97 research outputs found

    Technique for continuous bedside monitoring of the global cerebral energy state

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    Accurate masses and radii of normal stars: modern results and applications

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    This paper presents and discusses a critical compilation of accurate, fundamental determinations of stellar masses and radii. We have identified 95 detached binary systems containing 190 stars (94 eclipsing systems, and alpha Centauri) that satisfy our criterion that the mass and radius of both stars be known to 3% or better. To these we add interstellar reddening, effective temperature, metal abundance, rotational velocity and apsidal motion determinations when available, and we compute a number of other physical parameters, notably luminosity and distance. We discuss the use of this information for testing models of stellar evolution. The amount and quality of the data also allow us to analyse the tidal evolution of the systems in considerable depth, testing prescriptions of rotational synchronisation and orbital circularisation in greater detail than possible before. The new data also enable us to derive empirical calibrations of M and R for single (post-) main-sequence stars above 0.6 M(Sun). Simple, polynomial functions of T(eff), log g and [Fe/H] yield M and R with errors of 6% and 3%, respectively. Excellent agreement is found with independent determinations for host stars of transiting extrasolar planets, and good agreement with determinations of M and R from stellar models as constrained by trigonometric parallaxes and spectroscopic values of T(eff) and [Fe/H]. Finally, we list a set of 23 interferometric binaries with masses known to better than 3%, but without fundamental radius determinations (except alpha Aur). We discuss the prospects for improving these and other stellar parameters in the near future.Comment: 56 pages including figures and tables. To appear in The Astronomy and Astrophysics Review. Ascii versions of the tables will appear in the online version of the articl

    A Model for the Detection of Moving Targets in Visual Clutter Inspired by Insect Physiology

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    We present a computational model for target discrimination based on intracellular recordings from neurons in the fly visual system. Determining how insects detect and track small moving features, often against cluttered moving backgrounds, is an intriguing challenge, both from a physiological and a computational perspective. Previous research has characterized higher-order neurons within the fly brain, known as ‘small target motion detectors’ (STMD), that respond robustly to moving features, even when the velocity of the target is matched to the background (i.e. with no relative motion cues). We recorded from intermediate-order neurons in the fly visual system that are well suited as a component along the target detection pathway. This full-wave rectifying, transient cell (RTC) reveals independent adaptation to luminance changes of opposite signs (suggesting separate ON and OFF channels) and fast adaptive temporal mechanisms, similar to other cell types previously described. From this physiological data we have created a numerical model for target discrimination. This model includes nonlinear filtering based on the fly optics, the photoreceptors, the 1st order interneurons (Large Monopolar Cells), and the newly derived parameters for the RTC. We show that our RTC-based target detection model is well matched to properties described for the STMDs, such as contrast sensitivity, height tuning and velocity tuning. The model output shows that the spatiotemporal profile of small targets is sufficiently rare within natural scene imagery to allow our highly nonlinear ‘matched filter’ to successfully detect most targets from the background. Importantly, this model can explain this type of feature discrimination without the need for relative motion cues

    Injection-site reactions upon Kineret (anakinra) administration: experiences and explanations

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    Anakinra (Kineret), a recombinant form of human interleukin-1 (IL-1) receptor antagonist, is approved for the treatment of rheumatoid arthritis (RA) in combination with methotrexate. Kineret is self-administered by daily subcutaneous injections in patients with active RA. The mechanism of action of anakinra is to competitively inhibit the local inflammatory effects of IL-1. Kineret is generally safe and well tolerated and the only major treatment-related side effects that appear are skin reactions at the injection site. Due to the relatively short half-life of anakinra, daily injection of the drug is required. This, in combination with the comparably high rates of injection-site reactions (ISRs) associated with the drug, can become a problem for the patient. The present review summarises published data concerning ISRs associated with Kineret and provides some explanations as to their cause. The objective is also to present some clinical experiences of how the ISRs can be managed

    Static-Memory-Hard Functions, and Modeling the Cost of Space vs. Time

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    A series of recent research starting with (Alwen and Serbinenko, STOC 2015) has deepened our understanding of the notion of memory-hardness in cryptography — a useful property of hash functions for deterring large-scale password-cracking attacks — and has shown memory-hardness to have intricate connections with the theory of graph pebbling. Definitions of memory-hardness are not yet unified in the somewhat nascent field of memory-hardness, however, and the guarantees proven to date are with respect to a range of proposed definitions. In this paper, we observe two significant and practical considerations that are not analyzed by existing models of memory-hardness, and propose new models to capture them, accompanied by constructions based on new hard-to-pebble graphs. Our contribution is two-fold, as follows. First, existing measures of memory-hardness only account for dynamic memory usage (i.e., memory read/written at runtime), and do not consider static memory usage (e.g., memory on disk). Among other things, this means that memory requirements considered by prior models are inherently upper-bounded by a hash function’s runtime; in contrast, counting static memory would potentially allow quantification of much larger memory requirements, decoupled from runtime. We propose a new definition of static-memory-hard function (SHF) which takes static memory into account: we model static memory usage by oracle access to a large preprocessed string, which may be considered part of the hash function description. Static memory requirements are complementary to dynamic memory requirements: neither can replace the other, and to deter large-scale password-cracking attacks, a hash function will benefit from being both dynamic memory-hard and static-memory-hard. We give two SHF constructions based on pebbling. To prove static-memory-hardness, we define a new pebble game (“black-magic pebble game”), and new graph constructions with optimal complexity under our proposed measure. Moreover, we provide a prototype implementation of our first SHF construction (which is based on pebbling of a simple “cylinder” graph), providing an initial demonstration of practical feasibility for a limited range of parameter settings. Secondly, existing memory-hardness models implicitly assume that the cost of space and time are more or less on par: they consider only linear ratios between the costs of time and space. We propose a new model to capture nonlinear time-space trade-offs: e.g., how is the adversary impacted when space is quadratically more expensive than time? We prove that nonlinear tradeoffs can in fact cause adversaries to employ different strategies from linear tradeoffs. Finally, as an additional contribution of independent interest, we present an asymptotically tight graph construction that achieves the best possible space complexity up to log log n-factors for an existing memory-hardness measure called cumulative complexity in the sequential pebbling model

    Constraining the electric charges of some astronomical bodies in Reissner-Nordstrom spacetimes and generic r^-2-type power-law potentials from orbital motions

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    We put model-independent, dynamical constraints on the net electric charge Q of some astronomical and astrophysical objects by assuming that their exterior spacetimes are described by the Reissner-Nordstroem metric, which induces an additional potential U_RN \propto Q^2 r^-2. Our results extend to other hypothetical power-law interactions inducing extra-potentials U_pert = r^-2 as well (abridged).Comment: LaTex2e, 16 pages, 3 figures, no tables, 128 references. Version matching the one at press in General Relativity and Gravitation (GRG). arXiv admin note: substantial text overlap with arXiv:1112.351

    Dynamics of Disks and Warps

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    This chapter reviews theoretical work on the stellar dynamics of galaxy disks. All the known collective global instabilities are identified, and their mechanisms described in terms of local wave mechanics. A detailed discussion of warps and other bending waves is also given. The structure of bars in galaxies, and their effect on galaxy evolution, is now reasonably well understood, but there is still no convincing explanation for their origin and frequency. Spiral patterns have long presented a special challenge, and ideas and recent developments are reviewed. Other topics include scattering of disk stars and the survival of thin disks.Comment: Chapter accepted to appear in Planets, Stars and Stellar Systems, vol 5, ed G. Gilmore. 32 pages, 17 figures. Includes minor corrections made in proofs. Uses emulateapj.st

    The Confrontation between General Relativity and Experiment

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    The status of experimental tests of general relativity and of theoretical frameworks for analysing them is reviewed. Einstein's equivalence principle (EEP) is well supported by experiments such as the Eotvos experiment, tests of special relativity, and the gravitational redshift experiment. Future tests of EEP and of the inverse square law are searching for new interactions arising from unification or quantum gravity. Tests of general relativity at the post-Newtonian level have reached high precision, including the light deflection, the Shapiro time delay, the perihelion advance of Mercury, and the Nordtvedt effect in lunar motion. Gravitational-wave damping has been detected in an amount that agrees with general relativity to better than half a percent using the Hulse-Taylor binary pulsar, and other binary pulsar systems have yielded other tests, especially of strong-field effects. When direct observation of gravitational radiation from astrophysical sources begins, new tests of general relativity will be possible.Comment: 89 pages, 8 figures; an update of the Living Review article originally published in 2001; final published version incorporating referees' suggestion
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