Application of Laparoscopy in Comprehensive Staging Operation of Ovarian Cancer Based on Electronic Medical Blockchain Technology

Ovarian cancer has always entangled most women. Studies have shown that the prevalence of ovarian cancer ranks third in female reproductive malignancies, and the mortality rate has always been the highest. The reason is mainly because the diagnosis and treatment of preovarian cancer has always been a big problem. However, the emergence of laparoscopy can well solve this problem, especially laparoscopy assisted by blockchain technology, which plays a huge role in the overall staging of ovarian cancer. This article proposes the application research of laparoscopy in the comprehensive staging of ovarian cancer based on electronic medical blockchain technology. First of all, this article uses the literature method to study the clinical characteristics and surgical classification of ovarian cancer, as well as the application status of blockchain technology and laparoscopic technology. Secondly, it designed an application experiment based on electronic medical blockchain technology to assist laparoscopy in the comprehensive staging of ovarian cancer and analyzed the comparison of the laparoscopic group and the control group in the comprehensive staging of ovarian cancer. The results of the study showed that the amount of bleeding in the laparoscopic group was 103.5 ml, while the amount of bleeding in the control group was 141.1 ml; the proportion of tertiary pain in the laparoscopic group was 11.37%, and the proportion of tertiary pain in the control group was 31.82%. From this, it can be seen that, in the comprehensive staging operation for ovarian cancer, the laparoscopic group has less intraoperative blood loss than the control group and lower pain, and the treatment effect is better

The Microstructure and Mechanical Properties of Dual-Spot Laser Welded-Brazed Ti/Al Butt Joints with Different Groove Shapes

Laser welding-brazing was performed to join Ti and Al together. The dual-spot laser beam mode was selected as the heat source in this study. Ti-6Al-4V and 6061-T6 Al alloys were selected as the experimental materials. Al-12Si welding wire was selected as the filler material. The effect of groove shape on the weld appearance, microstructure, temperature field, and mechanical performance of Ti/Al welded-brazed butt joints was investigated. The interfacial intermetallic compound (IMC) layer at the Ti/Weld brazing interface was inhomogeneous in joints with I-shaped and Y-shaped grooves. In Ti/Al joints with V-shaped grooves, the homogeneity of temperature field and IMC layer was improved, and the maximum thickness difference of IMC layer was only 0.20 μm. Nano-sized granular Ti7Al5Si12, Ti5Si3, and Ti(Al,Si)3 constituted the IMCs. The tensile strength of Ti/Al joints with V-shaped grooves was the highest at 187 MPa. The fracture mode transformed from brittle fractures located in the IMC layer to ductile fractures located in the Al base metal, which could be attributed to the improvement of the IMC layer at the brazing interface

Understanding the effect of moderate concentration SDS on CO2 hydrates growth in the presence of THF

Additives like Tetrahydrofuran (THF) and Sodium Dodecyl Sulfate (SDS) improve CO2 hydrates thermal stability and growth rate when used separately. It has been hypothesised that combining them could improve the kinetics of growth and the thermodynamic stability of CO2 hydrates. We exploit atomistic molecular dynamics simulation to investigate the combined impact of THF and SDS under different temperatures and concentrations. The simulation insights are verified experimentally using pendant drop tensiometry conducted at ambient pressures and high-pressure differential scanning calorimetry. Our simulations revealed that the combination of both additives is synergistic at low temperatures but antagonistic at temperatures above 274.1 K due to the aggregation SDS molecules induced by THF molecules. These aggregates effectively remove THF and CO2 from the hydrate-liquid interface, thereby reducing the driving force for hydrates growth. Experiments revealed that the critical micelle concentration of SDS in water decreases by 20% upon the addition of THF. Further experiments showed that only small amounts of SDS with THF is sufficient to increase the CO2 storage efficiency by over 40% compared to results obtained without promoters. These results provide microscopic insights into the mechanisms of THF and SDS promoters on CO2 hydrates, which allow for determining the optimal condition for hydrate growth

EpiReSIM: A Resampling Method of Epistatic Model without Marginal Effects Using Under-Determined System of Equations

Simulation experiments are essential to evaluate epistasis detection methods, which is the main way to prove their effectiveness and move toward practical applications. However, due to the lack of effective simulators, especially for simulating models without marginal effects (eNME models), epistasis detection methods can hardly verify their effectiveness through simulation experiments. In this study, we propose a resampling simulation method (EpiReSIM) for generating the eNME model. First, EpiReSIM provides two strategies for solving eNME models. One is to calculate eNME models using prevalence constraints, and another is by joint constraints of prevalence and heritability. We transform the computation of the model into the problem of solving the under-determined system of equations. Introducing the complete orthogonal decomposition method and Newton’s method, EpiReSIM calculates the solution of the underdetermined system of equations to obtain the eNME model, especially the solution of the high-order model, which is the highlight of EpiReSIM. Second, based on the computed eNME model, EpiReSIM generates simulation data by a resampling method. Experimental results show that EpiReSIM has advantages in preserving the biological properties of minor allele frequencies and calculating high-order models, and it is a convenient and effective alternative method for current simulation software

Experimental study on cable coupling effects of lightning strikes on a metal mast

[Objective] This paper carries out an experimental study on the coupling response characteristics of the internal cables of a metal mast when struck by lightning. [Method] A lightning induction coupling test platform is built for the cable system inside the mast. The induced voltages of the coaxial cables, two-core single shielded cables and multi-core double shielded cables are measured under four kinds of termination load characteristics (open circuit at both ends of core wire; end of core wire near to the ground connected to the load; end of core wire far from the ground connected to the load; and both ends of core wire connected to the load). From the perspective of time domain and frequency domain, an analysis is made of the influence of load characteristics on the induced voltage and shielding effects. [Results] The induced voltage of the cable reaches its maximum value when the far ground terminal is grounded by the load. When the near ground terminal is grounded by the load, the main frequency band of the induced voltage frequency response exceeds the lightning current, whereas they are similar under other load characteristics. Grounding the inner shielding layer can reduce the peak value of the induced voltage, but does not affect the main frequency band of the frequency response. The voltage peak value is most significantly reduced when both ends of the core wire are open-circuited or when the end of the core wire far from the ground is connected to the load (approximately 59.3% and 77.2% of the value when the inner shielding layer is ungrounded). In addition, the induced voltage peaks of the three types of cables exhibit considerable differences. However, the rise time and half-peak time of the induced voltage for each cable show insignificant differences. [Conclusion] This study reveals the influence of terminal load characteristics on cable coupling induced voltage when lightning strikes the metal mast of a ship, as well as providing basic data support for the subsequent calculation of the coupling effect

Calculation of lightning attachment points on ships based on lightning leader progression model and experimental verification

ObjectiveIn order to improve lightning protection measures for ships, it is vital to evaluate the lightning strike risk and lightning rod protection effect. MethodsThis paper proposes a leader development model that can simulate the natural leader progression, and introduces a ship model to analyze its lightning attachment process. Analyses are made of the electric field distribution on the surface of the ship when the downward leader is approaching at different areas, of the probability of the ship being struck by lightning at each location, and of the protection effect of the lightning rod on the ship. Finally, the calculation results are verified by a ship scaled-down model discharge test carried out in the laboratory.ResultsThe lightning strike attachment point is mainly concentrated in the relatively protruding position of the structure on the ship, and the lightning rod has a positive effect on the potential distribution on the surface of the ship. However, the final lightning strike point is determined by the development area of the downward leader.ConclusionsCombining simulation analysis with the test results, the weak points of direct lightning protection on the surface of the ship are obtained. It is found that the location of the final lightning strike attachment point of the ship is closely related to the connection process of the by-directional leaders, and that the proposed leader progression model can provide accurate predictions of lightning strike points