Excerpts

Commencement address given by Alan K. Campbell, Director of U. S. Office of Personnel Management, to the Summer 1979 graduating class of The Ohio State University, St. John Arena, Columbus, Ohio, August 30, 1979

The Negro in Syracuse: His Education, Employment, Income and Housing

One of the high functions of social science scholarship is to provide factual and soundly analytical basis for intelligent social action. As Syracuse and Onondaga County continue to work at the resolution of racial conflicts over the months and years ahead, men of good will shall need as accurate and as unemotional a portrait as possible of the basic dimensions of the race problem in this area. With this in mind, a number of scholars, mostly from the Maxwell Graduate School of Citizenship and Public Affairs at Syracuse University, but including representatives from the College of Business and the College of Law, came together in late 1963 to volunteer time and energy in the preparation of an objective report of the Negro situation in the Syracuse area. - Prefac

Norman Julius Zabusky OBITUARY

Norman Julius Zabusky, who laid the foundations for several critical advancements in nonlinear science and experimental mathematics, died of idiopathic pulmonary fibrosis on 5 February 2018 in Beersheba, Israel. He also made fundamental contributions to computational fluid dynamics and advocated the importance of visualization in science.Published versio

City Budgets and the Black Constituency

The fiscal crisis of American cities is related to the existence of a relatively large black population. To examine this issue, as well as others, a sample has been selected from the 37 largest central cities and divided into two groups: one composed of cities with a majority or near-majority black population, the other overwhelmingly white in its ethnic composition. Certain social and economic characteristics of both sets of cities are then related to the magnitude of their public expenditures and the characteristics of the resource base from which part of the resources must be drawn to support these expenditure levels

The Metropolitan Economy of New York: Distribution of Economic Activity and the Governmental System

This paper surveys the current pattern of growth of the New York City economy and the present pattern of economic decentralization within the New York metropolitan region. Then it assesses what these patterns mean to the City\u27s fiscal position. We consider first the anatomy of growth in the city and region and turn then to its implications for the City\u27s taxable capacity. Having generally characterized the tax base response to these growth patterns, we examine the adequacy of the City\u27s fiscal and governmental system to cope with concurrent pressures for increased public policy alternatives to resolving, or partially resolving, the City\u27s fiscal ills

Intergovernmental and Functional Aspects of Public Employment Trends in the United States

There is a great deal of policy concern over the issue of employment and compensation levels in the public sector. This concern covers topics ranging from rising direct labor costs and pension benefits, to the unbalanced growth of central city government and other service sector employment, to power inequality in collective bargaining, to the lack of incentive for productivity improvement. While there have been substantive case studies which have made effective use of local data to deal with certain of these issues, aggregate work on the trends in state-local government public employment has been less satisfactory. Any analysis of state and local government employment problems on an aggregate basis depends on the extent and quality of data available. In this context, this article will undertake two tasks: a description of the trends in public employment, and an assessment of the value and comparability of those data which are presently available

Protein Kinase A Activity and Anchoring Are Required for Ovarian Cancer Cell Migration and Invasion

Epithelial ovarian cancer (EOC) is the deadliest of the gynecological malignancies, due in part to its clinically occult metastasis. Therefore, understanding the mechanisms governing EOC dissemination and invasion may provide new targets for antimetastatic therapies or new methods for detection of metastatic disease. The cAMP-dependent protein kinase (PKA) is often dysregulated in EOC. Furthermore, PKA activity and subcellular localization by A-kinase anchoring proteins (AKAPs) are important regulators of cytoskeletal dynamics and cell migration. Thus, we sought to study the role of PKA and AKAP function in both EOC cell migration and invasion. Using the plasma membrane-directed PKA biosensor, pmAKAR3, and an improved migration/invasion assay, we show that PKA is activated at the leading edge of migrating SKOV-3 EOC cells, and that inhibition of PKA activity blocks SKOV-3 cell migration. Furthermore, we show that while the PKA activity within the leading edge of these cells is mediated by anchoring of type-II regulatory PKA subunits (RII), inhibition of anchoring of either RI or RII PKA subunits blocks cell migration. Importantly, we also show – for the first time – that PKA activity is up-regulated at the leading edge of SKOV-3 cells during invasion of a three-dimensional extracellular matrix and, as seen for migration, inhibition of either PKA activity or AKAP-mediated PKA anchoring blocks matrix invasion. These data are the first to demonstrate that the invasion of extracellular matrix by cancer cells elicits activation of PKA within the invasive leading edge and that both PKA activity and anchoring are required for matrix invasion. These observations suggest a role for PKA and AKAP activity in EOC metastasis

Signal Processing

Contains research objectives and reports on two research projects.Joint Services Electronics Programs (U. S. Army, U. S. Navy, and U. S. Air Force) under Contract DA 28-043-AMC-02536(E