Características morfoagronômicas da BRS Platina sob níveis de sombreamento.

A bananeira é uma fruteira muito utilizada na composição de sistemas agroflorestais (SAFs) no Brasil e na América Latina. Sua escolha para integrar os SAFs vai além da produção de alimento rico em carboidratos, vitaminas e minerais

Serratia osteomyelitis and chronic granulomatous disease

Chronic Granulomatous Disease (CGD) is a primary immunodeficiency disorder characterized by recurrent purulent infections of the skin, lungs, and reticuloendothelial organs, primarily due to staphylococci, enteric bacteria, fungi, and occasionally mycobacteria. More than two thirds of all cases are X-linked and result from defects in the CYBB gene that encodes the gp91-phox subunit of NADPH oxidase. The authors present a case of a three month old child admitted with a metacarpic steomyelitis by Serratia marcescens. Studies confirmed an abnormal respiratory burst in activated neutrophils and absence of gp91-phox expression on patient and a brother (with previous Nocardia infection). Both hemizygous for a pathogenic mutation detected in exon 3 of CYBB gene (c.252 G>A, p.Ala84Ala), a variant that affects the splicing. At two years of age he is still on prophylaxis with cotrimoxazol and itraconazol, without relevant complications. CGD is rare but must be evocated in cases of uncommon or atypical infections

Electrochemical oxidation of tamoxifen revisited

Tamoxifen is a selective estrogen receptor modulator that is used as an adjuvant and/or chemotherapeutic agent for the treatment of all stages of hormone-dependent breast cancer. Currently there is a deep interest in the study of tamoxifen biotransformation and identification of metabolites since they can significantly contribute to the overall pharmacological or adverse effects of the drug. Accordingly, the study of the electrochemical behavior of tamoxifen in aqueous solution is reported. To clarify the occurring oxidative process and to assess the influence of the functional groups on the oxidation mechanism, the voltammetric assessment was extended to the study of tamoxifen’s analogues (E)-tamoxifen and dihydrotamoxifen, and to its main phase I oxidative metabolite, N-desmethyl tamoxifen. The data found shows that the oxidative processes occurring in tamoxifen are essentially related with the two chemical moieties present in the molecule: the substituted aromatic nucleus and the tertiary amine group. Moreover, the results obtained suggest that the ethylenic linkage is not critical for tamoxifen’s oxidation although it could play an important role in the course of the oxidation process. These results could contribute to highlight some remaining questions regarding tamoxifen’s metabolic behavior and to the development of new analytical strategies, based on electrochemical approaches

Avaliação de tetraplóides de bananeira cultivados em área infestada por mal-do-Panamá: segundo ciclo.

O mal-do-Panamá uma das mais importantes doenças da bananeira, causada pelo fungo Fusarium oxysporum f.sp. cubense, provoca elevadas perdas na produção. Esse trabalho teve como objetivo, avaliar, no segundo ciclo, as características agronômicas e a reação ao Fusarium de genótipos de bananeira. Foram avaliadas nove cultivares usando a Maçã como testemunha (suscetível), em delineamento inteiramente casualizado, com 10 repetições de uma planta. Avaliaram-se oito características agronômicas e a incidência de Fusarium. Há uma ampla variação genética para todos os caracteres agronômicos avaliados. Os híbridos de Prata Anã são superiores em produção aos de Pacovan. Os genótipos Porp, P.Jussara, Fhia-01 e PA94-01 são resistentes ao mal-do-Panamá.pdf 218

Obtenção de nanocelulose extraída das fibras do caroço de manga Tommy Atkins.

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