A very rare complication of frontal sinusitis: Pott’s puffy tumor

Introduction. Pott’s puffy tumor is a very rare clinical condition characterized by subperiosteal abscess, a complication of frontal sinusitis, or as a result of head trauma. Aim. Early diagnosis of this condition is significantly important to prevent sequelae and severe neurological complications. This phenomenon, which is generally seen in children, can rarely be encountered in adults. Description of the case. In this report, we share a rare case of Pott’s puffy tumor in an adult patient. Conclusion. Pott’s puffy tumor, a rare complication of frontal sinusitis, should be considered to prevent neurological and intracranial complications

Efficacy of Interleukin-1 Targeting Treatments in Patients with Familial Mediterranean Fever

WOS: 000349015900004PubMed ID: 25139580Herein, we reported our experience in colchicine-resistant familial Mediterranean fever (FMF) patients who are treated with anti-interleukin-1 (IL-1) drugs. A retrospective review of medical records of anti-IL-1 recipients was performed. The main clinical characteristics of these patients and the evolution after anti-IL-1 were recorded. There were 20 patients (11 male [M] and 9 female [F]). Despite regular colchicine treatment, median number of attacks per month and per year was 1 (1-4) and 12 (4-50), respectively. Twelve patients were receiving anakinra, and eight patients were treated with canakinumab. The number of monthly and yearly attacks after IL-1 treatment was significantly decreased after the biologic agent (p < 0.05). One patient did not respond to the treatment, and one patient developed serious infection during anti-IL-1. We also observed a significant decrease in proteinuria in the amyloidosis complicated FMF patients. Anti-IL-1 targeting drugs seem safe and effective therapies in colchicine-resistant FMF

Efficacy of Interleukin-1 Targeting Drugs in Familial Mediterranean Fever Patients.

WOS: 00034438490233