18 research outputs found
Supplementary Data 5 from Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death
p53 ChIPseq peaks from U2OS cells varying in p53 allelic status</p
Supplementary Table 1 from Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death
Summary of GOF vs. LOF activities of p53(A347D) in U2OS cells</p
Supplementary Data 1 from Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death
Differentially expressed genes in U2OS cells varying in p53 allelic status</p
Supplementary Table 2 from Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death
Characteristics of LFS patients' fibroblasts and derivatives</p
Supplementary Data 4 from Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death
p53 ChIPseq peaks from U2OS cells varying in p53 allelic status</p
Supplementary Data 2 from Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death
Differentially expressed genes in U2OS cells varying in p53 allelic status combined from two independent RNA library preparations</p
Supplementary Table S2 from p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression
Supplementary Table S2. List of antibodies and dilutions used in the study.</p
Supplementary Figure S6 from p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression
Supplementary Figure S6. Graphical abstract depicting the pro-metastatic role and mechanism of Trp53R172H-dependent Csf-1/Csf-1r signaling.</p
Supplementary Table S3 from p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression
Supplementary Table S3. Statistics of aligned reads from the CUT&RUN-seq analysis of H3K27ac in ESCC cells with Trp53R172H/- (n=3) and Trp53+/+ (n=2).</p
Supplementary Figure S4 from p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression
Supplementary Figure S4. Depletion of Brd4 reduces Csf1 secretion and ESCC tumor cell invasion.</p