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    Detection of H<sub>2</sub>O<sub>2</sub> at the Nanomolar Level by Electrode Modified with Ultrathin AuCu Nanowires

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    Bimetallic AuCu nanowires (AuCuNWs) are synthesized via a facile water solution method at room temperature. Enhanced electrocatalytic activity is observed toward the oxidation of H<sub>2</sub>O<sub>2</sub>, which makes the AuCu nanowire, along with its unique catalytic properties, intriguing bifunctional mechanism, and surface atomic construction, a promising platform for the amplification of interfacing signal. A highly sensitive H<sub>2</sub>O<sub>2</sub> biosensor is thus developed on the base of the as-prepared AuCuNW catalyst. A very low real determination limit (2.0 nM) was reached, and a linear range as wide as 5 orders of magnitude was demonstrated. In addition, a trace amount of H<sub>2</sub>O<sub>2</sub>, which was released from Raw 264.7 cells, was selectively detected, hinting at the possible applications for real-time quantitative detection of H<sub>2</sub>O<sub>2</sub> in a biological environment
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