12,643 research outputs found

    Dirac's hole theory versus quantum field theory

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    Dirac's hole theory and quantum field theory are usually considered equivalent to each other. For models of a certain type, however, the equivalence may not hold as we discuss in this Letter. This problem is closely related to the validity of the Pauli principle in intermediate states of perturbation theory.Comment: No figure

    RGMa and RGMb expression pattern during chicken development suggest unexpected roles for these repulsive guidance molecules in notochord formation, somitogenesis, and myogenesis

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    Background: Repulsive guidance molecules (RGM) are high-affinity ligands for the Netrin receptor Neogenin, and they are crucial for nervous system development including neural tube closure; neuronal and neural crest cell differentiation and axon guidance. Recent studies implicated RGM molecules in bone morphogenetic protein signaling, which regulates a variety of developmental processes. Moreover, a role for RGMc in iron metabolism has been established. This suggests that RGM molecules may play important roles in non-neural tissues. Results: To explore which tissues and processed may be regulated by RGM molecules, we systematically investigated the expression of RGMa and RGMb, the only RGM molecules currently known for avians, in the chicken embryo. Conclusions: Our study suggests so far unknown roles of RGM molecules in notochord, somite and skeletal muscle development. Developmental Dynamics, 2012. (C) 2012 Wiley Periodicals, Inc.AFMAFMCNPqCNPqFAPESPFAPES

    Dynamic changes in connexin expression correlate with key events in the wound healing process.

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    Wound healing is a complex process requiring communication for the precise co-ordination of different cell types. The role of extracellular communication through growth factors in the wound healing process has been extensively documented, but the role of direct intercellular communication via gap junctions has scarcely been investigated. We have examined the dynamics of gap junction protein (Connexins 26, 30, 31.1 and 43) expression in the murine epidermis and dermis during wound healing, and we show that connexin expression is extremely plastic between 6 hours and 12 days post-wounding. The immediate response (6 h) to wounding is to downregulate all connexins in the epidermis, but thereafter the expression profile of each connexin changes dramatically. Here, we correlate the changing patterns of connexin expression with key events in the wound healing process

    Betabloqueadores no Choque Séptico: Já Chegámos Lá?

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    info:eu-repo/semantics/publishedVersio

    Água e degradação do solo.

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    bitstream/item/26832/1/gua-e-degradaAEo-do-solo-Portal-Dia-de-Campo.pd
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