38 research outputs found
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The Impact of Exploitation and Exploration on Export Sales Growth: The Moderating Role of Domestic and International Collaborations
This work is based on data from the U.K. Community Innovation Survey, produced by the Office for National Statistics, and supplied by the Secure Data Service at the U.K. Data Archive.This study examines the short- and long-term implications of the impact of exploitation and exploration on export sales growth. It also explores the moderating role of external collaborations by differentiating between domestic collaborations and international collaborations. The authors tested their conceptual model with data from the U.K. Community Innovation Survey (2010–2016). Using different time lags for exploitation and exploration, the findings indicate that the impact varies over time. Specifically, they reveal that the effect of exploitation is negative in the long term but positive in the short term, while exploration has no significant effect in the short term but a positive influence on export sales growth in the long term. Similarly, the moderating effect of domestic and international collaborations has been found to vary over time. The authors conclude with a discussion of the theoretical and practical implications.The author(s) received no financial support for the research, authorship, and/or publication of this article
Consolidating and advancing knowledge on the post-entry performance of international new ventures
This paper consolidates emerging evidence on factors influencing the post-entry performance of INVs. It also addresses the challenging question of how to effectively measure performance in the entrepreneurial internationalisation context. The discussion presents and reflects on empirical findings from the studies included in the current Special Issue on INVs’ post-entry performance, extends debates on the themes examined and performance measures employed, whilst also acknowledging issues requiring future investigation. Notably, the studies’ findings reinforce previous evidence on the performance-enhancing effects of exposure to diverse, extra-regional market. Support is also reported for the importance of learning capabilities, but the relevant study goes even further to show how these capabilities interact with INVs’ strategies and resources to enhance post-entry performance. INV setting is especially difficult for the performance measurement as internationalization requires resources and young age means that firms are early in their life-cycle and financial performance, for example, may not be relevant. The paper also addresses the issues associated with measuring post-entry performance among INVs and discusses next steps and future research implications
Antecedents and consequences of effectuation and causation in the international new venture creation process
The selection of the entry mode in an international market is of key importance for the venture. A process-based perspective on entry mode selection can add to the International Business and International Entrepreneurship literature. Framing the international market entry as an entrepreneurial process, this paper analyzes the antecedents and consequences of causation and effectuation in the entry mode selection. For the analysis, regression-based techniques were used on a sample of 65 gazelles. The results indicate that experienced entrepreneurs tend to apply effectuation rather than causation, while uncertainty does not have a systematic influence. Entrepreneurs using causation-based international new venture creation processes tend to engage in export-type entry modes, while effectuation-based international new venture creation processes do not predetermine the entry mod
Ex-post Performance Implications of Divergence of Managers’ Perceptions of ‘Distance’ From ‘Reality’ in International Business
Despite much research on “distance”, little attention has been paid to the effect of divergence of managers’ perceptions of distance from reality (i.e. distance divergence) and its implications for firm performance. This knowledge is highly important since managerial perceptions of the firm’s environment do not always coincide with the actual environmental characteristics. Consequently, strategies based on inaccurate data may result in erroneous forecasts, missed opportunities and business failure. Using survey data from senior managers of Swedish exporters and corresponding objective data, this study is a first attempt to explore the ex-post performance implications of “distance divergence” when expanding into foreign markets. Our results demonstrate that the larger the divergence between managers’ perceptions of cultural distance and corresponding “objective” distance, the lower the performance expressed in companies’ sales. However, over/underestimation of cultural distance does not have differential effects on firm performance.“Stiftelsen Olle Hakelius Stipendiefond”, Grant no: 1165001
In vivo evaluation of the hypoglycemic effect of wolf-apple flour (Solanum lycocarpum A. St.-Hil)
The prevalence of diabetes has increased at alarming rates worldwide, and has become a serious health problem in modern society, highlighting the need for adjuvants to assist in its treatment. The starch from wolf-apple is a product extracted from the pulp of the unripe wolf-apple (Solanum lycocarpum A. St.-Hil), which has been used empirically by the population due to various therapeutic effects, among them, its hypoglycemic action. The objective of this study was to evaluate the hypoglycemic effect of the administration of wolf-apple starch on diabetic Wistar rats, during five weeks. The animals were randomly divided into three groups: normal control, diabetic control and treated diabetic (received 100 mg/day of wolf-apple flour by gavage), and diabetes was induced with streptozotocin (40 mg/kg rat). The following parameters were evaluated: glycemia, animal weight, food intake, diuresis, water intake and histopathological analyses of liver and pancreas. The results show that the flour presented a hypoglycemic effect of 19.76%, and there was no significant difference in food consumption, water consumption and weight gain among the evaluated groups. On the other hand, the treated diabetic group showed a urine volume significantly higher than the other groups. The treated animals did not show toxicity in the liver and pancreas. It is concluded that the starch from wolf-apple has hypoglycemic potential.Keywords: Wolf-apple, flour, hypoglycemic effect, diabetes.African Journal of Biotechnology, Vol 13(31) 3302-330
Antinociceptive Activity of Thymoquinone and its Structural Analogues: A Structure-Activity Relationship Study
Purpose: To investigate the structural features that influence the
antinociceptive activity of thymoquinone and their structural
analogues. Methods: The quinones were prepared by an oxidation
procedure using molecular oxygen and catalysis with [CoII(salen)] from
the respective phenols. The antinociceptive activity of
para-benzoquinones (10 mg/kg, ip) was evaluated using formalin test in
mice. Vehicle (5 % Tween 80) or morphine (10 mg/kg) were used as
control group and standard drug, respectively. The amount of time spent
licking the injected paw was considered as the nociceptive response.
Results: Among the compounds tested, five para-benzoquinones showed
antinociceptive activity. The 2-isopropyl-para-benzoquinone presented
the highest potency in first and second phases and produced a
near-maximal inhibition (p < 0.001) in the formalin test, similar to
morphine (p < 0.001). Conclusion: Our experimental results show that
by appropriate structural modification of parabenzoquinones it may be
possible to develop novel analgesic drugs