69 research outputs found

    Ruimte voor werk. bouwrijpe bedrijventerreinen, economische ontwikkeling en ruimtelijke planning in Vlaanderen

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    Is there a shortage of new industrial sites in Flanders? This paper develops a method to evaluate the availability of industrial sites. The evaluation is based on the idea that a "strategic supply" should always be available in each sub-region in order to guarantee further economic development. The results indicate that the available area for industrial sites is clearly insufficient in large parts of Flanders. We also formulate several policy recommendations. The Flemish Govermnent has to take simultaneously structural and ad hoc measures. The structural measures should prevent that policy induced shortage of supply can pop up in the future. The ad hoc measures should speed up the supply in the next years.

    Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

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    A safe and effective vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be required to end the coronavirus disease 2019 (COVID-19) pandemic1–8. For global deployment and pandemic control, a vaccine that requires only a single immunization would be optimal. Here we show the immunogenicity and protective efficacy of a single dose of adenovirus serotype 26 (Ad26) vector-based vaccines expressing the SARS-CoV-2 spike (S) protein in non-human primates. Fifty-two rhesus macaques (Macaca mulatta) were immunized with Ad26 vectors that encoded S variants or sham control, and then challenged with SARS-CoV-2 by the intranasal and intratracheal routes9,10. The optimal Ad26 vaccine induced robust neutralizing antibody responses and provided complete or near-complete protection in bronchoalveolar lavage and nasal swabs after SARS-CoV-2 challenge. Titres of vaccine-elicited neutralizing antibodies correlated with protective efficacy, suggesting an immune correlate of protection. These data demonstrate robust single-shot vaccine protection against SARS-CoV-2 in non-human primates. The optimal Ad26 vector-based vaccine for SARS-CoV-2, termed Ad26.COV2.S, is currently being evaluated in clinical trials

    Effective curricula for at-risk students in vocational education:a study of teachers’ practice

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    Abstract Background This study focused upon a curriculum for at-risk students in vocational education aimed at enhancing students’ motivation and engagement for learning. The study explored teachers’ view on effective curricular characteristics and teachers’ strategies to create positive learning experiences for students. Methods Qualitative research has been conducted regarding four curricula for at-risk students; data were collected and examined by means of 16 focus group interviews with teachers and analysis of relevant documents. Results Teachers pointed out the central position of the student, resulting in individual trajectories. Teachers used peer group dynamics, job orientation and sports as tool for student development. Teachers regarded themselves as coaches, as experts in sport activities and as group managers. For positive learning experiences two key curricular characteristics have been identified: (1) equality in the relationship between student and teacher, (2) a positive fit between the curriculum and the students
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