Dose-dependent new bone formation by extracorporeal shock wave application on the intact femur of rabbits

Background: Whereas various molecular working mechanisms of shock waves have been demonstrated, no study has assessed in detail the influence of varying energy flux densities (EFD) on new bone formation in vivo. Methods: Thirty Chinchilla bastard rabbits were randomly assigned to 5 groups (EFD 0.0, 0.35, 0.5, 0.9 and 1.2 mJ/mm(2)) and treated with extracorporeal shock waves at the distal femoral region (1,500 pulses; 1 Hz frequency). To investigate new bone formation, animals were injected with oxytetracycline at days 5-9 after shock wave application and sacrificed on day 10. Histological sections of all animals were examined using broad-band epifluorescent illumination, contact microradiography and Giemsa-Eosin staining. Results: Application of shock waves induced new bone formation beginning with 0.5 mJ/mm(2) EFD and increasing with 0.9 mJ/mm(2) and 1.2 mJ/mm(2). The latter EFD resulted in new bone formation also on the dorsal cortical bone; cortical fractures and periosteal detachment also occurred. Conclusion: Here, for the first time, a threshold level is presented for new bone formation after applying shock waves to intact bone in vivo. The findings of this study are of considerable significance for preventing unwanted side effects in new approaches in the clinical application of shock waves. Copyright (c) 2008 S. Karger AG, Basel

Recent Type II Radio Supernovae

We present the results of radio observations, taken primarily with the Very Large Array, of Supernovae 1993J, 2001gd, 2001em, 2002hh, 2004dj, and 2004et. We have fit a parameterized model to the multi-frequency observations of each supernova. We compare the observed and derived radio properties of these supernovae by optical classification and discuss the implications.Comment: 5 pages, 2 figures, 1 table Conference Proceedings: "Supernova 1987A: 20 Years After: Supernovae and Gamma-Ray Bursters" AIP, New York, eds. S. Immler, K.W. Weiler, and R. McCra

Phonon-Assisted Incoherent Excitation of a Quantum Dot and its Emission Properties

We present a detailed study of a phonon-assisted incoherent excitation mechanism of single quantum dots. A spectrally-detuned laser couples to a quantum dot transition by mediation of acoustic phonons, whereby excitation efficiencies up to 20 % with respect to strictly resonant excitation can be achieved at T = 9 K. Laser frequency-dependent analysis of the quantum dot intensity distinctly maps the underlying acoustic phonon bath and shows good agreement with our polaron master equation theory. An analytical solution for the photoluminescence is introduced which predicts a broadband incoherent coupling process when electron-phonon scattering is in the strong phonon coupling (polaronic) regime. Additionally, we investigate the coherence properties of the emitted light and study the impact of the relevant pump and phonon bath parameters

Acoustically driven ferromagnetic resonance

Surface acoustic waves (SAW) in the GHz frequency range are exploited for the all-elastic excitation and detection of ferromagnetic resonance (FMR) in a ferromagnetic/ferroelectric (nickel/lithium niobate) hybrid device. We measure the SAW magneto-transmission at room temperature as a function of frequency, external magnetic field magnitude, and orientation. Our data are well described by a modified Landau-Lifshitz-Gilbert approach, in which a virtual, strain-induced tickle field drives the magnetization precession. This causes a distinct magnetic field orientation dependence of elastically driven FMR that we observe in both model and experiment.Comment: 4 page

LHC Cleaning Efficiency with Imperfections

The performance reach of the LHC depends on the magnitude of beam losses and the achievable cleaning efficiency of its collimation system. The ideal performance reach for the nominal Phase 1 collimation system is reviewed. However, unavoidable imperfections affect any accelerator and can further deteriorate the collimation performance. Multiple static machine and collimator imperfections were included in the LHC tracking simulations. Error models for collimator jaw flatness, collimator setup accuracy, the LHC orbit and the LHC aperture were set up, based to the maximum extent possible on measurements and results of experimental beam tests. It is shown that combined “realistic” imperfections can reduce the LHC cleaning efficiency by about a factor 11 on average

Beam Commissioning Plan For LHC Collimation

The Large Hadron Collider extends the present state-of-the-art in stored beam energy by 2-3 orders of magnitude. A sophisticated system of collimators is implemented along the 27 km ring and mainly in two dedicated cleaning insertions, to intercept and absorb unavoidable beam losses which could induce quenches in the superconducting (sc) magnets. 88 collimators for the two beams are initially installed for the so called Phase 1. An optimized strategy for the commissioning of this considerable number of collimators has been defined. This optimized strategy maximizes cleaning efficiency and tolerances available for operation, while minimizing the required beam time for collimator setup and ensuring at all times the required passive machine protection. It is shown that operational tolerances from collimation can initially be significantly relaxed

Enterprise Responsibility for Personal Injury: Further Reflections

This Article, written by three contributors to the Reporters\u27 Study on Enterprise Responsibility for Personal Injury, offers further reflections about specific areas and proposals in the Study that have evoked important questions and comments. It addresses the concern that there are too many lawyers and lawsuits in the United States, and that it is this overpopulation of lawyers that is causing excessive tort litigation. It also addresses high damage awards and insurance premiums, it recommends refining products liability, and recommends organizational responsibility for medical malpractice. This Article is a supplement to the Study, and offers further examination of important issues raised in the Study