Additional file 1: of Paralog analyses reveal gene duplication events and genes under positive selection in Ixodes scapularis and other ixodid ticks

Title of data: Additional Notes, Figures and Tables. Description of data: Additional Notes, Figures and Tables. (DOCX 2395 kb

Difference in average touch error between low and high reward as a function of day relative to the day of the FUS.

<p>Responses to the cue are plotted in the left column. Responses to the target are plotted in the right column. Blue indicates group average (average low reward touch error—average high reward touch error) while red is the standard error of the mean. The numbers indicate the n value for that group. Asterisks above each average indicate a significant difference between the difference in reaction time on day 0 compared to the rest of the days (p < 0.05).</p

Average touch error to initial cue (left column), and to the correct target (right column).

<p>Blue indicates group average while red is the 95% confidence interval for the mean. There was a significant difference touch error to the cue on day 0 and the majority of the rest of the days (p < 0.05). There was a significant difference touch error to the correct on day 0 and some of the other days (p < 0.05). The numbers above each average indicate the n value for that group. The horizontal bar indicates baseline reaction time.</p

Average reaction time to initial cue (left column), and to the correct target (right column).

<p>Blue indicates group average while red is the 95% confidence interval for the mean. For all NHP there is a significant increase in reaction time on day 0 compared to the rest of the days (p < 0.05). The numbers above each average indicate the n value for that group. The horizontal bar indicates baseline reaction time.</p

Random dot motion and reward magnitude bias task.

<p>Cues appear in the center of the left or right side of the screen randomly. Once the initial cue is touched three new stimuli appear: A correct target appears on either the inside (towards the middle of the screen) or the outside (towards the edge of the screen) on the same side the intial cue, and a distractor target will appear opposing the correct target as well as moving dots will appear where the initial cue was. Horizontal and vertical bars indicate high and low reward respectively. Reward magnitude is random so subjects cannot predict reward order.</p

Dot coherence percentages for 80% accuracy.

<p>Table is divided into days relative to the FUS with MB procedure, animal and the direction of the moving dots.</p><p>Dot coherence percentages for 80% accuracy.</p

Difference in average touch error between ipsilateral and contralateral hands as a function of day relative to the day of the FUS procedure.

<p>Responses to the cue are plotted in the left column. Responses to the target are plotted in the right column. Blue indicates group average (average ipsilateral hand touch error—average contralateral hand touch error) while red is the standard error of the mean. The numbers indicate the n value for that group. Asterisks above each average indicate a significant difference between the difference in reaction time on day 0 compared to the rest of the days (p < 0.05).</p

Volume of BBB opening per NHP and location.

<p>Table shows the BBB opening volume per target location, animal and pressure.</p><p>Volume of BBB opening per NHP and location.</p

Contrast Enhanced BBB opening.

<p>The blue region shows a 10% increase in contrast over the background. A) Opening in the putamen of A. B) Opening in the caudate and putamen of N. C) Opening in the putamen of Ob. D) Opening in the caudate of O</p

Raw reaction time and touch error to initial cue (left column), and to the correct target (right column).

<p>Blue diamonds indicate raw reaction time in seconds to either the initial cue or correct target. Red asterisks indicate raw touch error to either the initial cue or correct target. Reaction time is plotted on the left vertical axis while touch error is plotted on the right vertical axis. Dashed vertical lines indicate days when the FUS with MB procedure occurred.</p