1,594 research outputs found
From videocassette to video stream: Issues involved in reāpurposing an existing educational video
Conventional video recordings can be converted into video streams but the process can be complex and problematic. The authorsā experience of reāpurposing an existing video, Back Care for Health Professionals, for streaming is used to illustrate what was involved and to highlight the important issues. Financial, legal, technical and pedagogic issues are examined
Accessing and engaging with video streams for educational purposes: experiences, issues and concerns
Video streaming has the potential to offer tutors a more flexible and accessible means of incorporating moving images into learning resources for their students than conventional video. Consideration is given to this assertion by drawing upon the experiences of staff and evidence from students at the University of Southampton in the use of a video, Back Care for Health Professionals, before and after it was streamed. The resulting case study highlights various issues and concerns, both logistical and pedagogic. These include ease of access, the form and frequency of guidance with respect to technical matters, the use of multiple channels of communication to convey key messages about the availability and value of the video, and the provision of demonstrations or 'tasters'. In other words, what some might regard as the 'softer' aspects of technological developments should receive at least as much attention as the 'harder'
Nicotine treatment decreases food intake and body weight via a leptin-independent pathway in Psammomys obesus
It has been reported previously that leptin may be involved in nicotine\u27s ability to reduce body weight. Our aim was to investigate whether the anorexic action of nicotine is related to the actions of leptin by utilizing lean leptin-sensitive and obese leptin-resistant Psammomys obesus. Lean and obese P. obesus were assigned to receive nicotine sulphate at 6, 9 or 12 mg/day or saline (control) for 9 days (n = 6-10 in each group), administered using mini-osmotic pumps. Food intake, body weight, plasma leptin concentrations, plasma insulin and blood glucose were measured at baseline and throughout the study period. Nicotine treatment reduced food intake by up to 40% in lean and obese P. obesus. Plasma leptin levels fell significantly only in lean nicotine-treated animals, whereas no changes were observed in obese nicotine-treated animals. However, both lean and obese nicotine-treated animals had similar reductions in body weight. Our results show that nicotine has dramatic effects on food intake and body weight, however, these changes appear to be independent of the leptin signalling pathway.<br /
Profiling the Organic Emissions from a Light-Duty Direct Injection Diesel Engine over a range of Speeds and Loads
Diesel engines account for a large percentage of the particulates in urban city environments. Polycyclic aromatic
compounds (PAC), some proven carcinogens, have been found on diesel particulates. The trace level nitro-PAC
emissions, such as 1-nitropyrene and dinitropyrenes, contribute a large proportion of the mutagenicity in the
particulates; in the case of 1-nitropyrene between 10 to 40% of the total mutagenicity of the particulate has been
claimed. The potential health hazards of PAC require the levels and sources of such emissions to be evaluated over
a range of speeds and loads.
PAC emissions are dependant on the engine specification, such as normally aspirated compared with turbocharged,
and the operating conditions (speed and load). The effect of such variables can be determined using emission
profiling, in which profiles of the exhaust are compared at varying engine powers. In this way the effect of speed and
load on the combustion efficiency can be established.
Identification of PAC sources may be further complicated when engine sampling systems, such as the conventional
dilution tunnel/filter system, are prone to artefact formation. This is especially relevant to secondary nitro-PAC
emissions, which are prone to forming as artefacts of the filter installed in the dilution tunnel. In this study, organic
emission maps were constructed using the unique total exhaust solvent-stripping apparatus (TESSA) developed at the
University of Plymouth. TESSA allowed rapid sampling with a minimum potential for artefact formation. The close
proximity of TESSA to the engine allowed the role of the combustion chamber in the formation of emissions to be
evaluated.
Primary organic emissions, such as pyrene, are derived from survival of compounds in the fuel/oil and by combustion
generation. Establishment of emission maps for the primary emissions are vital to resolving the formation of
secondary emissions, such as 1-nitropyrene. Profiling of primary emissions sampled 26 different speeds and loads
using TESSA (sampling times as low as IS seconds). Following simple work-up, quantification of the o-alkanes was
by gas chromatography with flame ionisation detection and PAH by gas chromatography/mass spectrometry operated
in electron impact mode. Emissions were expressed as a recovery of the compound emitted as a percentage of the
same compound entering the chamber in the fuel. The o-alkane and PAH emission maps correlated with the gaseous
unburnt hydrocarbon emissions, indicating that fuel survival was an important source of emissions, whereas
lubricating oil contributions were minimal. Fuel survival contributions decreased with load; at 1000 rpm the average
PAH survival of 0.95% at idling decreased to 0.2% at full load. High survivals under idling was a consequence of
the low chamber temperatures and air:fuel ratios mixed beyond the lean flammability limits, whereas at full load, the
high temperatures resulted in the greatest combustion efficiency. The o-alkane emission trends replicated those of
PAH; at 1000 rpm the average o-alkane survival was 0.48% at idle compared with 0.084% at full load. Correlations
between the distribution of the emissions and fuel at high load, suggested fuel survival unchanged was responsible.
At low loads the exhaust/fuel PAH ratios were more varied, with the range of percentage recoveries at low loads
increasing with speed (difference between percentage recovery of fluorene and phenanthrene at idling for 1000 rpm
and 3000 rpm was 0.05 and 0.18 respectively).
At high load, the combustion environment can be envisaged as producing areas under which complete combustion
and survival unchanged occur. In between the complete combustion and unburnt fuel zones, a narrow range of
temperatures and time for combustion reduce the opportunity for combustion generation reactions and/or preferential
survival. Low load at 3000 rpm may increase the intermediate zone, allowing preferential survival and/or combustion
generation reactions to evolve. Possible pyrolytic cracking of o-alkanes and demethylation of PAH at low loads and
3000 rpm was evident. The optimum time, swirl, and temperature for efficient combustion at low loads was generated
at 2000 rpm to 2500 rpm, whereas at the higher temperatures corresponding to high loads, the effect of speed was
much smaller. The primary emissions map show engineering improvements, particularly at low loads, could be
implemented to lower the PAH emissions. The correlation between the emissions and fuel input suggest modifications
to the PAH content of fuels may lower emissions.
The formation of secondary nitro- and oxy-PAC emissions is by transformation of primary emissions. In the case of
nitro-PAC, nitration has been proposed to occur by free radical processes between PAH and oxides of nitrogen, NO,,
within the chamber and by electrophilic substitution of PAH surviving combustion by nitrogen dioxide and nitric acid,
via the nitronium ion. The combustion contribution to nitro-PAC emissions was investigated using an upgraded
TESSA system, and 3 speeds at low, mid, and high NO, for each speed were sampled. Following initial extraction,
concentration and clean-up of the samples, the nitro-PAC fractions of interest were isolated by normal phase high
performance liquid chromatography. The nitro-PAC were identified and quantified by gas chromatography with
electron capture detection, and gas chromatography/mass spectrometry operated in the negative ion chemical
ionisation mode (the detection limits for both analytical systems was of the order of 40-50 pg of nitro-PAC standards
injected). The profiling indicated that a proportion of the fuel underwent nitration within the combustion chamber
across a range of speeds and loads. The extract concentrations (average of 5.3 ppm) found in this study were much
lower than those previous found (ranging from 55 to 2280 ppm). The majority of the previous studies relied on
sampling using dilution tunnel/filter systems, for which post combustion contributions are simulated; suggesting that
a major source of nitro-PAC is derived from post-combustion nitration of PAH surviving combustion, some of which
may be artefacts of the filter. Different speeds produced different trends for nitro-PAC emissions with respect to
engine load. It was not until the high temperature speed of 3500 rpm was reached that both NO, and nitro-PAC
increased with load (R-sq= 0.989 & p=0.067 for 1-nitronaphthalene & NO,).
Nitro-PAC emissions at 3500 rpm were primarily the result of combustion chamber nitration of PAH at high NO,.
In the case of 1-nitropyrene, there was strong evidence to support pyrosynthetic contributions to the pyrene mass,
which in turn became nitrated. The nitro-PAC emissions at low loads were the result of post-combustion nitration
of PAH surviving combustion with the nitronium ion. The correlation of the PAH precursors to nitro-PAC in the fuel
and nitro-PAC emissions suggest fuel modifications may to some extent lower the nitro-PAC emissions. The
combustion generation of nitro-PAC at high engine powers may require post-combustion after treatment.Perkins Technology, Peterboroug
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