2 research outputs found
Pulsed plasma physical vapour deposition approach towards the facile synthesis of multilayer and monolayer graphene for anticoagulation applications
We demonstrate the growth of multilayer and single layer graphene on copper foil using
bipolar pulsed direct current (DC) magnetron sputtering of a graphite target in pure Ar
atmosphere. Single layer and few layer graphene films (SG and FLG) are deposited at
temperatures ranging from 700-920 °C in less than 30 minutes. We find that the deposition and
post-deposition annealing temperatures influence the layer thickness and quality of the graphene
films formed. The films were characterized using atomic force microscopy (AFM), scanning
electron microscopy (SEM), High resolution transmission electron microscopy (HRTEM),
Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and optical transmission
spectroscopy techniques. Based on the above studies, a diffusion controlled mechanism was
proposed for the graphene growth. A single step whole blood assay was used to investigate the
anticoagulant activity of graphene surfaces. Platelet adhesion, activation and morphological
changes on the graphene/glass surfaces compared to bare glass were analysed using fluorescence
microscopy and SEM techniques. We have found significant suppression of the platelet
adhesion, activation and aggregation on the graphene covered surfaces compared to the bare
glass, indicating the anticoagulant activity of the deposited graphene films. Our production
technique represents an industrially relevant method for the growth of single and few layer
graphene for various applications including the biomedical field
Pulsed-Plasma Physical Vapor Deposition Approach Toward the Facile Synthesis of Multilayer and Monolayer Graphene for Anticoagulation Applications
We
demonstrate the growth of multilayer and single-layer graphene
on copper foil using bipolar pulsed direct current (DC) magnetron
sputtering of a graphite target in pure argon atmosphere. Single-layer
graphene (SG) and few-layer graphene (FLG) films are deposited at
temperatures ranging from 700 °C to 920 °C within <30
min. We find that the deposition and post-deposition annealing temperatures
influence the layer thickness and quality of the graphene films formed.
The films were characterized using atomic force microscopy (AFM),
scanning electron microscopy (SEM), high-resolution transmission electron
microscopy (HRTEM), Raman spectroscopy, X-ray photoelectron spectroscopy
(XPS), and optical transmission spectroscopy techniques. Based on
the above studies, a diffusion-controlled mechanism was proposed for
the graphene growth. A single-step whole blood assay was used to investigate
the anticoagulant activity of graphene surfaces. Platelet adhesion,
activation, and morphological changes on the graphene/glass surfaces,
compared to bare glass, were analyzed using fluorescence microscopy
and SEM techniques. We have found significant suppression of the platelet
adhesion, activation, and aggregation on the graphene-covered surfaces,
compared to the bare glass, indicating the anticoagulant activity
of the deposited graphene films. Our production technique represents
an industrially relevant method for the growth of SG and FLG for various
applications including the biomedical field