PHP152 How are topics selected and prioritized by the national institute of health and care excellence (nice) and what might be the options if a technology is not selected?

Contents: Safety culture assessment saves Barilla money via better understanding of employee attitudes; Iowa State and CIRAS launch new online safety training modules; CIRAS sets table for food companies\u27 success; CIRAS helps Regency Consulting rocket share of federal contracts upward 28 percent; Iowa\u27s worker shortage: An old problem requiring new solutions; Filling the pipeline: By growing your own workers; Luring labor via LEGOS; Timerbline\u27s long-term relationship with CIRAS enhances company growth an dprofitability; CIRAS-arragned webinar to show job shops how to get more done factor; Want to buy a rapid prototyping machine? Don\u27t decide too rapidlyhttps://lib.dr.iastate.edu/ciras_news/1048/thumbnail.jp

Does maximising ball speed in cricket fast bowling necessitate higher ground reaction forces?

This is an Accepted Manuscript of an article published by Taylor & Francis in Journal of Sports Sciences on 17th July 2015, available online: http://www.tandfonline.com/10.1080/02640414.2015.1069375.This study aimed to investigate whether high peak ground reaction forces and high average loading rates are necessary to bowl fast. Kinematic and kinetic bowling data were collected for 20 elite male fast bowlers. A moderate non-significant correlation was found between ball speed and peak vertical ground reaction force with faster bowlers tending to have lower peak vertical ground reaction force (r = −0.364, P = 0.114). Faster ball speeds were correlated with both lower average vertical and lower average horizontal loading rates (r = −0.452, P = 0.046 and r = −0.484, P = 0.031, respectively). A larger horizontal (braking) impulse was associated with a faster ball speed (r = 0.574, P = 0.008) and a larger plant angle of the front leg (measured from the vertical) at front foot contact was associated with a larger horizontal impulse (r = 0.706, P = 0.001). These findings suggest that there does not necessarily need to be a trade-off between maximum ball release speed and the forces exerted on fast bowlers (peak ground reaction forces and average loading rates). Furthermore, it appears that one of the key determinants of ball speed is the horizontal impulse generated at the ground over the period from front foot contact until ball release

Supplementary Material for: Plasmin(ogen) Acquisition by Group A <b><i>Streptococcus</i></b> Protects against C3b-Mediated Neutrophil Killing

The globally significant human pathogen group A <i>Streptococcus</i> (GAS) sequesters the host protease plasmin to the cell surface during invasive disease initiation. Recent evidence has shown that localized plasmin activity prevents opsonization of several bacterial species by key components of the innate immune system in vitro. Here we demonstrate that plasmin at the GAS cell surface resulted in degradation of complement factor C3b, and that plasminogen acquisition is associated with a decrease in C3b opsonization and neutrophil-mediated killing in vitro. Furthermore, the ability to acquire cell surface plasmin(ogen) correlates directly with a decrease in C3b opsonization, neutrophil phagocytosis, and increased bacterial survival in a humanized plasminogen mouse model of infection. These findings demonstrate that localized plasmin(ogen) plays an important role in facilitating GAS escape from the host innate immune response and increases bacterial virulence in the early stages of infection