Seasonal Spatiotemporal Changes in the NDVI and its Driving Forces in Wuliangsu Lake Basin, Northern China from 1990 to 2020

  In the context of global climate change, many studies have focused on the inter–annual vegetation variation trends and their response to precipitation and temperature, but ignored the effects of seasonal variability. This study explored the relationship between normalized difference vegetation index (NDVI) and seasonal climate elements in the Wuliangsu Lake Basin area from 1990 to 2020 and quantified the impacts of human activities on vegetation dynamics. We used Landsat series data to analyse the spatial and temporal variation of the NDVI using the trend analysis method, the Theil–Sen median, the Mann–Kendall test, and the Hurst index. Then, we used meteorological data and land use data to quantify the effects of human activities using residual analysis, and correlation methods to determine the driving forces of NDVI variations. The results showed that the NDVI changes presented obvious regional characteristics, with a decreasing trend from southeast to northwest in Wuliangsu Lake Basin. Due to global warming, the start of the growing season (SOS) is 4.3 days (2001 to 2010) and 6.8 days (2011 to 2020) earlier compared with 1990 to 2000. The end of the season (EOS) is advanced by 3.6 days (2001 to 2010) and delayed by 8.9 days (2011 to 2020). Seasonal (spring, summer, autumn, and winter) NDVIs with precipitation and temperature show spatial heterogeneity. Further, changes in grasslands and woodlands were vulnerable to climate change and human activities. Since the beginning of the 21st century, human activity was the driving force for vegetation improvement in the Dengkou, west-central, north and southwest regions, where ecological instability is weak. This finding can provide a theoretical basis for the implementation of the same type of ecological restoration projects and the construction of ecological civilization, and contribute to the regional green and sustainable development.   Keywords: Climate change, Driving forces, Human activities, Seasonal spatiotemporal changes, Wuliangsu Lake Basi

Bacteriological and Molecular Identification of Bartonella Species in Cats from Different Regions of China

With the improvements in diagnostic techniques, Bartonella henselae (B. henselae) infection has recently been recognized to cause a widening spectrum of diseases. Cats are the natural reservoir hosts of B. henselae. The current study aims to investigate the prevalence of B. henselae infection in the cat populations in China. Polymerase chain reaction (PCR) and bacterial cultures confirm that 12.7% of the tested cats were positive for the infection. Old age and outdoor exposure were statistically associated with the infection. Multilocus sequence typing and eBURST analysis of the cat isolates collected in the present study show that 65.4% of the isolates belong to sequence type 1 (ST1). Three new STs (ST16–18) were identified in Midwestern China. These results may aid our understanding of the population structure of B. henselae in China and the relationship between human and cat strains in subsequent studies

Study on sandstorm in the western section of Hexi Corridor of 2020

A diagnostic analysis of the dust storm weather occurring in the western part of the Hexi Corridor from 27-30 June 2020 was carried out using Jiuquan city’s live data, as well as ECMWF numerical forecasts, and the NCEP reanalysis information was used to draw a theta dust storm model based on the routing principle. The results show that: 1.In the early stage of sandstorm, there was no precipitation in Suzhou and Jinta counties in March and April, which resulted in dry surface and thickened soil layer. These factors created favorable conditions for the occurrence of dust weather. 2.Development of unstable trough eastward in front of the ridge of Mountain Ural at 500 hPa, The cold high pressure is continuously strengthened in the process of moving, which is the large-scale system leading to the sandstorm. Thermal depression in front of ground cold front is the main cause for the outbreak of the severe sandstorm. 3.The beginning and ending time of the sandstorm can be accurately predicted by the simulation chart of sandstorm forecast, which has a good indication significance for the sandstorm forecast in the Hexi area

MiR-103-3p promotes hepatic steatosis to aggravate nonalcoholic fatty liver disease by targeting of ACOX1

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a major risk factor for hepatocellular carcinoma, and alterations in miRNA expression are related to the development of NAFLD. However, the role of miRNAs in regulating the development of NAFLD is still poorly understood. METHODS: We used qRT-PCR to detect the level of miR-103-3p in both cell and mouse models of NAFLD. Biochemical assays, DCF-DA assays, Oil red O staining and HE staining were used to detect the role of miR-103-3p in NAFLD development. Target genes of miR-103-3p were predicted using the TargetScan database and verified by qRT-PCR, western blot and dual-luciferase assays. RESULTS: The expression of miR-103-3p increased in both NAFLD model cells and liver tissues from the NAFLD mouse model. Inhibition of miR-103-3p significantly alleviated the accumulation of lipid droplets in free fatty acid-treated L02 cells and liver tissues from mice with NAFLD. Inhibition of miR-103-3p reduced the contents of H CONCLUSIONS: These findings identified a negative regulatory mechanism between ACOX1 and miR-103-3p that promotes the pathogenesis of NAFLD and suggested that inhibition of miR-103-3p may be a potential treatment strategy for NAFLD

Correlation of 3'-phosphoadenosine-5'-phosphosulfate synthase 1 (PAPSS1) expression with clinical parameters and prognosis in esophageal squamous cell carcinoma

Background. In recent years, 3'- phosphoadenosine-5'-phosphosulfate synthase 1 (PAPSS1) has been found to be highly expressed in some cancers and significantly associated with prognosis. Nevertheless, the role of PAPSS1 in esophageal squamous cell carcinoma (ESCC) is poorly understood. Methods. In this study, PAPSS1 expression in ESCC samples was researched through real-time quantitative polymerase chain reaction (qPCR), immunohistochemistry (IHC), and western blot (WB) techniques. siRNA technology was then used to inhibit PAPSS1 expression in ESCC cells, and cytologic tests were conducted to research gene affection on cell apoptosis, proliferation, and migration. Then, the expression of Bcl2, Ki67, and Snail was detected using qPCR and WB tests. These experimental data were analyzed by GraphPad software, where the P-value <0.05 was statistically significant. Results. The results showed that PAPSS1 expression level in ESCC tissues was higher than in the adjacent tissues. The data also showed that PAPSS1 was significantly correlated with N stage, and that the patients with high expressions had longer survival time. After transfection for 48 hours, the cell apoptosis rate of siRNA-PAPSS1 transfected groups decreased significantly, whereas the cell proliferation rate and migration ability increased relative to the control. At the same time, the expression levels of Bcl2, Ki67 and Snail were all upregulated by siRNA-PAPSS1. PAPSS1, however, was suppressed. Conclusions. PAPSS1 may be an ESCC suppressor gene, and its specific molecular mechanism in ESCC needs to be further studied

Investigation and analysis of the mental pressure of outpatient medical attendants and nurses during the COVID-19 pandemic in china

261-271Certain sicknesses or contaminations influence an enormous number of individuals in a limited capacity to focus time. A neighbourhood endemic illness can flare-up into a scourge influencing the entire populace or district which on occasion reach out to different nations and mainlands and become pandemic. Pandemics brings about death toll just like the economy. Pooled endeavors and assets, compelling sharing of information, equal numerous methodologies just as the physical and mental condition of forefront staff impact the board of pandemics. The COVID illness COVID-19 brought about by SARS-CoV-2 began in Dec 2019 from Wuhan in China, is currently an overall general wellbeing crisis influencing a huge number of people. It influences numerous cutting edge medical care laborers as well. Here, we contemplated mental pressure and proficient personality of Nurses and Staff for potential relationships, assuming any, and break down affecting elements. We utilized a purposive testing method with 415 Nurses and Staff in Nanjing, China through an overall data poll, seen pressure scale, and nursing proficient personality survey. Attendants and Staff' inception, month to month everyday costs, and their insight on plague counteraction and treatment have indicated a critical effect on their mental pressure (PPP< 0.01, r = -00.457). Expanded mental pressure, had a lower feeling of expert personality. Generally speaking, the examination of information on saw pressure and expert character pandemic proposes that feelings of anxiety are contrarily relative to information in compelling methods of taking care of the pandemic. Attendants and Staff with clinical practice fared better as far as expert character. The examination proposes Nurses and Staff to remain zeroed in on investigations, clinical practice, and directing, whenever required

Investigation and analysis of the mental pressure of outpatient medical attendants and nurses during the COVID-19 pandemic in china

Certain sicknesses or contaminations influence an enormous number of individuals in a limited capacity to focus time. A neighbourhood endemic illness can flare-up into a scourge influencing the entire populace or district which on occasion reach out to different nations and mainlands and become pandemic. Pandemics brings about death toll just like the economy. Pooled endeavors and assets, compelling sharing of information, equal numerous methodologies just as the physical and mental condition of forefront staff impact the board of pandemics. The COVID illness COVID-19 brought about by SARS-CoV-2 began in Dec 2019 from Wuhan in China, is currently an overall general wellbeing crisis influencing a huge number of people. It influences numerous cutting edge medical care laborers as well. Here, we contemplated mental pressure and proficient personality of Nurses and Staff for potential relationships, assuming any, and break down affecting elements. We utilized a purposive testing method with 415 Nurses and Staff in Nanjing, China through an overall data poll, seen pressure scale, and nursing proficient personality survey. Attendants and Staff' inception, month to month everyday costs, and their insight on plague counteraction and treatment have indicated a critical effect on their mental pressure (P&lt; 0.010). Essentially, Nurse's and Staff's sexual orientation, inception, clinical practices, and information on counteraction and treatment, and whether they effectively learn such information sway altogether on their expert personality (P&lt; 0.010). The general score of mental pressure were (24.470±07.350) and proficient personality had 72.470±08.070. The pressure condition showed a negative connection with the level of expert character (P&lt; 0.01, r = 00.457). Expanded mental pressure, had a lower feeling of expert personality. Generally speaking, the examination of information on saw pressure and expert character pandemic proposes that feelings of anxiety are contrarily relative to information in compelling methods of taking care of the pandemic. Attendants and Staff with clinical practice fared better as far as expert character. The examination proposes Nurses and Staff to remain zeroed in on investigations, clinical practice, and directing, whenever required