37 research outputs found
Conformational analysis of coordination compounds. VII. Barrier to inversion of five-membered diamine chelate rings by N.M.R
Cystic macular oedema on spectral-domain optical coherence tomography in choroideremia patients without cystic changes on fundus examination
Purpose:
To determine the prevalence of cystic macular edema (CME) in patients with choroideremia by using spectral-domain optical coherence tomography (SD-OCT).
Methods:
Sixteen patients affected with choroideremia were enrolled in the study. All patients underwent a complete eye examination. SD-OCT was performed using an OPKO spectral-domain OCT/SLO instrument.
Results:
The average age of the study patients was 44.0 ± 16.0 years (range, 13-63 years). Out of the 16 patients with choroideremia, 10 patients (62.5%) showed a degree of CME on SD-OCT testing in at least one eye, and 8 patients (50%) showed CME in both eyes.
Conclusions:
Because of its notable prevalence, it would seem prudent to screen choroideremia patients by SD-OCT for the possible presence of CME and to identify those amenable to future treatment strategies for their macular edema