Meta-analysis exploring the effect of 29/29 poly-Q repeats on risk of BC in BRCA1/2, BRCA1, and BRCA2 mutation carriers.

<p>Meta-analysis exploring the effect of 29/29 poly-Q repeats on risk of BC in BRCA1/2, BRCA1, and BRCA2 mutation carriers.</p

Items used in quality scoring for studies of the association between polymorphic repeat length in the AIB1 gene and breast cancer risk in BRCA1 and BRCA2 mutation carriers.

a<p>If compliance is not specifically indicated in the text, non compliance is assumed.</p

Study selection process and reasons for exclusion of studies.

<p>Study selection process and reasons for exclusion of studies.</p

Characteristics of observational studies of the relation between polymorphic repeat length in the AIB1 gene and breast cancer risk in BRCA1 and BRCA2 mutation carriers included in the meta-analysis.

*<p>BMI: body mass index.</p

Clinical characteristics of 569 study subjects (sample 1) and of 852 study subjects (sample 2) according to the SNP rs35767 near IGF1.

<p>Data are means ± SD. Differences of continuous variables between groups were tested after adjusting for age, gender, and BMI by ANCOVA (general linear model). Categorical variables were compared by χ² test. § <i>P</i> values refer to results after analyses with adjustment for gender. #<i>P</i> values refer to results after analyses with adjustment for age, and gender using a general linear model. *<i>P</i> values refer to results after analyses with adjustment for age, gender and BMI using a general linear model. Effect sizes (β and SE) per allele A and corresponding <i>P</i> values are shown.</p