40 research outputs found
Circulating microRNA changes in patients with impaired glucose regulation
© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. We analysed if levels of four miRNAs would change after a lifestyle intervention involving dietary and exercises in prediabetes. MiRNAs previously shown to be associated with diabetes (Let-7a, Let-7e, miR-144 and miR-92a) were extracted from serum pre- and post-intervention. mRNA was extracted from fat-tissue for gene expression analyses. The intervention resulted in increased Let-7a and miR-92a. We found correlations between miRNAs and clinical variables (triglycerides, cholesterol, insulin, weight and BMI). We also found correlations between miRNAs and target genes, revealing a link between miR-92a and IGF system. A lifestyle intervention resulted in marked changes in miRNAs. The association of miRNAs with insulin and the IGF system (both receptors and binding proteins) may represent a mechanism of regulating IGFs metabolic actions
Phase diagram of the one-dimensional extended attractive Hubbard model for large nearest-neighbor repulsion
We consider the extended Hubbard model with attractive on-site interaction U
and nearest-neighbor repulsions V. We construct an effective Hamiltonian
H_{eff} for hopping t<<V and arbitrary U<0. Retaining the most important terms,
H_{eff} can be mapped onto two XXZ models, solved by the Bethe ansatz. The
quantum phase diagram shows two Luttinger liquid phases and a region of phase
separation between them. For density n<0.422 and U<-4, singlet superconducting
correlations dominate at large distances. For some parameters, the results are
in qualitative agreement with experiments in BaKBiO.Comment: 6 pages, 3 figures, submitted to Phys. Rev.
X-ray standing wave and reflectometric characterization of multilayer structures
Microstructural characterization of synthetic periodic multilayers by x-ray
standing waves have been presented. It has been shown that the analysis of
multilayers by combined x-ray reflectometry (XRR) and x-ray standing wave (XSW)
techniques can overcome the deficiencies of the individual techniques in
microstructural analysis. While interface roughnesses are more accurately
determined by the XRR technique, layer composition is more accurately
determined by the XSW technique where an element is directly identified by its
characteristic emission. These aspects have been explained with an example of a
20 period Pt/C multilayer. The composition of the C-layers due to Pt
dissolution in the C-layers, PtC, has been determined by the XSW
technique. In the XSW analysis when the whole amount of Pt present in the
C-layers is assumed to be within the broadened interface, it l eads to larger
interface roughness values, inconsistent with those determined by the XRR
technique. Constraining the interface roughness values to those determined by
the XRR technique, requires an additional amount of dissolved Pt in the
C-layers to expl ain the Pt fluorescence yield excited by the standing wave
field. This analysis provides the average composition PtC of the
C-layers .Comment: 12 pages RevTex, 10 eps figures embedde
Low-frequency Faraday rotation measures towards pulsars using LOFAR: probing the 3D Galactic halo magnetic field
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Maritime aerosol network as a component of AERONET - First results and comparison with global aerosol models and satellite retrievals
The Maritime Aerosol Network (MAN) has been collecting data over the oceans since November 2006. Over 80 cruises were completed through early 2010 with deployments continuing. Measurement areas included various parts of the Atlantic Ocean, the Northern and Southern Pacific Ocean, the South Indian Ocean, the Southern Ocean, the Arctic Ocean and inland seas. MAN deploys Microtops hand-held sunphotometers and utilizes a calibration procedure and data processing traceable to AERONET. Data collection included areas that previously had no aerosol optical depth (AOD) coverage at all, particularly vast areas of the Southern Ocean. The MAN data archive provides a valuable resource for aerosol studies in maritime environments. In the current paper we present results of AOD measurements over the oceans, and make a comparison with satellite AOD retrievals and model simulations