214 research outputs found

    Busca por similaridade em índice invertido utilizando o framework Hadoop Map-Reduce

    Get PDF
    Na área de Recuperação de Informação, é comum o uso de índices invertidos em sistemas que realizam a busca de objetos armazenados através de consultas compostas por palavras chave (termos). Nesse contexto, a busca por similaridade representa uma estratégia poderosa, uma vez que permite arecuperação de objetos que não seriam recuperados se fosse empregada a busca por equivalência. Contudo, a quantidade de objetos armazenados, a maneira como a similaridade é calculada e o número de termos da consulta podem levar a tempos de execução proibitivos se o processamento não for distribuído. Assim, esse artigo explora a possibilidade de uso do Hadoop Map-Reduce como forma de distribuir o processamento envolvido nesse tipo de busca. Além de propor um algoritmo de mapeamento, o artigo discute experimentos de busca realizados sobre um repositório digital de objetos. Os resultados mostram os cenários de teste em que o processamento distribuído se sobressai em relação ao processamento centralizado

    Anomalous lattice expansion of RuSr2Eu1.5Ce0.5Cu2O10(Ru-1222) magneto superconductor: A low temperature X-ray diffraction study

    Full text link
    This is the first report of the observation of the onset of excess volume and also of the strain along the a-axis near the magnetic ordering temperature in Ru-1222 superconductor, and indicates a coupling between the lattice and the magnetism in this system. Magnetization, magneto transport and thermoelectric power measurements being carried out on the same sample are also reported.Comment: 15 Pages Text Plus Figs. Physica C (2006) accepte

    Peptidases Are Potential Targets of Copper(II)-1,10-Phenanthroline-5,6-dione Complex, a Promising and Potent New Drug against Trichomonas Vaginalis

    Get PDF
    Trichomonas vaginalis is responsible for 156 million new cases per year worldwide. When present asymptomatically, the parasite can lead to serious complications, such as development of cervical and prostate cancer. As infection increases the acquisition and transmission of HIV, the control of trichomoniasis represents an important niche for the discovery and development of new antiparasitic molecules. This urogenital parasite synthesizes several molecules that allow the establishment and pathogenesis of infection. Among them, peptidases occupy key roles as virulence factors, and the inhibition of these enzymes has become an important mechanism for modulating pathogenesis. Based on these premises, our group recently reported the potent anti-T. vaginalis action of the metal-based complex [Cu(phendione)3](ClO4)2.4H2O (Cu-phendione). In the present study, we evaluated the influence of Cu-phendione on the modulation of proteolytic activities produced by T. vaginalis by biochemical and molecular approaches. Cu-phendione showed strong inhibitory potential against T. vaginalis peptidases, especially cysteine- and metallo-type peptidases. The latter revealed a more prominent effect at both the post-transcriptional and post-translational levels. Molecular Docking analysis confirmed the interaction of Cu-phendione, with high binding energy (9.7 and 10.7 kcalmol1, respectively) at the active site of both TvMP50 and TvGP63 metallopeptidases. In addition, Cu-phendione significantly reduced trophozoite-mediated cytolysis in human vaginal (HMVII) and monkey kidney (VERO) epithelial cell lineages. These results highlight the antiparasitic potential of Cu-phendione by interaction with important T. vaginalis virulence factors

    Quasinormal modes of Schwarzschild black holes in four and higher dimensions

    Full text link
    We make a thorough investigation of the asymptotic quasinormal modes of the four and five-dimensional Schwarzschild black hole for scalar, electromagnetic and gravitational perturbations. Our numerical results give full support to all the analytical predictions by Motl and Neitzke, for the leading term. We also compute the first order corrections analytically, by extending to higher dimensions, previous work of Musiri and Siopsis, and find excellent agreement with the numerical results. For generic spacetime dimension number D the first-order corrections go as 1n(D3)/(D2)\frac{1}{n^{(D-3)/(D-2)}}. This means that there is a more rapid convergence to the asymptotic value for the five dimensional case than for the four dimensional case, as we also show numerically.Comment: 12 pages, 5 figures, RevTeX4. v2. Typos corrected, references adde

    Highly Damped Quasinormal Modes of Kerr Black Holes: A Complete Numerical Investigation

    Full text link
    We compute for the first time very highly damped quasinormal modes of the (rotating) Kerr black hole. Our numerical technique is based on a decoupling of the radial and angular equations, performed using a large-frequency expansion for the angular separation constant_{s}A_{l m}. This allows us to go much further in overtone number than ever before. We find that the real part of the quasinormal frequencies approaches a non-zero constant value which does not depend on the spin s of the perturbing field and on the angular index l: \omega_R=m\varpi(a). We numerically compute \varpi(a). Leading-order corrections to the asymptotic frequency are likely to be of order 1/\omega_I. The imaginary part grows without bound, the spacing between consecutive modes being a monotonic function of a.Comment: 5 pages, 3 figure

    Nucleotides, β-glucans, ascorbic acid, α-tocoferol, and different concentrations of a vitamin-mineral premix promote growth of Nile tilapia juveniles

    Get PDF
    ABSTRACT Feed additives, such as β-glucans, nucleotides, ascorbic acid (vitamin C), and α-tocopherol (vitamin E) can improve fish immunity and contribute to enhanced zootechnical performance of the fish. This study aimed to evaluate the effect of different concentrations of vitamin- mineral premix with or without the inclusion of an immunostimulant boost (β-glucans, nucleotides and vitamins C and E) on the zootechnical performance, hemato-immunological parameters, histological changes, and survival of Nile tilapia juveniles. To this end, isocaloric and isoproteic diets were prepared with three different concentrations of vitamin-mineral premix (1.0, 1.5, and 2.0 kg ton-1); additionally, the effects of 4% immunostimulant boost in the diet were examined considering six diets (without the immunostimulant boost: 0.1%, 0.15%, and 0.2%, and with the immunostimulant boost: 0.1% I, 0.15% I, and 0.2% I). We used 24 experimental units, each including 15 fish. Nile tilapia juveniles (1.88 g±0.25) were fed for 50 d with supplemented diets. Further, zootechnical indexes; histological changes in the liver, spleen, and intestine; intestinal morphology; and hemato-immunological parameters were evaluated. The fish that received supplementation showed higher zootechnical values, compared to those that did not receive the supplementation of immunostimulant reinforcement. Weight gain (30.45g±3.06), daily weight gain (0.60g±0.06), final weight (32.41g±3.15) and feed conversion (0.95±0.06) were higher in tilapia fed with an inclusion concentration of 0.2%. Hematological parameters were not affected by either the pre-mix concentrations or the booster of the immunostimulant. There was an increase in the number of intestinal folds, length of the fold, total area and number of goblet cells in the group supplemented with immunostimulant reinforcement. Supplementation with the immunostimulant promoted growth and improved intestinal morphology and immunological parameters of Nile tilapia juveniles
    corecore