Kragen v. Dist. Ct., 140 Nev. Adv. Op. 49 (Aug. 15, 2024)

The Nevada Court of Appeals held that, when evaluating appropriate home state jurisdiction in child custody disputes, the temporary or permanent nature of a child’s absence from the state must be assessed in light of the totality of the circumstances. By adopting the totality of the circumstances test, Nevada has fallen in line with a majority of states that have implemented the Uniform Child Custody Jurisdiction and Enforcement Act (“UCCJEA”)

[Re]Forming Public Space: A Critique of Hong Kong’s Park Governance through Architectural Intervention

This paper’s point of departure is a critique of the Hong Kong government’s somewhat rigid approach to regulating the public spaces of its parks. As an antidote to a rule-bound and somewhat restrictive set of policies, four groups of architecture students at the University of Hong Kong have designed various interventions for a public park in Hong Kong. The projects, entitled Pixel Wall, Fence Off, Border Mender, and Rocky present alternative ways of activating public space through architectural design

A faunal survey and zoogeographic analysis of the Curculionoidea (Coleoptera) (excluding Anthribidae, Platypodinae, and Scolytinae) of the Lower Rio Grande Valley of Texas

Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to [email protected], referencing the URI of the item.Includes bibliographical references: p. 239-257.Issued also on microfiche from Lange Micrographics.An annotated list of the Curculionoidea (Coleoptera) (excluding Anthribidae, Platypodinae, and Scolytinae) is presented for the Lower Rio Grande Valley (LRGV) of Texas. The list includes species that occur in Cameron, Hidalgo, Starr, and Willacy counties. Each of the 235 species in 97 genera is treated according to its geographical range, Lower Rio Grande distribution, seasonal activity, plant associations, and biology. The taxonomic arrangement follows O'Brien & Wibmer (1982). A table of the species occurring in particular areas of the Lower Rio Grande Valley, such as the Boca Chica Beach area, the Sabal Palm Grove Sanctuary, Bentsen-Rio Grande State Park, and the Falcon Dam area is included. A table of the species and their host associations is also presented. Genera (number of species in parentheses) with the largest number of species represented are: Anthoiionzits (12), Apion (13), Conotrachehts (II), Listronotils (17), Sibinia (10), and Siiticronyx (15). Thirty percent of the total species in the Lower Rio Grande Valley belong in these genera. There are 22 undetermined and/or undescribed species recorded. Zoogeographic comparisons are made between the LRGV and Guatemala, North Dakota, Victoria County, San Patricio County, Big Bend National Park, and southern Florida. A high percentage of species of the LRGV were found to have northern affinities. Eight non-native species were not included in the zoogeographic comparisons. Twelve species appear to be endemic to the LRGV. Fifty-seven percent of the 227 species analyzed have the LRGV as either their northern or southern boundary. our representative collecting sites in the LRGV were chosen to make comparisons. The greatest diversity of weevil species of the LRGV occurs in the Sabal Palm Grove Sanctuary (32%). This may be due to more extensive collecting at this site. Approximately one-third of the total diversity of the LRGV occurs on these 32 acres of land. Plant associations are known for 33% of the weevils occurring in the LRGV, although some of the associations may have been recorded from areas outside of the LRGV. Out of the 433 plant associations, 41.3% involve the families Fabaceae, Malvaceae, and Asteraceae

The Impact of Federal Regulation on Time to Equivalence and Compliance within the Orthopaedic Medical Device Industry

The Medical Device Amendments of 1976 (Public Law 94-295) consolidated and expanded existing federal authority over manufacturers of medical devices. This meant that any medical device manufactured after the Medical Device Amendment of 1976 needed to establish that it is substantially equivalent in terms of content, composition, intended use and related risk. This study was designed to investigate the influences on the process of notifying the Food and Drug Administration (FDA) of an orthopaedic medical device manufacturer\u27s intent to market a product. The study\u27s primary objectives were twofold: 1) determine the relationships of three independent variables (i.e., the company\u27s size and longevity) with the dependent variable, time to equivalence and 2) compare differences in mean days to equivalence based on specified company characteristics (i.e., regulatory affairs consultant use, regulatory training experiences, in-house regulatory department presence or absence, and attitudes toward influences on timely compliance). A survey instrument was returned by the regulatory manager at 39 companies representing 263 device equivalence submissions and 27 different medical device categories from 1977 through 1987. Four different statistical approaches were utilized: correlative-regressive, comparative, regressive-predictive, and distributive. From this research certain company characteristics which impact time to equivalence were identified. It was found that companies who have been manufacturing numerous years, manufacture more than one medical device, and use regulatory affairs professionals to assist with compliance issues, especially just following the enactment of a new regulation, may have predictably fewer days to equivalence than companies that do not possess these characteristics. Statistically significant relationships and differences in mean days to equivalence were computed for some variables

Exploration of latent space of LOD2 GML dataset to identify similar buildings

Explainable numerical representations of otherwise complex datasets are vital as they extract relevant information, which is more convenient to analyze and study. These latent representations help identify clusters and outliers and assess the similarity between data points. The 3-D model of buildings is one dataset that possesses inherent complexity given the variety in footprint shape, distinct roof types, walls, height, and volume. Traditionally, comparing building shapes requires matching their known properties and shape metrics with each other. However, this requires obtaining a plethora of such properties to calculate similarity. In contrast, this study utilizes an autoencoder-based method to compute the shape information in a fixed-size vector form that can be compared and grouped with the help of distance metrics. This study uses "FoldingNet," a 3D autoencoder, to generate the latent representation of each building from the obtained LOD2 GML dataset of German cities and villages. The Cosine distance is calculated for each latent vector to determine the locations of similar buildings in the city. Further, a set of geospatial tools is utilized to iteratively find the geographical clusters of buildings with similar forms. The state of Brandenburg in Germany is taken as an example to test the methodology. The study introduces a novel approach to finding similar buildings and their geographical location, which can define the neighborhood's character, history, and social setting. Further, the process can be scaled to include multiple settlements where more regional insights can be made.Comment: 10 pages, 6 figure

Hearing Others' Voices: An Exploration of the Musical Experiences of Immigrant Students Who Sing In High School Choir

The purpose of this study was to explore the musical experiences of immigrant students in an American high school choral classroom. This study revealed some of the central issues and tensions that immigrant students face as they are acculturated into secondary school music programs. The study explored the experiences of five immigrant female high school students who had emigrated from the following countries: Ecuador, El Salvador, Ghana, and Kazakhstan. The primary participants in the collective case study attended a suburban high school in the Mid-Atlantic region and had been living in the U.S. for three years or less. All participants were enrolled the same entry-level non-auditioned choral class. A survey was given to all choral students at the school which provided demographic information about the overall school choral program. Data collection methods included: semi-structured, in-depth interviews, student and teacher surveys, observations, focus groups, and dialogue journal writing collected over a ten-month period. Participants were encouraged to write journal entries in their native language. Lind's study of classroom environment and Gay's theory of culturally responsive teaching provided two important frameworks for analysis and interpretation of data. Data were coded through the NVivo software system for processing qualitative research. The data were analyzed and interpreted to create four narrative case studies. Findings suggested that the acculturation process for immigrant teenagers entails multiple dimensions with distinct outcomes depending on students' personal histories and educational backgrounds. Data revealed teacher dependence on contextual language in the choral classroom language as a vehicle for transfer of musical knowledge and that English language learners (ELL) are sometimes placed at a disadvantage in the choral classroom because of this reliance. Findings implied that some curricular norms in secondary choral classes such as vocal warm-ups, musical notation, sight reading requirements and choral festivals can be viewed as culturally incongruent with immigrants students' previous musical experiences. Data suggested that immigrant students in choral classes viewed the minimum requirements for participation in a school group, opportunities for public performance, and daily use of English in a non-threatening atmosphere as benefits of their overall high school education

Minding the Tragic Gap: Conversations of Invisibility in Early Childhood Music Education

During the last few decades, the music education profession has slowly begun to recognize the impact of music experiences in early childhood. Key publications in the 1970s drew attention to music education for young children (Greenberg 1976, Simons 1978, Zimmerman 1972). Articles focusing on young children\u27s musical development appeared in the 1980s (Hargreaves, 1986; Peery, Peery, & Draper, 1987; Sloboda, 1985; Swanick & Tillman, 1986). MENC (now the NationalAssociation for Music Education-NafME) began to address early childhood music education through focus days attached to biennial national conferences and through the establishment of the Early Childhood Special Research Interest Group. Yet in general, the music education profession lags behind other disciplines in recognizing the needs of young children. In this gap of recognition, young children remain an underrepresented population in the music. How do we change the perception of young children\u27s musical capabilities and abilities with parents, pre-service teachers, and colleagues

A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes

Myristoylation is a lipid modification involving the addition of a 14-carbon unsaturated fatty acid, myristic acid, to the N-terminal glycine of a subset of proteins, a modification that promotes their binding to cell membranes for varied biological functions. The process is catalyzed by myristoyl-CoA:protein N-myristoyltransferase (NMT), an enzyme which has been validated as a drug target in human cancers, and for infectious diseases caused by fungi, viruses and protozoan parasites. We purified Caenorhabditis elegans and Brugia malayi NMTs as active recombinant proteins and carried out kinetic analyses with their essential fatty acid donor, myristoyl-CoA and peptide substrates. Biochemical and structural analyses both revealed that the nematode enzymes are canonical NMTs, sharing a high degree of conservation with protozoan NMT enzymes. Inhibitory compounds that target NMT in protozoan species inhibited the nematode NMTs with IC50 values of 2.5-10 nM, and were active against B. malayi microfilariae and adult worms at 12.5 µM and 50 µM respectively, and C. elegans (25 µM) in culture. RNA interference and gene deletion in C. elegans further showed that NMT is essential for nematode viability. The effects observed are likely due to disruption of the function of several downstream target proteins. Potential substrates of NMT in B. malayi are predicted using bioinformatic analysis. Our genetic and chemical studies highlight the importance of myristoylation in the synthesis of functional proteins in nematodes and have shown for the first time that NMT is required for viability in parasitic nematodes. These results suggest that targeting NMT could be a valid approach for the development of chemotherapeutic agents against nematode diseases including filariasis