Tunneling transition to the Pomeron regime

We point out that, in some models of small-x hard processes, the transition to the Pomeron regime occurs through a sudden tunneling effect, rather than a slow diffusion process. We explain the basis for such a feature and we illustrate it for the BFKL equation with running coupling by gluon rapidity versus scale correlation plots.Comment: 17 pages, 5 figures, mpeg animations available from http://www.lpthe.jussieu.fr/~salam/tunneling/ . v2 includes additional reference

The BFKL Equation at Next-to-Leading Order and Beyond

On the basis of a renormalization group analysis of the kernel and of the solutions of the BFKL equation with subleading corrections, we propose and calculate a novel expansion of a properly defined effective eigenvalue function. We argue that in this formulation the collinear properties of the kernel are taken into account to all orders, and that the ensuing next-to-leading truncation provides a much more stable estimate of hard Pomeron and of resummed anomalous dimensions.Comment: LaTex, 12 pages, 1 eps figur

Minimal Subtraction vs. Physical Factorisation Schemes in Small-x QCD

We investigate the relationship of ``physical'' parton densities defined by kt-factorisation, to those in the minimal subtraction scheme, by comparing their small-x behaviour. We first summarize recent results on the above scheme change derived from the BFKL equation at NLx level, and we then propose a simple extension to the renormalisation-group improved (RGI) equation. In this way we are able the examine the difference between resummed gluon distributions in the Q_0 and MSbar schemes and also to show MSbar scheme resummed results for P_gg and approximate ones for P_qg. We find that, due to the stability of the RGI approach, small-x resummation effects are not much affected by the scheme-change in the gluon channel, while they are relatively more sensitive for the quark-gluon mixing.Comment: 14 pages, 8 figure

k-Factorization and Impact Factors at Next-to-leading Level

We further analyse,at next-to-leading log(s) level,the form of k-factorization and the definition of impact factors previously proposed by one of us,and we generalize them to the case of hard colourless probes. We then calculate the finite one-loop corrections to quark and gluon impact factors and we find them universal,and given by the same K factor which occurs in the soft timelike splitting functions

k-Factorization and Small-x Anomalous Dimensions

We investigate the consistency requirements of the next-to leading BFKL equation with the renormalization group, with particular emphasis on running coupling effects and NL anomalous dimensions. We show that, despite some model dependence of the bare hard Pomeron, such consistency holds at leading twist level, provided the effective variable $\alpha_s(t) log(1/x)$ is not too large. We give a unified view of resummation formulas for coefficient functions and anomalous dimensions in the Q_0-scheme and we discuss in detail the new one for the $q\bar{q}$ contributions to the gluon channel.Comment: Latex2e, 44 pages including 7 PostScript figure

Irreducible part of the next-to-leading BFKL kernel

On the basis of previous work by Fadin, Lipatov, and collaborators, and of our group, we extract the "irreducible" part of the next-to-leading (NL) BFKL kernel, we compute its (IR finite) eigenvalue function, and we discuss its implications for small-x structure functions. We find consistent running coupling effects and sizable NL corrections to the Pomeron intercept and to the gluon anomalous dimension. The qualitative effect of such corrections is to smooth out the small-x rise of structure functions at low values of Q2. A more quantitative analysis will be possible after the extraction of some additional, energy-scale dependent contributions to the kernel, which are not treated here.Comment: 16 pages, LaTex2e, including 3 eps figure

Heavy quark production as sensitive test for an improved description of high energy hadron collisions

QCD dynamics at small quark and gluon momentum fractions or large total energy, which plays a major role for HERA, the Tevatron, RHIC and LHC physics, is still poorly understood. For one of the simplest processes, namely bottom-antibottom production, next-to-leading-order perturbation theory fails. We show that the combination of two recently developed theoretical concepts, the k_perp-factorization and the next-to-leading-logarithmic-approximation BFKL vertex, gives perfect agreement with data. One can therefore hope that these concepts provide a valuable foundation for the description of other high energy processes.Comment: RevTeX, 4 pages, 7 figures titel and abstract changed, several formulations modified in the text, 1 figure droppe

Expanding running coupling effects in the hard Pomeron

We study QCD hard processes at scales of order k^2 > Lambda^2 in the limit in which the beta-function coefficient - b is taken to be small, but alphas(k) is kept fixed. The (nonperturbative) Pomeron is exponentially suppressed in this limit, making it possible to define purely perturbative high-energy Green's functions. The hard Pomeron exponent acquires diffusion and running coupling corrections which can be expanded in the b parameter and turn out to be dependent on the effective coupling b alphas^2 Y. We provide a general setup for this b-expansion and we calculate the first few terms both analytically and numerically.Comment: 36 pages, 15 figures, additional references adde

Purine-metabolising enzymes and apoptosis in cancer

The enzymes of both de novo and salvage pathways for purine nucleotide synthesis are regulated to meet the demand of nucleic acid precursors during proliferation. Among them, the salvage pathway enzymes seem to play the key role in replenishing the purine pool in dividing and tumour cells that require a greater amount of nucleotides. An imbalance in the purine pools is fundamental not only for preventing cell proliferation, but also, in many cases, to promote apoptosis. It is known that tumour cells harbour several mutations that might lead to defective apoptosis-inducing pathways, and this is probably at the basis of the initial expansion of the population of neoplastic cells. Therefore, knowledge of the molecular mechanisms that lead to apoptosis of tumoural cells is key to predicting the possible success of a drug treatment and planning more effective and focused therapies. In this review, we describe how the modulation of enzymes involved in purine metabolism in tumour cells may affect the apoptotic programme. The enzymes discussed are: ectosolic and cytosolic 5′-nucleotidases, purine nucleoside phosphorylase, adenosine deaminase, hypoxanthine-guanine phosphoribosyltransferase, and inosine-5′-monophosphate dehydrogenase, as well as recently described enzymes particularly expressed in tumour cells, such as deoxynucleoside triphosphate triphosphohydrolase and 7,8-dihydro-8-oxoguanine triphosphatase

The Gluon Impact Factors

We calculate in the next-to-leading approximation the non-forward gluon impact factors for arbitrary color state in the $t$-channel. In the case of the octet state we check the so-called "second bootstrap condition" for the gluon Reggeization in QCD, using the integral representation for the impact factors. The condition is fulfilled in the general case of an arbitrary space-time dimension and massive quark flavors for both helicity conserving and non-conserving parts.Comment: 32 pages, LaTeX, 1 EPS figure, uses epsf.sty and axodraw.st