8 research outputs found

    Aquaculture diversification in South America: general views and facts and case studies of the Republic of Chile and the Federative Republic of Brazil.

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    Aquaculture and aquaculture diversification in South America: Facts and figures. Diversification of aquaculture in South America: a few figures and concepts. Aquaculture and aquaculture diversification in the Republic of Chile: Current situation, production models and strategies. The aquaculture diversification process in the Republic of Chile: recent history and current status. Diversification and the role of government and private industry. Technology and expertise, markets, institutional facilities and governance as drivers and/or constraints to aquaculture diversification in the Republic of Chile. The future of aquaculture diversification in the Republic of Chile. Aquaculture and aquaculture diversification in the Federative Republic of Brazil: Current situation and main species farmed. Recent history and current status of aquaculture diversification: Main drivers, constraints and species. The role of government, private industry and international organizations in aquaculture diversification. Technology and expertise, markets and institutional facilities as drivers and constraints. The future of aquaculture diversification: Main concerns, opportunities, restrictions, main species to consider.bitstream/item/164749/1/CNPASA-2017-fao.pd

    B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcγRIIb, which are modulated by anti-tumor necrosis factor therapy

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    Introduction: Several molecules help preserve peripheral B cell tolerance, but when altered, they may predispose to autoimmunity. This work studied the expression of the costimulatory molecule CD86 and the inhibitory receptor for IgG immune complexes FcγRIIb (CD32b), on B cells from rheumatoid arthritis (RA) patients, and the influence of anti-tumor necrosis factor (TNF) therapy.Methods: Peripheral B cells from 18 RA patients and 13 healthy donors were characterized using flow cytometry. Eleven patients who underwent a six-month adalimumab therapy were further assessed for phenotypic changes on their B cells.Results: RA patients exhibited a high percentage of naïve and memory B cells expressing CD86. In contrast, expression of FcγRIIb was significantly reduced on RA memory B cells and plasmablasts as compared to healthy donors, probably due to downregulation of this receptor when differentiating from naïve to memory cells. These alterations on FcγRIIb were associated with high levels

    Illness experiences in women with oral dryness as a result of Sjögrens’s syndrome: The patient point of view

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    Background Sjögren's syndrome and the associated dryness can have multiple consequences. The aim of the present qualitative study was to give an in-depth account of the life experiences of women with primary Sjögren's syndrome (pSS) and health-related behaviours, and to summarize these experiences in an integrated model. Methods Twelve women diagnosed with pSS who regularly attended the Hospital of the University of Chile participated in detailed interviews. The data were analysed using qualitative methods based on the principles of grounded theory. Results Selective coding identified three categories: illness experience, social interaction and psychological response. An integrated model was developed connecting these dynamic aspects and suggesting how they could lead to a life cycle crisis in cases of maladjustment. We found that problem-solving strategies, reconstruction of identity, acceptance and a social support may prevent this life cycle crisis. Discussion Xerostomia and other consequences of pSS can have a profound influence on daily life. However, the severity of the consequences depends on individual experiences with the illness, social influences and the psychological responses of the patient. Physicians, dentists and other healthcare professionals can help the patient by listening to their problems and exploring solutions based on a psychological approach
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