77,548 research outputs found

    Identity, environment and mental wellbeing in the veterinary profession

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    Mental health and career dissatisfaction are of increasing concern to the veterinary profession. The influence of identity on the psychological wellbeing of veterinarians has not been widely explored. Twelve recent veterinary graduates were enrolled in a private social media discussion group, and their identities investigated through narrative inquiry: a methodology which enables identity priorities to be extrapolated from stories of experience. Two distinct variants of the veterinary identity were identified: an academic, ‘diagnosis-focused’ identity, which prioritised definitive diagnosis and best-evidence treatment; and a broader ‘challenge-focused’ identity, where priorities additionally included engaging with the client, challenging environment or veterinary business. Contextual challenges (such as a client with limited finances or difficult interpersonal interactions) were seen as a source of frustration for those with a diagnosis-focused identity, as they obstructed the realisation of identity goals. Overcoming these challenges provided satisfaction to those with a challenge-focused identity. The employment environment of the graduates (general veterinary practice) provided more opportunities for those with a challenge-focused identity to realise identity goals, and more markers of emotional wellbeing were apparent in their stories. Markers of poor emotional health were evident in the stories of those with a diagnosis-focused identity

    Thrust chamber performance using Navier-Stokes solution

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    The viscous, axisymmetric flow in the thrust chamber of the space shuttle main engine (SSME) was computed on the CRAY 205 computer using the general interpolants method (GIM) code. Results show that the Navier-Stokes codes can be used for these flows to study trends and viscous effects as well as determine flow patterns; but further research and development is needed before they can be used as production tools for nozzle performance calculations. The GIM formulation, numerical scheme, and computer code are described. The actual SSME nozzle computation showing grid points, flow contours, and flow parameter plots is discussed. The computer system and run times/costs are detailed

    The Neural Encoding of Cocaine-Induced Devaluation in The Ventral Pallidum

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    Cocaine experience affects motivation structures such as the nucleus accumbens (NAc) and its major output target, the ventral pallidum (VP). Previous studies demonstrated that both NAc activity and hedonic responses change reliably as a taste cue comes to predict cocaine availability. Here we extended this investigation to examine drug-experience induced changes in hedonic encoding in the VP. VP activity was first characterized in adult male Sprague–Dawley rats in response to intraoral infusions of palatable saccharin and unpalatable quinine solutions. Next, rats received 7 daily pairings of saccharin that predicted either a cocaine (20 mg/kg, ip) or saline injection. Finally, the responses to saccharin and quinine were again assessed. Of 109 units recorded in 11 rats that received saccharin–cocaine pairings, 71% of responsive units significantly reduced firing rate during saccharin infusions and 64% increased firing rate during quinine exposure. However, as saccharin came to predict cocaine, and elicited aversive taste reactivity, VP responses changed to resemble quinine. After conditioning, 70% of saccharin-responsive units increased firing rate. Most units that encoded the palatable taste (predominantly reduced firing rate) were located in the anterior VP, while most units that were responsive to aversive tastes were located in the posterior VP. This study reveals an anatomical complexity to the nature of hedonic encoding in the VP

    Profitable Scheduling on Multiple Speed-Scalable Processors

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    We present a new online algorithm for profit-oriented scheduling on multiple speed-scalable processors. Moreover, we provide a tight analysis of the algorithm's competitiveness. Our results generalize and improve upon work by \textcite{Chan:2010}, which considers a single speed-scalable processor. Using significantly different techniques, we can not only extend their model to multiprocessors but also prove an enhanced and tight competitive ratio for our algorithm. In our scheduling problem, jobs arrive over time and are preemptable. They have different workloads, values, and deadlines. The scheduler may decide not to finish a job but instead to suffer a loss equaling the job's value. However, to process a job's workload until its deadline the scheduler must invest a certain amount of energy. The cost of a schedule is the sum of lost values and invested energy. In order to finish a job the scheduler has to determine which processors to use and set their speeds accordingly. A processor's energy consumption is power \Power{s} integrated over time, where \Power{s}=s^{\alpha} is the power consumption when running at speed ss. Since we consider the online variant of the problem, the scheduler has no knowledge about future jobs. This problem was introduced by \textcite{Chan:2010} for the case of a single processor. They presented an online algorithm which is αα+2eα\alpha^{\alpha}+2e\alpha-competitive. We provide an online algorithm for the case of multiple processors with an improved competitive ratio of αα\alpha^{\alpha}.Comment: Extended abstract submitted to STACS 201

    Dynamic Set Intersection

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    Consider the problem of maintaining a family FF of dynamic sets subject to insertions, deletions, and set-intersection reporting queries: given S,SFS,S'\in F, report every member of SSS\cap S' in any order. We show that in the word RAM model, where ww is the word size, given a cap dd on the maximum size of any set, we can support set intersection queries in O(dw/log2w)O(\frac{d}{w/\log^2 w}) expected time, and updates in O(logw)O(\log w) expected time. Using this algorithm we can list all tt triangles of a graph G=(V,E)G=(V,E) in O(m+mαw/log2w+t)O(m+\frac{m\alpha}{w/\log^2 w} +t) expected time, where m=Em=|E| and α\alpha is the arboricity of GG. This improves a 30-year old triangle enumeration algorithm of Chiba and Nishizeki running in O(mα)O(m \alpha) time. We provide an incremental data structure on FF that supports intersection {\em witness} queries, where we only need to find {\em one} eSSe\in S\cap S'. Both queries and insertions take O\paren{\sqrt \frac{N}{w/\log^2 w}} expected time, where N=SFSN=\sum_{S\in F} |S|. Finally, we provide time/space tradeoffs for the fully dynamic set intersection reporting problem. Using MM words of space, each update costs O(MlogN)O(\sqrt {M \log N}) expected time, each reporting query costs O(NlogNMop+1)O(\frac{N\sqrt{\log N}}{\sqrt M}\sqrt{op+1}) expected time where opop is the size of the output, and each witness query costs O(NlogNM+logN)O(\frac{N\sqrt{\log N}}{\sqrt M} + \log N) expected time.Comment: Accepted to WADS 201

    Modeling of secondary organic aerosol yields from laboratory chamber data

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    Laboratory chamber data serve as the basis for constraining models of secondary organic aerosol (SOA) formation. Current models fall into three categories: empirical two-product (Odum), product-specific, and volatility basis set. The product-specific and volatility basis set models are applied here to represent laboratory data on the ozonolysis of α-pinene under dry, dark, and low-NOx conditions in the presence of ammonium sulfate seed aerosol. Using five major identified products, the model is fit to the chamber data. From the optimal fitting, SOA oxygen-to-carbon (O/C) and hydrogen-to-carbon (H/C) ratios are modeled. The discrepancy between measured H/C ratios and those based on the oxidation products used in the model fitting suggests the potential importance of particle-phase reactions. Data fitting is also carried out using the volatility basis set, wherein oxidation products are parsed into volatility bins. The product-specific model is most likely hindered by lack of explicit inclusion of particle-phase accretion compounds. While prospects for identification of the majority of SOA products for major volatile organic compounds (VOCs) classes remain promising, for the near future empirical product or volatility basis set models remain the approaches of choice

    Studies related to primitive chemistry. A proton and nitrogen-14 nuclear magnetic resonance amino acid and nucleic acid constituents and a and their possible relation to prebiotic

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    Preliminary proton nuclear magnetic resonance (NMR) studies were made to determine the applicability of this technique for the study of interactions between monomeric and polymeric amino acids with monomeric nucleic acid bases and nucleotides. Proton NMR results for aqueous solutions (D2O) demonstrated interactions between the bases cytosine and adenine and acidic and aromatic amino acids. Solutions of 5'-AMP admixed with amino acids exhibited more complex behavior but stacking between aromatic rings and destacking at high amino acids concentration was evident. The multisite nature of 5'-AMP was pointed out. Chemical shift changes for adenine and 5'-AMP with three water soluble polypeptides demonstrated that significant interactions exist. It was found that the linewidth-pH profile of each amino acid is unique. It is concluded that NMR techniques can give significant and quantitative data on the association of amino acid and nucleic acid constituents

    Space shuttle contamination due to backflow from control motor exhaust

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    Spacecraft contamination of the space shuttle orbiter and accompanying Spacelab payloads is studied. The scattering of molecules from the vernier engines and flash evaporator nozzle after impingement on the orbiter wing surfaces, and the backflow of molecules out of the flash evaporator nozzle plume flow field due to intermolecular collisions in the plume are the problems discussed. A method was formulated for dealing with these problems, and detailed results are given
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