Observational constraints on dark matter-dark energy scattering cross section

In this letter, we report precise and robust observational constraints on dark matter-dark energy scattering cross section, using the latest data from cosmic microwave background (CMB) Planck temperature and polarization, baryon acoustic oscillations (BAO) measurements and weak gravitational lensing data from Canada-France-Hawaii Telescope Lensing Survey (CFHTLenS). The scattering scenario consists of a pure momentum exchange between the dark components, and we find $\sigma_d < 10^{-29} \, {\rm cm^2}$ at 95\% CL from the joint analysis (CMB + BAO + CFHTLenS), for typical dark matter particle mass of the order 1-10 ${\rm GeV}/c^2$. We notice that the scattering among the dark components may influence the growth of large scale structure in the Universe, leaving the background cosmology unaltered.Comment: 6 pages, 4 figures, 1 table, Minor changes/additions, Matches the version published in EPJ

Targeting crosstalk between Nrf-2, NF-κB and androgen receptor signaling in prostate cancer

Oxidative stress, inflammation and androgen receptor (AR) signaling play a pivotal role in the initiation, development and progression of prostate cancer (PCa). Numerous papers in the literature have documented the interconnection between oxidative stress and inflammation; and how antioxidants can combat the inflammation. It has been shown in the literature that both oxidative stress and inflammation regulate AR, the key receptor involved in the transition of PCa to castration resistant prostate cancer (CRPC). In this review, we discuss about the importance of targeting Nrf-2-antioxidant signaling, NF-&kappa;B inflammatory response and AR signaling in PCa. Finally, we discuss about the crosstalk between these three critical pathways as well as how the anti-inflammatory antioxidant phytochemicals like sulforaphane (SFN) and curcumin (CUR), which can also target AR, can be ideal candidates in the chemoprevention of PCa

Entropy spectrum of (1+1) dimensional stringy black holes

We explore the entropy spectrum of $(1+1)$ dimensional dilatonic stringy black holes via the adiabatic invariant integral method and the Bohr-Sommerfeld quantization rule. It is found that the corresponding spectrum depends on black hole parameters like charge, ADM mass and more interestingly on the dilatonic field. We calculate the entropy of the present black hole system via the Euclidean treatment of quantum gravity and study the thermodynamics of the black hole and find that the system does not undergo any phase transition.Comment: 10 pages, 2 figure

Phase error statistics of a phase-locked loop synchronized direct detection optical PPM communication system

Receiver timing synchronization of an optical Pulse-Position Modulation (PPM) communication system can be achieved using a phased-locked loop (PLL), provided the photodetector output is suitably processed. The magnitude of the PLL phase error is a good indicator of the timing error at the receiver decoder. The statistics of the phase error are investigated while varying several key system parameters such as PPM order, signal and background strengths, and PPL bandwidth. A practical optical communication system utilizing a laser diode transmitter and an avalanche photodiode in the receiver is described, and the sampled phase error data are presented. A linear regression analysis is applied to the data to obtain estimates of the relational constants involving the phase error variance and incident signal power