366 research outputs found
Role of FKBP51 in the modulation of the expression of the corticosteroid receptors in bovine thymus following glucocorticoid administration
Coping with tissue sampling in suboptimal conditions: Comparison of different tissue preservation methods for histological and molecular analysis
Ninja data analysis with a detection pipeline based on the Hilbert-Huang Transform
The Ninja data analysis challenge allowed the study of the sensitivity of
data analysis pipelines to binary black hole numerical relativity waveforms in
simulated Gaussian noise at the design level of the LIGO observatory and the
VIRGO observatory. We analyzed NINJA data with a pipeline based on the Hilbert
Huang Transform, utilizing a detection stage and a characterization stage:
detection is performed by triggering on excess instantaneous power,
characterization is performed by displaying the kernel density enhanced (KD)
time-frequency trace of the signal. Using the simulated data based on the two
LIGO detectors, we were able to detect 77 signals out of 126 above SNR 5 in
coincidence, with 43 missed events characterized by signal to noise ratio SNR
less than 10. Characterization of the detected signals revealed the merger part
of the waveform in high time and frequency resolution, free from time-frequency
uncertainty. We estimated the timelag of the signals between the detectors
based on the optimal overlap of the individual KD time-frequency maps, yielding
estimates accurate within a fraction of a millisecond for half of the events. A
coherent addition of the data sets according to the estimated timelag
eventually was used in a characterization of the event.Comment: Accepted for publication in CQG, special issue NRDA proceedings 200
Tissue and species identification in minced meat and meat products from italian commercial markets by dna microarray and histological approach
Prethymic cytoplasmic CD3 negative acute lymphoblastic leukemia or acute undifferentiated leukemia: a case report
Acute undiffentiated leukemia (AUL) is an acute leukemia with no more than one membrane marker of any given lineage. Blasts often express HLA-DR, CD34, and/or CD38 and may be positive for terminal deoxynucleotidyl transferase (TdT). The expression of CD34, HLA-DR, and CD38 has been shown in pro-T-ALL, although in this case, blasts should also express CD7 and cyCD3. However, some cases of T-ALL without CD3 in the cytoplasm and all TCR chain genes in germ line configuration are reported, features that fit well with a very early hematopoietic cell. We report a case of acute leukemia CD34+/-HLADR+CD7+CD38+cyCD3- in which a diagnosis of AUL was considered. However the blasts were also positive for CD99 and TCR delta gene rearrangement which was found on molecular studies. Therefore a differential diagnosis between AUL and an early cyCD3 negative T-ALL was debated
Anti-Kasha Conformational Photoisomerization of a Heteroleptic Dithiolene Metal Complex Revealed by Ultrafast Spectroscopy
We investigated the anti-Kasha photochemistry and anti-Kasha emission of d8-metal donor-acceptor dithiolene with femtosecond UV-vis transient absorption spectroscopy and molecular modeling. Experimentally, we found a lifetime of 1.4 ps for higher excited states, which is exceptionally long when compared to typical values for internal conversion (IC) (10 s of fs or less). Consequently, a substantial emission originates from the second excited state. Molecular modeling suggests this to be a consequence of the spatially separated molecular orbitals of the first and second excited states, which gives a charge transfer character to the IC. More surprisingly, we found that the inherent flexibility of the molecule allows the metal complex to access different configurations depending on the photoexcited state. We believe that this unique manifestation of anti-Kasha photoinduced conformational isomerization is facilitated by the exceptionally long lifetime of the second excited state
Isoelectronic series of oxygen deficient centers in silica: experimental estimation of homogeneous and inhomogeneous spectral widths
We report nanosecond time-resolved photoluminescence measurements on the
isoelectronic series of oxygen deficient centers in amorphous silica,
Si-ODC(II), Ge-ODC(II) and Sn-ODC(II) which are responsible of fluorescence
activities at 4 eV under excitation at 5 eV. The dependence of the
first moment of their emission band on time, and that of the radiative decay
lifetime on emission energy are analyzed within a theoretical model able to
describe the effects introduced by disorder on the optical properties of the
defects. We obtain separate estimates of the homogeneous and inhomogeneous
contributions to the measured emission linewidth and we derive homogeneous
spectroscopic features of the investigated point defects (Huangh-Rhys factor,
homogeneous width, oscillator strength, vibrational frequency). The results
point to a picture in which an oxygen deficient center localized on a heavier
atom features a higher degree of inhomogeneity due to stronger local distortion
of the surrounding matrix. For Si, Ge, Sn related defects the parameter
, able to quantify inhomogeneity, results to be 65, 78 and 90$%,
respectively
The impact of viscosity on the morphology of gaseous flows in semidetached binary systems
Results of 3D gas dynamical simulation of mass transfer in binaries are
presented for systems with various values of viscosity. Analysis of obtained
solutions shows that in the systems with low value of viscosity the flow
structure is qualitatively similar to one for systems with high viscosity.
Presented calculations confirm that there is no shock interaction between the
stream from L1 and the forming accretion disk (`hot spot') at any value of
viscosity.Comment: LaTeX, 18 pages, 15 eps-figures, Astron. Reports, in pres
Magnetic Field Limitations on Advection Dominated Flows
Recent papers discussing advection dominated accretion flows (ADAF) as a
solution for astrophysical accretion problems should be treated with some
caution because of their uncertain physical basis. The suggestions underlying
ADAF involve ignoring the magnetic field reconnection in heating of the plasma
flow, assuming electron heating due only to binary Coulomb collisions with
ions. Here, we analyze the physical processes in optically thin accretion flows
at low accretion rates including the influence of an equipartition turbulent
magnetic field. For these conditions there is continuous destruction of
magnetic flux by reconnection.
The reconnection is expected to significantly heat the electrons which can
efficiently emit magnetobremstrahlung radiation. Because of this electron
emission, the radiative efficiency of the ADAF is not small. We suggest that
the small luminosities of nearby galactic black holes is due to outflows rather
than ADAF accretion.Comment: 7 pages, 3 figures, Submitted to Ap
Swift BAT Survey of AGN
We present the results of the analysis of the first 9 months of data of the
Swift BAT survey of AGN in the 14-195 keV band. Using archival X-ray data or
follow-up Swift XRT observations, we have identified 129 (103 AGN) of 130
objects detected at |b|> 15 deg and with significance >4.8 sigma. One source
remains unidentified. These same X-ray data have allowed measurement of the
X-ray properties of the objects. We fit a power law to the log N - log S
distribution, and find the slope to be 1.42+/-0.14. Characterizing the
differential luminosity function data as a broken power law, we find a break
luminosity log L_*(erg/s) = 43.85+/-0.26, a low luminosity power law slope
a=0.84^{+0.16}_{-0.22}, and a high luminosity power law slope
b=2.55^{+0.43}_{-0.30}, similar to the values that have been reported based on
INTEGRAL data. We obtain a mean photon index 1.98 in the 14-195 keV band, with
an rms spread of 0.27. Integration of our luminosity function gives a local
volume density of AGN above 10^{41} erg/s of 2.4x10^{-3}/Mpc^3, which is about
10% of the total luminous local galaxy density above M_*=-19.75. We have
obtained X-ray spectra from the literature and from Swift XRT follow-up
observations. These show that the distribution of log n_H is essentially flat
from n_H=10^{20}/cm^{2} to 10^{24}/cm^2, with 50% of the objects having column
densities of less than 10^{22}/cm^{2}. BAT Seyfert galaxies have a median
redshift of 0.03, a maximum log luminosity of 45.1, and approximately half have
log n_H > 22.Comment: 15 pages, 15 figures, 2 tables; to appear in the Astrophysical
Journal, July 10, 2008, v. 68
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