3 research outputs found
Intestinal resection and primary anastomosis as treatment of intussusception due to ileum lipoma: case report and review
Intussusception is an unusual cause of intestinal occlusion in adults, accounting for 5% of cases, and is the result of an underlying pathology in 90% of cases, 60% of which are tumors. The pathogenesis describes the invagination of an intestinal segment into the lumen of an adjacent segment with subsequent alterations in irrigation, risk of necrosis and perforation. Surgical management is indicated in adult patients to restore intestinal transit and to exclude malignancy as the axis of the intussusception. We present the case of a 58-year-old female patient with enteric intussusception at ileum due to lipoma, who underwent bowel resection and manual end-to-end intestinal anastomosis in two planes
Actividad antihipertensiva de péptidos de zeína extraídos de maíz (Zea mays L.) criollo (azul y rojo) del Estado de México
Objective: To evaluate the antihypertensive activity of peptides extracted from nixtamalized and non-nixtamalized creole corn (blue and red) zein from the Estado de México.
Design / methodology / approach: Bioinformatic tools, such as the NCBI database, were used to search for primary sequences of the maize zein protein. The methodology included a prediction of peptides with antihypertensive activity through various bioinformatic servers. Inhibitory activity was determined by percentage regression. Statistical analysis was performed to assess possible significant differences using the Tukey test (p <0.05).
Results: The following peptides were found by in silico hydrolysis: IFSILMLLA, LSACVLDATI, TASVCENPTL, LPLSPLLFQQ, SPALSLVQSL, LSPYSQQQQF, PFSQLATAY, LPFYQQFSAN and PAAFYQQHII that showed inhibition activity. The results showed that the GH (grade of hydrolysis) was higher in blue corn (13.96 ± 0.02) than in red corn (10.38 ± 0.79) without nixtamalization, while, with the nixtamalization process, this parameter was also higher in blue corn (10.52 ± 0.57) than in red corn (8.96 ± 0.01).
Study limitations / implications: The enzyme used for hydrolysis generates oligopeptides that may not be as closely related to the angiotensin-converting enzyme.
Findings / Conclusions: In vitro antihypertensive activity of unhydrolyzed blue corn zein showed a lower percentage of ACE inhibition compared to unhydrolyzed red corn. Trypsin hydrolysis only increases ACE inhibitory activity in blue corn at a concentration of 0.3 mg / mL without nixtamalizing.Objetivo: Evaluar la actividad antihipertensiva de péptidos extraídos de zeína de maíz criollo azul y rojo nixtamalizado y sin nixtamalizar del Estado de México.
Diseño/metodología/aproximación: Se emplearon herramientas bioinformáticas, tales como la base de datos NCBI para la búsqueda de secuencias primarias de la proteína zeína del maíz. La metodología incluyó una predicción de los péptidos con actividad antihipertensiva a través de diversos servidores bioinformáticos. La actividad inhibitoria se determinó mediante la regresión del porcentaje. Se realizó un análisis estadístico para evaluar las posibles diferencias significativas utilizando la prueba de Tukey (p<0.05).
Resultados: Por medio de la hidrólisis in sílico se encontraron los siguientes péptidos: IFSILMLLA, LSACVLDATI, TASVCENPTL, LPLSPLLFQQ, SPALSLVQSL, LSPYSQQQQF, PFSQLATAY, LPFYQQFSAN y PAAFYQQHII que mostraron actividad de inhibición de la ECA. Los resultados mostraron que el GH de la zeína fue mayor en maíz azul (13.96±0.02) que en maíz rojo (10.38±0.79) sin nixtamalizar, mientras que, con el proceso de nixtamalización, este parámetro también fue mayor en el maíz azul (10.52±0.57) que en el maíz rojo (8.96±0.01).
Limitaciones del estudio/implicaciones: La enzima utilizada para la hidrólisis enzimática genera oligopéptidos que tal vez no puedan ser tan afines a la enzima convertidora de angiotensina.
Hallazgos/conclusiones: La actividad antihipertensiva in vitro del maíz azul sin hidrolizar mostraron un menor porcentaje de inhibición de la ECA con respecto al maíz rojo sin hidrolizar. La hidrólisis con tripsina solo incrementa la actividad inhibitoria de la ECA en maíz azul a concentración de 0.3 mg/mL sin nixtamalizar
Determination of optimal areas for the establishment of buffalo herds and German grass in Tabasco, Mexico
Objective: To determine optimal (suitable) areas for the establishment of fattening buffalo herds (Bubalus bubalis) and german grass (Echinochloa polystachya Kunth Hitchc) based on biophysical environmental conditions that favor the comfort state of the animal species and the better development of the plant species.
Design/methodology/approach: The methodology consisted of an analysis of the bioclimatic parameters for water buffalo and agroclimatic parameters for german grass in the state from Tabasco. A comparative table of the optimal biophysical variables of the water buffalo and the german grass was elaborated with respect to the digital geographic base of soils and the climatological normals registered in the state from Tabasco. Edaphoclimatic maps were elaborated for the establishment of buffalo herds associated with german grass from a cartographic crossing.
Results: Obtaining the edaphoclimatic aptitude map of both species at a scale of 1:135,000.
Limitations of the study/implications: In the state of Tabasco, there is a lack of basic information on the soil and climatic conditions suitable for water buffalo, since its exploitation is recent.
Findings/conclusions: The areas for the establishment of buffalo herds and German grass were identified. 4.29% of the state of Tabasco has suitable potential, followed by 56.67% classified as moderately suitable, while 38.48% were classified as unsuitableObjective: To determine optimal (suitable) areas for the establishment of buffalo (Bubalus bubalis) herds fattened with German grass (Echinochloa polystachya Kunth Hitchc), based on the biophysical environmental conditions that favor the comfort of the animal species and the best development of the plant species.Design/Methodology/Approach: An analysis of the bioclimatic parameters for water buffalo and the agroclimatic parameters for German grass was carried out in the state of Tabasco, Mexico. A comparative table of the optimal biophysical variables of water buffalo and German grass was developed from the digital soil geographic databases and the climatological normals recorded in the state of Tabasco. Edaphoclimatic maps were developed to establish buffalo herds associated with German grass, based on a cartographic cross-checking.Results: The soil-climatic aptitude map of both species was developed at a scale of 1:135,000.Study Limitations/Implications: Given its recent introduction, there is a lack of basic information on the edaphoclimatic conditions suitable for water buffalo in the state of Tabasco.Findings/Conclusions: The areas for the establishment of buffalo herds and German grass were identified. Regarding their potentiality, 4.29% of the state of Tabasco is suitable, 56.67% was classified as moderately suitable, and 38.48% is not suitable