236 research outputs found
Homogeneous Photometry VI: Variable Stars in the Leo I Dwarf Spheroidal Galaxy
We have characterized the pulsation properties of 164 candidate RR Lyrae
variables (RRLs) and 55 candidate Anomalous and/or short-period Cepheids in Leo
I dwarf spheroidal galaxy. On the basis of its RRLs Leo I is confirmed to be an
Oosterhoff-intermediate type galaxy, like several other dwarfs. We show that in
their pulsation properties, the RRLs representing the oldest stellar population
in the galaxy are not significantly different from those of five other nearby,
isolated dwarf spheroidal galaxies. A similar result is obtained when comparing
them to RR Lyrae stars in recently discovered ultra-faint dwarf galaxies. We
are able to compare the period distributions and period-amplitude relations for
a statistically significant sample of ab type RR Lyrae stars in dwarf galaxies
(~1300stars) with those in the Galactic halo field (~14,000stars) and globular
clusters (~1000stars). Field RRLs show a significant change in their period
distribution when moving from the inner (dG14kpc)
halo regions. This suggests that the halo formed from (at least) two dissimilar
progenitors or types of progenitor. Considered together, the RRLs in classical
dwarf spheroidal and ultra-faint dwarf galaxies-as observed today-do not appear
to follow the well defined pulsation properties shown by those in either the
inner or the outer Galactic halo, nor do they have the same properties as RRLs
in globular clusters. In particular, the samples of fundamental-mode RRLs in
dwarfs seem to lack High Amplitudes and Short Periods ("HASP":AV>1.0mag and P
<0.48d) when compared with those observed in the Galactic halo field and
globular clusters. The observed properties of RRLs do not support the idea that
currently existing classical dwarf spheroidal and ultra-faint dwarf galaxies
are surviving representative examples of the original building blocks of the
Galactic halo.Comment: 49 pages in referee format, 12 figure
Studying relationships between environment and malaria incidence in Camopi (French Guiana) through the objective selection of buffer-based landscape characterisations
<p>Abstract</p> <p>Background</p> <p>Malaria remains a major health problem in French Guiana, with a mean of 3800 cases each year. A previous study in Camopi, an Amerindian village on the Oyapock River, highlighted the major contribution of environmental features to the incidence of malaria attacks. We propose a method for the objective selection of the best multivariate peridomestic landscape characterisation that maximises the chances of identifying relationships between environmental features and malaria incidence, statistically significant and meaningful from an epidemiological point of view.</p> <p>Methods</p> <p>A land-cover map, the hydrological network and the geolocalised inhabited houses were used to characterise the peridomestic landscape in eleven discoid buffers with radii of 50, 100, 200, 300, 400, 500, 600, 700, 800, 900 and 1000 metres. Buffer-based landscape characterisations were first compared in terms of their capacity to discriminate between sites within the geographic space and of their effective multidimensionality in variable space. The Akaike information criterion (AIC) was then used to select the landscape model best explaining the incidences of <it>P. vivax </it>and <it>P. falciparum </it>malaria. Finally, we calculated Pearson correlation coefficients for the relationships between environmental variables and malaria incidence, by species, for the more relevant buffers.</p> <p>Results</p> <p>The optimal buffers for environmental characterisation had radii of 100 m around houses for <it>P. vivax </it>and 400 m around houses for <it>P. falciparum</it>. The incidence of <it>P. falciparum </it>malaria seemed to be more strongly linked to environmental features than that of <it>P. vivax </it>malaria, within these buffers. The incidence of <it>P. falciparum </it>malaria in children was strongly correlated with proportions of bare soil (r = -0.69), land under high vegetation (r = 0.68) and primary forest (r = 0.54), landscape division (r = 0.48) and the number of inhabited houses (r = -0.60). The incidence of <it>P. vivax </it>malaria was associated only with landscape division (r = 0.49).</p> <p>Conclusions</p> <p>The proposed methodology provides a simple and general framework for objective characterisation of the landscape to account for field observations. The use of this method enabled us to identify different optimal observation horizons around houses, depending on the <it>Plasmodium </it>species considered, and to demonstrate significant correlations between environmental features and the incidence of malaria.</p
Severe Acquired Toxoplasmosis Caused by Wild Cycle of Toxoplasma gondii, French Guiana
From 1998 through 2006, 44 cases of severe primary toxoplasmosis were observed in French Guiana in immunocompetent adults. Toxoplasma gondii isolates exhibited an atypical multilocus genotype. Severe disease in humans may result from poor host adaptation to neotropical zoonotic strains of T. gondii circulating in a forest-based cycle
Determination of the Plasmodium vivax relapse pattern in Camopi, French Guiana
<p>Abstract</p> <p>Background</p> <p>Malaria is a major public health problem in French Guiana, where <it>Plasmodium vivax </it>has become the dominant malaria species since 2000. As in others endemic areas, it is important to specify the pattern of vivax malaria relapses and to try to discriminate efficiently re-infections from relapses.</p> <p>Methods</p> <p>This study was conducted in children born between January 1, 2001 and December 31, 2008 in Camopi, an Amerindian village located in the Amazon forest (n = 325), using an open cohort design. Primary and secondary attack rates of <it>P. vivax </it>were calculated using survival analysis. With the difference between the primary and secondary rates, this study aimed to estimate indirectly <it>P. vivax </it>relapse rate and evaluate its time evolution.</p> <p>Results</p> <p>Of the 1042 malaria attacks recorded, 689 (66%) were due to <it>P. vivax </it>(without mixed infection). One hundred and fifty one children had their primary attack with <it>P. vivax </it>and 106 had their two first attacks with <it>P. vivax</it>. In the absence of primaquine treatment, it was shown that <it>P. vivax </it>relapses mainly occurred during the first three months after the first attack. Thirty percent of children never had a relapse, 42% had a relapse before the first month after primary attack, 59% before the second month and 63% before the third month.</p> <p>Conclusion</p> <p>This study confirmed that the relapse pattern in Camopi was compatible with the pattern described for the <it>P. vivax </it>Chesson (tropical) strain. In addition, due to the relapse rate time evolution, a simple arbitrary classification rule could be constructed: before 90 days after the primary attack, the secondary attack is a relapse; after 90 days, it is a re-infection. Adapted management of malaria cases based on these results could be devised.</p
Environmental, entomological, socioeconomic and behavioural risk factors for malaria attacks in Amerindian children of Camopi, French Guiana
<p>Abstract</p> <p>Background</p> <p>Malaria is a major health issue in French Guiana. Amerindian communities remain the most affected. A previous study in Camopi highlighted the predominant role of environmental factors in the occurrence of malaria. However, all parameters involved in the transmission were not clearly identified. A new survey was conducted in order to clarify the risk factors for the presence of malaria cases in Camopi.</p> <p>Methods</p> <p>An open cohort of children under seven years of age was set up on the basis of biologically confirmed malaria cases for the period 2001-2009. Epidemiological and observational environmental data were collected using two structured questionnaires. Data were analysed with a multiple failures multivariate Cox model. The influence of climate and the river level on malaria incidence was evaluated by time-series analysis. Relationships between <it>Anopheles darlingi </it>human biting rates and malaria incidence rates were estimated using Spearman's rank correlation.</p> <p>Results</p> <p>The global annual incidence over the nine-year period was 238 per 1,000 for <it>Plasmodium falciparum</it>, 514 per 1,000 for <it>Plasmodium visa </it>and 21 per 1,000 for mixed infections. The multivariate survival analysis associated higher malaria incidence with living on the Camopi riverside vs. the Oyapock riverside, far from the centre of the Camopi hamlet, in a home with numerous occupants and going to sleep late. On the contrary, living in a house cleared of all vegetation within 50 m and at high distance of the forest were associated with a lower risk. Meteorological and hydrological characteristics appeared to be correlated with malaria incidence with different lags. <it>Anopheles darlingi </it>human biting rate was also positively correlated to incident malaria in children one month later.</p> <p>Conclusions</p> <p>Malaria incidence in children remains high in young children despite the appearance of immunity in children around three years of age. The closeness environment but also the meteorological parameters play an important role in malaria transmission among children under seven years of age in Camopi.</p
Malaria or kalimbe: how to choose?
Should the Kalimbe (a traditional Amerindian loincloth) be banned, based on its association with an increased risk of malaria? Studies on malaria conducted on Amerindian children in the Oyapock region, French Guiana suggest that there is an argument for replacing the Kalimbe with a modern alternative. However, the wider issue of how the positive (risk reduction and related benefits) and negative effects (exacerbation of acculturation processes and associated consequences) should be assessed needs to be considered before suggesting a change in ancestral behaviour for medical purposes. A multidisciplinary approach is needed, together with caution and humility from epidemiologists
The ACS LCID project. IX. Imprints of the early Universe in the radial variation of the star formation history of dwarf galaxies
Based on Hubble Space Telescope observations from the Local Cosmology from
Isolated Dwarfs project, we present the star formation histories, as a function
of galactocentric radius, of four isolated Local Group dwarf galaxies: two dSph
galaxies, Cetus and Tucana, and two transition galaxies (dTrs), LGS-3 and
Phoenix. The oldest stellar populations of the dSphs and dTrs are, within the
uncertainties, coeval () at all galactocentric radii. We find that
there are no significative differences between the four galaxies in the
fundamental properties (such as the normalized star formation rate or
age-metallicity relation) of their outer regions (radii greater than four
exponential scale lengths); at large radii, these galaxies consist exclusively
of old () metal-poor stars. The duration of star formation in
the inner regions vary from galaxy to galaxy, and the extended central star
formation in the dTrs produces the dichotomy between dSph and dTr galaxy types.
The dTr galaxies show prominent radial stellar population gradients: the
centers of these galaxies host young () populations while the age
of the last formation event increases smoothly with increasing radius. This
contrasts with the two dSph galaxies. Tucana shows a similar, but milder,
gradient, but no gradient in age is detected Cetus. For the three galaxies with
significant stellar population gradients, the exponential scale length
decreases with time. These results are in agreement with outside-in scenarios
of dwarf galaxy evolution, in which a quenching of the star formation toward
the center occurs as the galaxy runs out of gas in the outskirts.Comment: Accepted to be published in Ap
The ACS LCID Project XI. On the early time resolution of LG dwarf galaxy SFHs: Comparing the effects of reionization in models with observations
The analysis of the early star formation history (SFH) of nearby galaxies,
obtained from their resolved stellar populations is relevant as a test for
cosmological models. However, the early time resolution of observationally
derived SFHs is limited by several factors. Thus, direct comparison of
observationally derived SFHs with those derived from theoretical models of
galaxy formation is potentially biased. Here we investigate and quantify this
effect. For this purpose, we analyze the duration of the early star formation
activity in a sample of four Local Group dwarf galaxies and test whether they
are consistent with being true fossils of the pre-reionization era; i.e., if
the quenching of their star formation occurred before cosmic reionization by UV
photons was completed. Two classical dSph (Cetus and Tucana) and two dTrans
(LGS-3 and Phoenix) isolated galaxies with total stellar masses between
to M have been studied. Accounting
for time resolution effects, the SFHs peak as much as 1.25 Gyr earlier than the
optimal solutions. Thus, this effect is important for a proper comparison of
model and observed SFHs. It is also shown that none of the analyzed galaxies
can be considered a true-fossil of the pre-reionization era, although it is
possible that the {\it outer regions} of Cetus and Tucana are consistent with
quenching by reionization.Comment: To be published by the Ap
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