2 research outputs found
Dataset 29-2018
<p><b>High prevalence of respiratory virus and
atypical bacterium among children with a probable diagnosis of pertussis</b></p>
<p> </p>
<p>Jorge Valverde<sup>1<b>†</b></sup>, Stephanie Saiki<sup>2<b>†</b></sup>,
Angela Cornejo-Tapia<sup>1<b>*</b></sup>,
Fernando Vásquez-Achaya<sup>1</sup>, Maria Esther Castillo<sup>3</sup>, Verónica
Petrozzi-Helasvuo<sup>1</sup>, Wilmer Silva-caso<sup>1</sup>, Miguel Angel
Aguilar-Luis<sup>1,2,4</sup>, Olguita del Aguila<sup>5</sup>, Carlos Bada<sup>6</sup>,
Erico Cieza-Mora<sup>7</sup>, Juana del Valle-Mendoza<sup>1,2<b>*</b></sup></p><p><sup><b><br></b></sup></p><p><sup><b><br></b></sup></p><p></p><p><b>ABSTRACT</b></p>
<p><b>Background:
</b>Acute respiratory infections (ARIs) represent an important cause of
morbidity and mortality in children, remaining a major public health concern,
especially affecting children under 5 years old from low-income countries.
Unfortunately, information regarding their epidemiology is still limited in
Peru</p>
<p><b>Methods:</b> A secondary data
analysis was performed from a previous cross-sectional study conducted in
children with a probable diagnosis of Pertussis from January 2010 to July 2012.
All samples were analyzed via Polymerase Chain Reaction (PCR) for the following
etiologies: Influenza-A, Influenza-B, RSV-A, RSV-B, Adenovirus, Parainfluenza 1
virus, Parainfluenza 2 virus, Parainfluenza 3 virus, <i>Mycoplasma pneumoniae</i> and <i>Chlamydia
pneumoniae</i>.</p>
<p><b>Results:</b> A total
of 288 patients were included. The most common pathogen isolated was Adenovirus
(49%), followed by <i>Bordetella pertussis</i>
(41%) from our previous investigation, the most prevelant microorganisms were <i>Mycoplasma pneumonia</i> (26%) and
Influenza-B (19.8%). Coinfections were reported in 53.5% of samples and the
most common association was found between <i>M.
pneumoniae</i> and Adenovirus (9%). <b>Conclusions:</b>
There was a high prevalence of Adenovirus, <i>Mycoplasma pneumoniae</i> and other etiologies
in patients with a probable diagnosis of pertussis. Despite the presence of persistent cough
lasting at least two weeks and other clinical
characteristics highly suspicious of pertussis, secondary etiologies
should be considered in children under 5 years-old in order to give a proper treatment.</p><sup><b></b></sup><p></p
Dataset 2018
High prevalence of respiratory virus and atypical bacterium among children with a probable diagnosis of pertussis<div>
<p> </p>
<p>Jorge Valverde<sup>1<b>†</b></sup>,
Stephanie Saiki<sup>2<b>†</b></sup>, Angela
Cornejo-Tapia<sup>1<b>*</b></sup>, Fernando
Vásquez-Achaya<sup>1</sup>, Maria Esther Castillo<sup>3</sup>, Verónica
Petrozzi-Helasvuo<sup>1</sup>, Wilmer Silva-caso<sup>1</sup>, Miguel Angel
Aguilar-Luis<sup>1,2,4</sup>, Olguita del Aguila<sup>5</sup>, Carlos Bada<sup>6</sup>,
Erico Cieza-Mora<sup>7</sup>, Juana del Valle-Mendoza<sup>1,2<b>*</b></sup></p><div><br></div><div><p><b>Background: </b>Acute respiratory infections (ARIs) represent an
important cause of morbidity and mortality in children, remaining a major
public health concern, especially affecting children under 5 years old from
low-income countries. Unfortunately, information regarding their epidemiology
is still limited in Peru</p>
<p><b>Methods:</b> A
secondary data analysis was performed from a previous cross-sectional study conducted
in children with a probable diagnosis of Pertussis from January 2010 to July
2012. All samples were analyzed via Polymerase Chain Reaction (PCR) for the
following etiologies: Influenza-A, Influenza-B, RSV-A, RSV-B, Adenovirus,
Parainfluenza 1 virus, Parainfluenza 2 virus, Parainfluenza 3 virus, <i>Mycoplasma pneumoniae</i> and <i>Chlamydia pneumoniae</i>.</p>
<p><b>Results:</b> A total
of 288 patients were included. The most common pathogen isolated was Adenovirus
(49%), followed by <i>Bordetella pertussis</i>
(41%) from our previous investigation, the most prevelant microorganisms were <i>Mycoplasma pneumonia</i> (26%) and
Influenza-B (19.8%). Coinfections were reported in 53.5% of samples and the
most common association was found between <i>M.
pneumoniae</i> and Adenovirus (9%). <b>Conclusions:</b>
There was a high prevalence of Adenovirus, <i>Mycoplasma pneumoniae</i> and other etiologies
in patients with a probable diagnosis of pertussis. Despite the presence of persistent cough
lasting at least two weeks and other clinical
characteristics highly suspicious of pertussis, secondary etiologies
should be considered in children under 5 years-old in order to give a proper treatment.</p><br></div></div