23,589 research outputs found

    Flexural behaviours of Engineered Cementitious Composites – High strength steel composite beams

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    Since the compressive strain of normal strength concrete (NSC) (0.23 – 0.3%) is too low to work compatibly with high strength steel (HSS) with typical yield strain greater than 0.35%, Engineered Cementitious Composites (ECC) which generally has a minimum compressive strain of 0.5%, is an attractive alternative to replace NSC when constructing composite beams using HSS sections. This study investigated experimentally the flexural behaviours of composite beams comprising HSS I-section and hybrid Polyethylene-steel fibres (PE-ST) ECC slab. Shear interactions between the HSS beam and the PE-ST ECC slab was provided by normal profiled steel sheeting (PSS) and headed shear studs. Four composite beams including three ECC-HSS beams and one NSC-HSS beam were tested under four-point bending until failure. The test results indicated that while the flexural capacity of ECC-HSS beams only showed a slight improvement, its ductility was significantly enhanced when comparing with the NSC-HSS beam. All ECC-HSS beams failed in a ductile manner and gradual softening behaviours were observed after the peak load. In contrast, the NSC-HSS beam showed a less ductile failure mode with a sudden crushing of NSC and a sharp drop of bending resistance after the peak load. To complement the test results, a 3D nonlinear finite element (FE) model was also developed and validated against the experimental results. Well agreements between the FE and test results were observed. This confirmed that the FE model could be employed to evaluate the general behaviours of ECC-HSS composite beams

    Glycodelin suppresses endometrial cell migration and invasion but stimulates spheroid attachment

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    Glycodelin contains four isoforms with diverse biological functions. Glycodelin-A is potentially a diagnostic marker for cancer patients and receptivity marker of the secretory endometrium. Yet, direct evidence for the role of glycodelin in the regulation of endometrial epithelial cell migration, invasion and attachment of trophoblastic spheroids (blastocyst surrogate) is lacking. In this study, the human glycodelin gene was stably transfected into human endometrial (HEC1-B) cells. Forced expression of glycodelin in HEC1-B cells did not affect cell proliferation, cell viability or cell-cycle progression, but significantly reduced migration and invasion of the stably transfected cells (both P < 0.05). The migration rate returned to normal levels when the glycodelin-forced-expressing HEC1-B cells were treated with glycodelin RNAi. Furthermore, forced expression of glycodelin in HEC1-B cells significantly increased the attachment of trophoblastic spheroids onto the endometrial epithelial cells (P < 0.05). In summary, glycodelin suppressed endometrial cell migration and invasion but enhanced spheroid attachment. © 2012, Reproductive Healthcare Ltd.postprin

    Typical collapse modes of confined masonry buildings under strong earthquake loads

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    Confined masonry structures are a widely applied structural system in many developing countries. During the past Wenchuan Earthquake in 2008, numerous confined masonry buildings collapsed, while many others suffered damage. This study reviews the construction practices of confined masonry buildings in China. Simple models and hand calculation methods are proposed for quantifying the tearing failure of diaphragms, the tensile failure of tie-columns and the sway-mode strength of masonry buildings. The results indicate very good agreement with field observations. The seismic measures that are stipulated in the seismic design codes are very effective for increasing the strength and integrity, but not the ductility of masonry buildings. For those buildings that survived the earthquake, strength rather than ductility protected the confined masonry from collapse or serious damage. Design recommendations are suggested for preventing various types of premature failures and enhancing the lateral strength of masonry buildings. © Su et al.published_or_final_versio

    High performance communication subsystem for clustering standard high-volume servers using Gigabit Ethernet

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    This paper presents an efficient communication subsystem, DP-II, for clustering standard high-volume (SHV) servers using Gigabit Ethernet. The DP-II employs several lightweight messaging mechanisms to achieve low-latency and high-bandwidth communication. The test shows an 18.32 us single-trip latency and 72.8 MB/s bandwidth on a Gigabit Ethernet network for connecting two Dell PowerEdge 6300 Quad Xeon SMP servers running Linux. To improve the programmability of the DP-II communication subsystem, the development of DP-II was based on a concise yet powerful abstract communication model, Directed Point Model, which can be conveniently used to depict the inter-process communication pattern of a parallel task in the cluster environment. In addition, the API of DP-II preserves the syntax and semantics of traditional UNIX I/O operations, which make it easy to use.published_or_final_versio

    Machine scheduling with deliveries to multiple customer locations

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    Department of Logistics, Faculty of Business2005-2006 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

    Evaluation of Local & Global Ductility Relationships for Low-Rise Masonry-Infilled Reinforced Concrete Frame Structures

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    The paper presents the findings on a parametric study of the period lengthening effects of low-rise masonryinfilled reinforced concrete frame buildings using an incremental dynamic analysis (IDA). Simplified 2D building models utilizing Bouc-Wen model for describing strength, stiffness degradation and pinching effect were subjected to some selected ground motion records ranging from far to near field earthquakes in low to high seismicity regions. Simple equations correlating local to global ductilities derived from pushover (PO) analysis for buildings under soft storey failure mechanism are proposed. The equations take into account the governing factors like critical interstorey drift and number of storeys. The applicability of the equations was verified up to 7-storey buildings from the results of IDA. Such simple ductility relationships are likely to facilitate mostly the coefficient-based method, in which the typical PO analysis may be bypassed and allows making intuitive insight into the seismic performance of buildings.published_or_final_versio

    Severe ileitis associated with capecitabine: Two case reports and review of the literature

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    EBRT And HDRBT in Rectal Cancer Patients Who Are Medically Unfit Or Refuse Surgery

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    The Contribution of Ageing to Hospitalisation Days in Hong Kong: A Decomposition Analysis

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