High-speed Developments in Avian Genomics

Until recently, definitions of avian genome structure and function were based solely on our knowledge of the chicken genome. The expansion of genomic studies to include nonmodel avian species allows us not only to refine those definitions but also to begin collecting the necessary resources to initiate a truly ecological genomics of birds. In this article we review new genomic technologies that will speed up the investigation of avian genome function. The streamlined nature of avian genomes implies that large-scale transcriptional analyses, studies of the role of regulatory elements and of developmental genes, and even the annotation of avian genomes will yield interesting surprises. We review promising methods used to investigate genome evolution in birds as well as the means by which to integrate functional genomics approaches and transcriptional profiling information into ecological and evolutionary studies.Organismic and Evolutionary Biolog

Influential Article Review - Feature Measurement Models and Natural Product Choice Effect

This paper examines innovation. We present insights from a highly influential paper. Here are the highlights from this paper: Face in China is a well-known word but still lacks a precise and authoritative definition. Other than the counterpart connotation of social norms in western culture, Chinese face is also a cultural construct strongly connected with situational context. To explore the general context and the specific connotation of Chinese face, this paper focuses on comparing the difference between reflective model and formative model when measuring the construct of Chinese face. We find that RM is more reliable and stable than FM in terms of face measurement but is inferior to FM in explaining the connotations of Chinese face. Moreover, we also explore the effects of different dimensions of Chinese face on consumer preference for ecological products. This study not only enriches the existing research on Chinese face, but also exploratively answers a controversial problem in this area. Furthermore, the findings in this study also provide theoretical support for building an environmentally-friendly society in China. For our overseas readers, we then present the insights from this paper in Spanish, French, Portuguese, and German

When perceptions are deadly: Policing, given the summer in Ferguson, Missouri and other similar stories, before and since

When law enforcement officers, regardless of race and ethnicity, are exposed to messages of Black violence, these perceptions of danger can become deadly. In 2014, the Michael Brown case in Ferguson, Missouri elevated this concern; but, there were many other cases previously publicized in the media such as Amadou Diallo, and Sean Bell. Using a content analysis of news reports from 1994 to summer 2015, this paper offers an assessment of media influence in the construction of public perceptions of Black dangerousness that seems to impact Black male and law enforcement interactions that become deadly for the former. The study also describes the local police-community contexts where such interactions seem likely. Patterns of contact and police narratives across a number of high profile police and Black male interactions are described. Noting these patterns, suggestions are offered toward creating a path for constructively addressing the problem of news-generated perceptions that can lead to needless tragedy for some. Community disempowerment and divergent community perspectives of law enforcement are often evident in these cases. This study is thus, an effort at enhancing awareness of modern-day news-perpetuated perceptions linking crime and Blackness

Adaptive strategies of African horse sickness virus to facilitate vector transmission

African horse sickness virus (AHSV) is an orbivirus that is usually transmitted between its equid hosts by adult Culicoides midges. In this article, we review the ways in which AHSV may have adapted to this mode of transmission. The AHSV particle can be modified by the pH or proteolytic enzymes of its immediate environment, altering its ability to infect different cell types. The degree of pathogenesis in the host and vector may also represent adaptations maximising the likelihood of successful vectorial transmission. However, speculation upon several adaptations for vectorial transmission is based upon research on related viruses such as bluetongue virus (BTV), and further direct studies of AHSV are required in order to improve our understanding of this important virus

How to create analogue black hole or white fountain horizons and LASER cavities in experimental free surface hydrodynamics?

Transcritical flows in free surface hydrodynamics emulate black hole horizons and their timereversed versions known as white fountains. Both analogue horizons have been shown to emit Hawking radiation, the amplification of waves via scattering at the horizon. Here we report on an experimental validation of the hydrodynamic laws that govern transcritical flows, for the first time in a free surface water channel using an analogue space-time geometry controlled by a bottom obstacle. A prospective study, both experimental and numerical, with a second obstacle downstream of a first one is presented to test in the near-future the analogous black hole laser instability, namely the super-amplification of Hawking radiation by successive bounces on a pair of black and white horizons within cavities which allow the presence of negative energy modes necessary for the amplification process. Candidate hydrodynamic regimes are discussed thanks to a phase diagram based on the scaled relative heights of both obstacles and the ratio of flow to wave speed in the upstream region.Comment: 19 pages, 19 figure

Innate Immunity and the Evolution of Resistance to an Emerging Infectious Disease in a Wild Bird

Innate immunity is expected to play a primary role in conferring resistance to novel infectious diseases, but few studies have attempted to examine its role in the evolution of resistance to emerging pathogens in wild vertebrate populations. Here, we used experimental infections and cDNA microarrays to examine whether changes in the innate and/or acquired immune responses likely accompanied the emergence of resistance in house finches (Carpodacus mexicanus) in the eastern United States subject to a recent outbreak of conjunctivitis-causing bacterium (Mycoplasma gallisepticum—MG). Three days following experimental infection with MG, we observed differences in the splenic transcriptional responses between house finches from eastern U.S. populations, with a 12-year history of MG exposure, versus western U.S. populations, with no history of exposure to MG. In particular, western birds down-regulated gene expression, while eastern finches showed no expression change relative to controls. Studies involving poultry have shown that MG can manipulate host immunity, and our observations suggest that pathogen manipulation occurred only in finches from the western populations, outside the range of MG. Fourteen days after infection, eastern finches, but not western finches, up-regulated genes associated with acquired immunity (cell-mediated immunity) relative to controls. These observations suggest population differences in the temporal course of the response to infection with MG and imply that innate immune processes were targets of selection in response to MG in the eastern U.S. population.Organismic and Evolutionary Biolog

Because I Was a Criminal and Drug Addict. : Experiences of Anti-Black Gendered Racism and Reproductive Injustice Among Black Pregnant and Postpartum Women with a Substance Use Disorder and Incarceration and Family Policing Histories

Racism pervades the US criminal legal and family policing systems, particularly impacting cases involving women with a history of a substance use disorder (SUD). Laws criminalizing SUD during pregnancy disproportionately harm Black women, as do family policing policies around family separation. Discrimination within intersecting systems may deter Black pregnant women with a SUD from seeking evidence-based pregnancy and substance use care. This convergent parallel mixed-methods study aimed to illuminate how systemic oppression influenced the lived experiences of Black mothers with a SUD, facing dual involvement in the criminal legal and family policing systems. Using convenience and snowball sampling techniques, we recruited 15 Black mothers who were incarcerated, used substances while pregnant, and had a history with family policing systems. We conducted semi-structured interviews and developed and distributed a scale questionnaire to describe participants’ experiences navigating overlapping systems of surveillance and control. Drawing on models of systemic anti-Black racism and sexism and reproductive justice, we assessed participants’ experiences of racism and gender-based violence within these oppressive systems. Participants described how intersecting systems of surveillance and control impeded their prenatal care, recovery, and abilities to parent their children in gender and racially specific ways. Although they mostly detailed experiences of interpersonal discriminatory treatment, particularly from custody staff while incarcerated and pregnant, participants highlighted instances of systemic anti-Black gendered racism and obstetric racism while accessing prenatal care and substance use treatment in carceral and community settings. Their narratives emphasize the need for action to measure and address the upstream macro-level systems perpetuating inequities

Automorphisms of graphs of cyclic splittings of free groups

We prove that any isometry of the graph of cyclic splittings of a finitely generated free group $F_N$ of rank $N\ge 3$ is induced by an outer automorphism of $F_N$. The same statement also applies to the graphs of maximally-cyclic splittings, and of very small splittings.Comment: 22 pages, 5 figures. Small modifications. To appear in Geometriae Dedicat

Establishing Telepathology in Africa: Lessons From Botswana

Few reports of telepathology in Africa exist in the medical literature. With the strong need for improvement in health care infrastructure and personnel training in many African nations, telepathology provides a rapid and versatile tool to improve clinical care and foster educational and research opportunities. We describe the challenges faced in establishing robotic telepathology (RT) services at a government referral center in Botswana and reflect on conditions under which such initiatives may be most likely to succeed in sub-Saharan Africa and other parts of the developing world