidixic acid, cefuroxime and cephalexin

Etiología bacteriana y sensibilidad antibiótica en niños con infección urinaria de dos centros hospitalarios de Popayán.

Introduction: Urinary Tract Infection (UTI) is a common condition in children. Isolation of bacteria and early management is a priority in order to contribute to the reduction of morbidity and avoid bacterial resistance. Objectives: To identify bacterial etiologic agents and antibiotic sensitivity in children (1 month to 5 years of age) with UTI in two hospitals of Popayán, Colombia. Materials and methods: We conducted a cross-sectional study in children aged 1 month to 5 years of age who consulted the emergency services of two hospitals with clinical suspicion of UTI. The sample was 123 children. Using an instrument collected demographic variables, signs and symptoms, results of urinalysis, urine culture, sensitivity testing, treatment, and UTI classification. We determined the frequency and proportions of sociodemographic and clinical variables, bacterial agents and antibiotic resistance. Data was analyzed using SPSS 11.5 program. Results: We included 129 children diagnosed with UTI with positive urine culture, bladder catheter taken with 97.7% of cases. 74.8% of patients were female. Escherichia coli was the seed that was isolated more frequently (95.4%), then Sp Proteus (2.4%), and Klebsiella pneumoniae (1.6%). The antibiotics to which the bacteria showed adequate sensitivity were: ceftriaxone, amikacin, gentamicin, ciprofloxacin, nitrofurantoin, cefuroxime and cephalexin. Showed low sensitivity: ampicillin and trimethoprim sulfa. Conclusions: Escherichia coli was the bacteria that cause of UTI in our study population. For initial empiric treatment of hospitalized patients would recommend parenteral drug third generation cephalosporins (ceftriaxone) and aminoglycosides (amikacin, gentamicin). For outpatient management, oral antibiotics showed greater sensitivity were nalidixic acid, cefuroxime and cephalexin.Introducción: La infección del Tracto Urinario (ITU) es una patología frecuente en la edad pediátrica. El aislamiento bacteriano y el manejo temprano con el medicamento apropiado son prioritarios para contribuir a la disminución de la morbilidad y evitar el incremento de la resistencia bacteriana. Objetivo: Identificar los agentes etiológicos bacterianos y su sensibilidad antibiótica en niños(as) de 1 mes a 5 años de edad con ITU, en dos instituciones de segundo y tercer nivel de la ciudad de Popayán. Materiales y métodos: Se llevó a cabo un estudio descriptivo de corte transversal en niños de 1 mes a 5 años de edad que consultaron a los servicios de urgencias de dos centros hospitalarios de Popayán, con sospecha clínica y paraclínica de infección urinaria. La muestra calculada resultante fue de 123 niños. Mediante un instrumento validado se recolectó variables demográficas, antecedentes, signos y síntomas, resultados de uroanálisis, urocultivo, antibiograma, tratamiento, clasificación de ITU y estudios complementarios. Se determinó la frecuencia y proporciones de las variables sociodemográficas y clínicas, de los agentes bacterianos y de la resistencia antibiótica. Se analizó la información por medio del programa SPSS versión 11.5. Resultados: Se incluyeron 129 niños con diagnóstico de ITU con urocultivo positivo, tomados con sonda vesical en 97.7% de los casos. 74.8% de los pacientes eran de género femenino. Escherichia coli fue el germen que se aisló con más frecuencia (95.4%), luego Proteus Sp. (2.4%), y Klebsiella pneumoniae (1.6%). Los antibióticos a los cuales los gérmenes presentaron mayor sensibilidad fueron: ceftriaxona, amikacina, gentamicina, ciprofloxacina, nitrofurantoina, cefuroxima y cefalexina. Mostraron baja sensibilidad ampicilina y el trimetoprim sulfa, Conclusiones: Escherichia coli fue la bacteria que más produjo infección urinaria en la población estudiada. Para el tratamiento empírico inicial de los pacientes hospitalizados, los medicamentos parenterales recomendados serian las cefalosporinas de tercera generación (ceftriaxona) y los aminoglicósidos (amikacina, gentamicina). Para el manejo ambulatorio, los antibióticos orales que mostraron mayor sensibilidad fueron ácido nalidíxico, cefuroxime y cefalexina

Bacterial agents and antibiotic sensitivity in children with urinary infection in two hospitals of Popayan, Colombia

Introduction: Urinary Tract Infection (UTI) is a common condition in children. Isolation of bacteria and early management is a priority in order to contribute to the reduction of morbidity and avoid bacterial resistance. Objectives: To identify bacterial etiologic agents and antibiotic sensitivity in children (1 month to 5 years of age) with UTI in two hospitals of Popayán, Colombia. Materials and methods: We conducted a cross-sectional study in children aged 1 month to 5 years of age who consulted the emergency services of two hospitals with clinical suspicion of UTI. The sample was 123 children. Using an instrument collected demographic variables, signs and symptoms, results of urinalysis, urine culture, sensitivity testing, treatment, and UTI classification. We determined the frequency and proportions of sociodemographic and clinical variables, bacterial agents and antibiotic resistance. Data was analyzed using SPSS 11.5 program. Results: We included 129 children diagnosed with UTI with positive urine culture, bladder catheter taken with 97.7% of cases. 74.8% of patients were female. Escherichia coli was the seed that was isolated more frequently (95.4%), then Sp Proteus (2.4%), and Klebsiella pneumoniae (1.6%). The antibiotics to which the bacteria showed adequate sensitivity were: ceftriaxone, amikacin, gentamicin, ciprofloxacin, nitrofurantoin, cefuroxime and cephalexin. Showed low sensitivity: ampicillin and trimethoprim sulfa. Conclusions: Escherichia coli was the bacteria that cause of UTI in our study population. For initial empiric treatment of hospitalized patients would recommend parenteral drug third generation cephalosporins (ceftriaxone) and aminoglycosides (amikacin, gentamicin). For outpatient management, oral antibiotics showed greater sensitivity were nalidixic acid, cefuroxime and cephalexin

Etiología bacteriana y sensibilidad antibiótica en niños con infección urinaria de dos centros hospitalarios de Popayán.

Introduction: Urinary Tract Infection (UTI) is a common condition in children. Isolation of bacteria and early management is a priority in order to contribute to the reduction of morbidity and avoid bacterial resistance. Objectives: To identify bacterial etiologic agents and antibiotic sensitivity in children (1 month to 5 years of age) with UTI in two hospitals of Popayán, Colombia. Materials and methods: We conducted a cross-sectional study in children aged 1 month to 5 years of age who consulted the emergency services of two hospitals with clinical suspicion of UTI. The sample was 123 children. Using an instrument collected demographic variables, signs and symptoms, results of urinalysis, urine culture, sensitivity testing, treatment, and UTI classification. We determined the frequency and proportions of sociodemographic and clinical variables, bacterial agents and antibiotic resistance. Data was analyzed using SPSS 11.5 program. Results: We included 129 children diagnosed with UTI with positive urine culture, bladder catheter taken with 97.7% of cases. 74.8% of patients were female. Escherichia coli was the seed that was isolated more frequently (95.4%), then Sp Proteus (2.4%), and Klebsiella pneumoniae (1.6%). The antibiotics to which the bacteria showed adequate sensitivity were: ceftriaxone, amikacin, gentamicin, ciprofloxacin, nitrofurantoin, cefuroxime and cephalexin. Showed low sensitivity: ampicillin and trimethoprim sulfa. Conclusions: Escherichia coli was the bacteria that cause of UTI in our study population. For initial empiric treatment of hospitalized patients would recommend parenteral drug third generation cephalosporins (ceftriaxone) and aminoglycosides (amikacin, gentamicin). For outpatient management, oral antibiotics showed greater sensitivity were nalidixic acid, cefuroxime and cephalexin.Introducción: La infección del Tracto Urinario (ITU) es una patología frecuente en la edad pediátrica. El aislamiento bacteriano y el manejo temprano con el medicamento apropiado son prioritarios para contribuir a la disminución de la morbilidad y evitar el incremento de la resistencia bacteriana. Objetivo: Identificar los agentes etiológicos bacterianos y su sensibilidad antibiótica en niños(as) de 1 mes a 5 años de edad con ITU, en dos instituciones de segundo y tercer nivel de la ciudad de Popayán. Materiales y métodos: Se llevó a cabo un estudio descriptivo de corte transversal en niños de 1 mes a 5 años de edad que consultaron a los servicios de urgencias de dos centros hospitalarios de Popayán, con sospecha clínica y paraclínica de infección urinaria. La muestra calculada resultante fue de 123 niños. Mediante un instrumento validado se recolectó variables demográficas, antecedentes, signos y síntomas, resultados de uroanálisis, urocultivo, antibiograma, tratamiento, clasificación de ITU y estudios complementarios. Se determinó la frecuencia y proporciones de las variables sociodemográficas y clínicas, de los agentes bacterianos y de la resistencia antibiótica. Se analizó la información por medio del programa SPSS versión 11.5. Resultados: Se incluyeron 129 niños con diagnóstico de ITU con urocultivo positivo, tomados con sonda vesical en 97.7% de los casos. 74.8% de los pacientes eran de género femenino. Escherichia coli fue el germen que se aisló con más frecuencia (95.4%), luego Proteus Sp. (2.4%), y Klebsiella pneumoniae (1.6%). Los antibióticos a los cuales los gérmenes presentaron mayor sensibilidad fueron: ceftriaxona, amikacina, gentamicina, ciprofloxacina, nitrofurantoina, cefuroxima y cefalexina. Mostraron baja sensibilidad ampicilina y el trimetoprim sulfa, Conclusiones: Escherichia coli fue la bacteria que más produjo infección urinaria en la población estudiada. Para el tratamiento empírico inicial de los pacientes hospitalizados, los medicamentos parenterales recomendados serian las cefalosporinas de tercera generación (ceftriaxona) y los aminoglicósidos (amikacina, gentamicina). Para el manejo ambulatorio, los antibióticos orales que mostraron mayor sensibilidad fueron ácido nalidíxico, cefuroxime y cefalexina