218 research outputs found
Vibrating Winding Branes, Wrapping Democracy and Stabilization of Extra Dimensions in Dilaton Gravity
We show that, in the context of dilaton gravity, a recently proposed
democratic principle for intersection possibilities of branes winding around
extra dimensions yield stabilization, even with the inclusion of momentum modes
of the wrapped branes on top of the winding modes. The constraints for
stabilization massaged by string theory inputs forces the number of observed
dimensions to be three. We also discuss consequences of adding ordinary matter
living in the observed dimensions.Comment: Added a section discussing the linear and non-linear stability of the
equilibrium point of the scale factors of the extra dimensions. Corrected a
typo in the original field equations and other typos. Added and changed
references. Final version appeared in JHE
T and S dualities and The cosmological evolution of the dilaton and the scale factors
Cosmologically stabilizing radion along with the dilaton is one of the major
concerns of low energy string theory. One can hope that T and S dualities can
provide a plausible answer. In this work we study the impact of S and T duality
invariances on dilaton gravity. We have shown various instances where
physically interesting models arise as a result of imposing the mentioned
invariances. In particular S duality has a very privileged effect in that the
dilaton equations partially decouple from the evolution of the scale factors.
This makes it easy to understand the general rules for the stabilization of the
dilaton. We also show that certain T duality invariant actions become S duality
invariance compatible. That is they mimic S duality when extra dimensions
stabilize.Comment: Corrected a misleading interpretation of the S duality transformation
and a wrong comment on d=10. I thank A.Kaya for pointing this out to me in
time. So the new version is dealing with d=10 only. Added references and
corrected some typos. Minor re-editing. Omitted a section for elaboration in
a further study. Corrected further typo
Fluctuations of an evaporating black hole from back reaction of its Hawking radiation: Questioning a premise in earlier work
This paper delineates the first steps in a systematic quantitative study of
the spacetime fluctuations induced by quantum fields in an evaporating black
hole. We explain how the stochastic gravity formalism can be a useful tool for
that purpose within a low-energy effective field theory approach to quantum
gravity. As an explicit example we apply it to the study of the
spherically-symmetric sector of metric perturbations around an evaporating
black hole background geometry. For macroscopic black holes we find that those
fluctuations grow and eventually become important when considering sufficiently
long periods of time (of the order of the evaporation time), but well before
the Planckian regime is reached. In addition, the assumption of a simple
correlation between the fluctuations of the energy flux crossing the horizon
and far from it, which was made in earlier work on spherically-symmetric
induced fluctuations, is carefully analyzed and found to be invalid. Our
analysis suggests the existence of an infinite amplitude for the fluctuations
of the horizon as a three-dimensional hypersurface. We emphasize the need for
understanding and designing operational ways of probing quantum metric
fluctuations near the horizon and extracting physically meaningful information.Comment: 10 pages, REVTeX; minor changes, a few references added and a brief
discussion of their relevance included. To appear in the proceedings of the
10th Peyresq meeting. Dedicated to Rafael Sorkin on the occasion of his 60th
birthda
Bimodal Expansion of the Lymphatic Vessels Is Regulated by the Sequential Expression of IL-7 and Lymphotoxin α1β2 in Newly Formed Tertiary Lymphoid Structures.
Lymphangiogenesis associated with tertiary lymphoid structure (TLS) has been reported in numerous studies. However, the kinetics and dynamic changes occurring to the lymphatic vascular network during TLS development have not been studied. Using a viral-induced, resolving model of TLS formation in the salivary glands of adult mice we demonstrate that the expansion of the lymphatic vascular network is tightly regulated. Lymphatic vessel expansion occurs in two distinct phases. The first wave of expansion is dependent on IL-7. The second phase, responsible for leukocyte exit from the glands, is regulated by lymphotoxin (LT)βR signaling. These findings, while highlighting the tight regulation of the lymphatic response to inflammation, suggest that targeting the LTα1β2/LTβR pathway in TLS-associated pathologies might impair a natural proresolving mechanism for lymphocyte exit from the tissues and account for the failure of therapeutic strategies that target these molecules in diseases such as rheumatoid arthritis
Particle creation, classicality and related issues in quantum field theory: II. Examples from field theory
We adopt the general formalism, which was developed in Paper I
(arXiv:0708.1233) to analyze the evolution of a quantized time-dependent
oscillator, to address several questions in the context of quantum field theory
in time dependent external backgrounds. In particular, we study the question of
emergence of classicality in terms of the phase space evolution and its
relation to particle production, and clarify some conceptual issues. We
consider a quantized scalar field evolving in a constant electric field and in
FRW spacetimes which illustrate the two extreme cases of late time adiabatic
and highly non-adiabatic evolution. Using the time-dependent generalizations of
various quantities like particle number density, effective Lagrangian etc.
introduced in Paper I, we contrast the evolution in these two limits bringing
out key differences between the Schwinger effect and evolution in the de Sitter
background. Further, our examples suggest that the notion of classicality is
multifaceted and any one single criterion may not have universal applicability.
For example, the peaking of the phase space Wigner distribution on the
classical trajectory \emph{alone} does not imply transition to classical
behavior. An analysis of the behavior of the \emph{classicality parameter},
which was introduced in Paper I, leads to the conclusion that strong particle
production is necessary for the quantum state to become highly correlated in
phase space at late times.Comment: RevTeX 4; 27 pages; 18 figures; second of a series of two papers, the
first being arXiv:0708.1233 [gr-qc]; high resolution figures available from
the authors on reques
Particle creation, classicality and related issues in quantum field theory: I. Formalism and toy models
The quantum theory of a harmonic oscillator with a time dependent frequency
arises in several important physical problems, especially in the study of
quantum field theory in an external background. While the mathematics of this
system is straightforward, several conceptual issues arise in such a study. We
present a general formalism to address some of the conceptual issues like the
emergence of classicality, definition of particle content, back reaction etc.
In particular, we parametrize the wave function in terms of a complex number
(which we call excitation parameter) and express all physically relevant
quantities in terms it. Many of the notions -- like those of particle number
density, effective Lagrangian etc., which are usually defined using asymptotic
in-out states -- are generalized as time-dependent concepts and we show that
these generalized definitions lead to useful and reasonable results. Having
developed the general formalism we apply it to several examples. Exact analytic
expressions are found for a particular toy model and approximate analytic
solutions are obtained in the extreme cases of adiabatic and highly
non-adiabatic evolution. We then work out the exact results numerically for a
variety of models and compare them with the analytic results and
approximations. The formalism is useful in addressing the question of emergence
of classicality of the quantum state, its relation to particle production and
to clarify several conceptual issues related to this. In Paper II
(arXiv:0708.1237), which is a sequel to this, the formalism will be applied to
analyze the corresponding issues in the context of quantum field theory in
background cosmological models and electric fields.Comment: RevTeX 4; 32 pages; 28 figures; first of a series of two papers, the
second being arXiv:0708.1237 [gr-qc]; high resolution figures available from
the authors on reques
Fibroblastic reticular cells provide a supportive niche for lymph node–resident macrophages
The lymph node (LN) is home to resident macrophage populations that are essential for immune function and homeostasis, but key factors controlling this niche are undefined. Here, we show that fibroblastic reticular cells (FRCs) are an essential component of the LN macrophage niche. Genetic ablation of FRCs caused rapid loss of macrophages and monocytes from LNs across two in vivo models. Macrophages co‐localized with FRCs in human LNs, and murine single‐cell RNA‐sequencing revealed that FRC subsets broadly expressed master macrophage regulator CSF1. Functional assays containing purified FRCs and monocytes showed that CSF1R signaling was sufficient to support macrophage development. These effects were conserved between mouse and human systems. These data indicate an important role for FRCs in maintaining the LN parenchymal macrophage niche
Multiorder coherent Raman scattering of a quantum probe field
We study the multiorder coherent Raman scattering of a quantum probe field in
a far-off-resonance medium with a prepared coherence. Under the conditions of
negligible dispersion and limited bandwidth, we derive a Bessel-function
solution for the sideband field operators. We analytically and numerically
calculate various quantum statistical characteristics of the sideband fields.
We show that the multiorder coherent Raman process can replicate the
statistical properties of a single-mode quantum probe field into a broad comb
of generated Raman sidebands. We also study the mixing and modulation of photon
statistical properties in the case of two-mode input. We show that the prepared
Raman coherence and the medium length can be used as control parameters to
switch a sideband field from one type of photon statistics to another type, or
from a non-squeezed state to a squeezed state and vice versa.Comment: 12 pages, 7 figures, to be published in Phys. Rev.
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