53 research outputs found

    Statistical Fracture Modeling: Crack Path and Fracture Criteria With Application to Homogeneous and Functionally Graded Materials

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    Analysis has been performed onfractu# initiation near a crack in a brittle material with strength described by Weibu# statistics. This nonlocal fractul model allows for a direct correlation between near crack-tip stresses and failuz# Predictions are made for both thetou)((') and average fractub initiation angle of a crack uack mixed-mode loading. This is pertinent for composites and is especially interesting forfufiGzYYb-)j graded materials (FGMs), where the stress and strength fields vary from thehomogeneou form away from the crack tip. Both analytic and finite element analyses of FGMs reveal that gradients inWeibuI scaling stress r 0 yubu(b lead to a dramatic decrease of initiationfractut toutionb moreover, gradients normal to the crack resub in a crack growing toward the weaker material. When comparing FGMs with gradients inYouYG( moduG( in the direction of the crack path, Ex, and the same stress-intensity factor K, the crack growing into the steeper negative gradient will betouz)jfi if m, theWeibufi moduufi is low; with growth in the sti# direction, the e#ect is opposite. These e#ects o#set the higher-stress intensity for cracks growing into more compliant material, and the crack-tip shielding when growing into a sti#er material baseduse expectations for the applied load. Perpendicu-G gradients inmoduj# cancaufi a far-field mode I loading toproduY mixed-mode loading of the crack tip and other asymmetric adjuetricb in the stress field; the gradientinduen non-coplanar cracking that depends strongly on m

    Pain perception and brain evoked potentials in patients with angina despite normal coronary angiograms.

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    OBJECTIVE: To evaluate the role of nociception in patients with angina despite normal coronary angiograms and to investigate whether any abnormality is confined to visceral or somatosensory perception. METHODS: Perception, pain threshold, and brain evoked potentials to nociceptive electrical stimuli of the oesophageal mucosa and the sternal skin were investigated in 10 patients who had angina but normal coronary angiograms, no other signs of cardiac disease, and normal upper endoscopy. Controls were 10 healthy volunteers. The peaks of the evoked potential signal were designated N for negative deflections and P for positive. Numbers were given to the peaks in order of appearance after the stimulus. The peak to peak amplitudes (P1/N1, N1/P2) were measured in microV. RESULTS: (1) Angina pectoris was provoked in seven patients following continuous oesophageal stimulation. (2) Distant projection of pain occurred after continuous electrical stimulation of the oesophagus in four patients and in no controls. (3) Patients had higher oesophageal pain thresholds (median 16.3 mA v 7.3 mA, P = 0.02) to repeated stimuli than controls, whereas the values did not differ with respect to the skin. There were no intergroup differences in thresholds to single stimuli. (4) Patients had substantially reduced brain evoked potential amplitudes after both single oesophageal (P1/N1, median values: 7.2 microV, controls: 29.0 microV; N1/P2: 16.5 microV, controls: 66.0 microV; P < 0.001 for both) and skin (N1/P2: 13.5 microV; controls: 76.0 microV; P < 0.001) stimuli despite the similar pain thresholds. CONCLUSION: Central nervous system responses to visceral and somatosensory nociceptive input are altered in patients who have angina despite normal coronary angiograms
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