314 research outputs found

    On the most compact regular lattice in large dimensions: A statistical mechanical approach

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    In this paper I will approach the computation of the maximum density of regular lattices in large dimensions using a statistical mechanics approach. The starting point will be some theorems of Roger, which are virtually unknown in the community of physicists. Using his approach one can see that there are many similarities (and differences) with the problem of computing the entropy of a liquid of perfect spheres. The relation between the two problems is investigated in details. Some conjectures are presented, that need further investigation in order to check their consistency.Comment: 27 page

    Guidance for Restarting Inflammatory Bowel Disease Therapy in Patients Who Withheld Immunosuppressant Medications During COVID-19

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    Patients with inflammatory bowel diseases [IBD] are frequently treated with immunosuppressant medications. During the coronavirus disease 2019 [COVID-19] pandemic, recommendations for IBD management have included that patients should stay on their immunosuppressant medications if they are not infected with the severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2], but to temporarily hold these medications if symptomatic with COVID-19 or asymptomatic but have tested positive for SARS-CoV-2. As more IBD patients are infected globally, it is important to also understand how to manage IBD medications during convalescence while an individual with IBD is recovering from COVID-19. In this review, we address the differences between a test-based versus a symptoms-based strategy as related to COVID-19, and offer recommendations on when it is appropriate to consider restarting IBD therapy in patients testing positive for SARS-CoV-2 or with clinical symptoms consistent with COVID-19. In general, we recommend a symptoms-based approach, due to the current lack of confidence in the accuracy of available testing and the clinical significance of prolonged detection of virus via molecular testing

    Top-Down Approach to Unified Supergravity Models

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    We introduce a new approach for studying unified supergravity models. In this approach all the parameters of the grand unified theory (GUT) are fixed by imposing the corresponding number of low energy observables. This determines the remaining particle spectrum whose dependence on the low energy observables can now be investigated. We also include some SUSY threshold corrections that have previously been neglected. In particular the SUSY threshold corrections to the fermion masses can have a significant impact on the Yukawa coupling unification.Comment: 19 pages, uuencoded compressed ps file, DESY 94-057 (paper format corrected
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