Enabling Access Control for Encrypted Multi-Dimensional Data in Cloud Computing through Range Search

With the growing popularity of cloud computing, data owners are increasingly opting to outsource their data to cloud servers due to the numerous benefits it offers. However, this outsourcing raises concerns about data privacy since the data stored on remote cloud servers is not directly controlled by the owners. Encryption of the data is an effective approach to mitigate these privacy concerns. However, encrypted data lacks distinguishability, leading to limitations in supporting common operations such as range search and access control. In this research paper, we propose a method called RSAC (Range Search Supporting Access Control) for encrypted multi-dimensional data in cloud computing. Our method leverages policy design, bucket embedding, algorithm design, and Ciphertext Policy-Attribute Based Encryption (CPABE) to achieve its objectives. We present extensive experimental results that demonstrate the efficiency of our method and conduct a thorough security analysis to ensure its robustness. Our proposed RSAC method addresses the challenges of range search and access control over encrypted multi-dimensional data, thus contributing to enhancing privacy and security in cloud computing environments

Common genetic variants in ADCY5 and gestational glycemic traits.

Two meta-analysis of genome wide association studies identified two variants at adenylate cyclase 5 (ADCY5) associated with type 2 diabetes mellitus, fasting and 2-hour glucose in non-pregnant individuals of European descent. The objective of our study was to explore the role of common variants in ADCY5 on gestational glycemic traits, including plasma glucose, insulin values, β cell function and insulin resistance in the fasted state as well as plasma glucose 1 hour after a 50-gram glucose challenge test among Chinese Han women. Homoeostasis model assessment (HOMA) was used to quantify β cell function (HOMA1-β and HOMA2-β) and insulin resistance (HOMA1-IR and HOMA2-IR). Thirty-five single nucleotide polymorphisms (SNPs) in ADCY5 were genotyped in 929 unrelated Chinese Han women with singleton pregnancies. Three SNPs (rs6797915, rs9856662 and rs9875803) displayed evidence for association with plasma glucose 1 hour after a 50-gram glucose challenge test (P = 0.042, 0.018 and 0.018, respectively), one (rs6777397) displayed evidence for association with HOMA1-β (P = 0.014), and one (rs6762009) displayed evidence for association with HOMA1-IR (P = 0.033). These results provide additional insight into the effects of genetic variation within ADCY5 in glucose metabolism, especially during pregnancy and in non-European descent populations

Meta-Analysis Results on the Association Between TP53 Codon 72 Polymorphism With the Susceptibility to Oral Cancer

Objectives: TP53 is an important tumor suppressor gene to maintain genomic integrity, and its mutations increase the susceptibility to oral carcinoma. Previous published studies have reported the relation of TP53 codon 72 polymorphism with the risk of oral carcinoma, but the results remain controversial and inconclusive.Methods: We therefore utilized meta-analysis based on a comprehensive search in PubMed, EMBASE, and Google of Scholar databases up to August 19, 2017.Results: Total 3,525 cases and 3,712 controls from 21 case-control studies were selected. We found no significant association between TP53 codon 72 polymorphism and oral carcinoma susceptibility in all genetic contrast models, including subgroup analysis based on control source and ethnicity. Furthermore, TP53 codon 72 polymorphism was not significant associated with oral carcinoma susceptibility in tobacco or alcohol use, and HPV infection status. Our results were confirmed by sensitivity analysis and no publication bias was found.Conclusions: Taken together, our data indicate that TP53 codon 72 polymorphism is not associated with the susceptibility to oral carcinoma

Deficits of congenital amusia beyond pitch: Evidence from impaired categorical perception of vowels in Cantonese-speaking congenital amusics.

Congenital amusia is a lifelong disorder of fine-grained pitch processing in music and speech. However, it remains unclear whether amusia is a pitch-specific deficit, or whether it affects frequency/spectral processing more broadly, such as the perception of formant frequency in vowels, apart from pitch. In this study, in order to illuminate the scope of the deficits, we compared the performance of 15 Cantonese-speaking amusics and 15 matched controls on the categorical perception of sound continua in four stimulus contexts: lexical tone, pure tone, vowel, and voice onset time (VOT). Whereas lexical tone, pure tone and vowel continua rely on frequency/spectral processing, the VOT continuum depends on duration/temporal processing. We found that the amusic participants performed similarly to controls in all stimulus contexts in the identification, in terms of the across-category boundary location and boundary width. However, the amusic participants performed systematically worse than controls in discriminating stimuli in those three contexts that depended on frequency/spectral processing (lexical tone, pure tone and vowel), whereas they performed normally when discriminating duration differences (VOT). These findings suggest that the deficit of amusia is probably not pitch specific, but affects frequency/spectral processing more broadly. Furthermore, there appeared to be differences in the impairment of frequency/spectral discrimination in speech and nonspeech contexts. The amusic participants exhibited less benefit in between-category discriminations than controls in speech contexts (lexical tone and vowel), suggesting reduced categorical perception; on the other hand, they performed inferiorly compared to controls across the board regardless of between- and within-category discriminations in nonspeech contexts (pure tone), suggesting impaired general auditory processing. These differences imply that the frequency/spectral-processing deficit might be manifested differentially in speech and nonspeech contexts in amusics-it is manifested as a deficit of higher-level phonological processing in speech sounds, and as a deficit of lower-level auditory processing in nonspeech sounds

The d' of the between- and within-category pairs for the amusic and control participants in the four stimulus continua in the discrimination task.

<p>The d' of the between- and within-category pairs for the amusic and control participants in the four stimulus continua in the discrimination task.</p

Schematic diagram of the stimulus continua.

<p>(A) Lexical tone and pure tone continuum (/55/ to /25/) with a step size of ΔF0 ≈ 0.90 semitone at the starting frequency which decreased towards the end. (B) Vowel continuum (/u/ to /o/) with a step size of ΔF1 ≈ 42Hz. (C) VOT continuum (/p/ to /p^h/) with a step size of 8 ms.</p

Boundary position and width for the amusic and control participants in the four stimulus continua in the identification task.

<p>Boundary position and width for the amusic and control participants in the four stimulus continua in the identification task.</p

Response curves for the amusic and control participants in the four stimulus continua in the identification task.

<p>Top left panel: Rate of /ji55/ (醫 ‘doctor’) responses in the lexical tone continuum; top right panel: Rate of high level pitch responses in the pure tone continuum; bottom left panel: Rate of /fu55/ (膚 ‘skin’) responses in the vowel continuum; bottom right panel: Rate of /pa55/ (疤 ‘scar’) responses in the VOT continuum.</p

The d' of stimulus pairs for the amusic and control participants in the four stimulus continua in the discrimination task.

<p>The d' of stimulus pairs for the amusic and control participants in the four stimulus continua in the discrimination task.</p

Demographic characteristics of the amusic and control participants.

<p>The results (<i>p</i>-value) of independent-samples <i>t</i>-tests comparing the amusic and control participants in age and the scores of the Online Identification Test of Congenital Amusia test are also reported. n.s. = not significant.</p