Assessment of Use and Utilisation of Library Resources, Services and Facilities by Law Students at Kristu Jayanti College of Law, Bangalore

The main aim of this study is to investigate the use of library resources, services and facilities by law students; it is mainly focused on use, purpose and satisfaction level with the library collection, services and facilities. This study used survey method to collect data. A well-structured questionnaire was distributed. Out of 110, only 91(83%) questionnaires were collected and select for analysis. Result revelled that library services and collection were satisfied further findings show users are not aware about Journals and E-Resources. So, study recommends that should conduct information literacy programme to promote awareness use of library services and use of resource

Investigational synthetic neuroactive steroid zuranolone in treatment of major depressive disorder with peripartum onset

Major depressive disorder with peripartum onset or peripartum depression is a common condition experienced by a large proportion of women and to some extent even in men. The current treatment strategies involve the use of conventional pharmacotherapeutic classes of drugs like selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and psychotherapy methods in the management of this condition. In this article, we try to review and evaluate the pathophysiology of the condition along with the safety and efficacy of the novel investigational therapeutic drug zuranolone, which is a synthetic neuroactive steroid (NAS) that has shown promise in clinical trials for the management of conditions like major depressive disorder, peripartum depression and bipolar disorder. The synthetic NAS zuranolone is an orally bioavailable positive allosteric modulator of the gamma amino butyric acid (GABAA) receptor, which can regulate the action of the GABAergic pathway implicated in many depressive episodes and also affect the normal functioning of the hypothalmo pituitary-adrenal (HPA) axis which is the core pathophysiological cause behind major depressive disorder with peripartum onset

Interaction of laser-cooled 87^{87}Rb atoms with higher order modes of an optical nanofiber

Optical nanofibres are used to confine light to subwavelength regions and are very promising tools for the development of optical fibre-based quantum networks using cold, neutral atoms. To date, experimental studies on atoms near nanofibres have focussed on fundamental fibre mode interactions. In this work, we demonstrate the integration of a few-mode optical nanofibre into a magneto-optical trap for $^{87}$Rb atoms. The nanofibre, with a waist diameter of $\sim$700 nm, supports both the fundamental and first group of higher order modes and is used for atomic fluorescence and absorption studies. In general, light propagating in higher order fibre modes has a greater evanescent field extension around the waist in comparison with the fundamental mode. By exploiting this behaviour, we demonstrate that the detected signal of fluorescent photons emitted from a cloud of cold atoms centred at the nanofibre waist is larger ($\sim$6 times) when higher order guided modes are considered as compared to the fundamental mode. Absorption of on-resonance, higher order mode probe light by the laser-cooled atoms is also observed. These advances should facilitate the realisation of atom trapping schemes based on higher order mode interference.Comment: 11 pages, 8 figure

Failure of evaporator tubes initiated by lamellar tearing during the commissioning of a waste heat recovery boiler

Successive failures of several new evaporator tubes during commissioning and trial run of a waste heat recovery boiler has been analyzed. The evaporator tubes are cold bent into U-shape and subsequently TIG welded to a 24-mm thick wear plate on either sides of the tube immediately adjacent to the bend. The failed samples showed stepped longitudinal cracks along the rolling direction and parallel to the weld fusion boundary at the fireside surface of the inner bend of the tube,prominently at the center of the bend. It was found that the failure of the evaporator tubes at the tube bends was initiated by lamellar tearing because of inherent defects in the material (segregation leading to banded structure), improper processing of material (inclusions with high aspect ratios along the rolling direction) and accelerated by high transverse shrinkage stresses over the entire bend portion of the tube introduced by the weld. The pre-existing fine cracks in the welded evaporator tube initiated by lamellar tearing have subsequently opened up during service when the total strain in the region increased because of steam pressure resulting in catastrophic failure of the tubes. Contrary to expectation, many of the elongated inclusions were found to be iron oxide scales and only few were manganese sulfide stringers enveloped by iron oxide scales. The iron oxide inclusions were resolved from the manganese sulfide by scanning electron microscopy and EDS spot analysis of the inclusions