837 research outputs found
Spectrum and Variability of Mrk501 as observed by the CAT Imaging Telescope
The CAT Imaging Telescope has observed the BL Lac object Markarian 501
between March and August 1997. We report here on the variability over this time
including several large flares. We present also preliminary spectra for all
these data, for the low emission state, and for the largest flare.Comment: 4 pages, 4 figures, Late
Observation of the Crab Nebula Gamma-Ray Emission Above 220 Gev by the Cat Cherenkov Imaging Telescope
The CAT imaging telescope, recently built on the site of the former solar
plant Themis (French Pyrenees), observed gamma-rays from the Crab nebula from
October 1996 to March 1997. This steady source, often considered as the
standard candle of very-high-energy gamma-ray astronomy, is used as a test-beam
to probe the performances of the new telescope, particularly its energy
threshold (220 GeV at 20 degrees zenith angle) and the stability of its
response. Due to the fine-grain camera, an accurate analysis of the
longitudinal profiles of shower images is performed, yielding the source
position in two dimensions for each individual shower.Comment: 5 pages, 3 figures, Tex, contribution to 25th ICRC Durba
Detection of Vhe Gamma-Rays from MRK 501 with the Cat Imaging Telescope
The CAT imaging telescope on the site on the former solar plant Themis has
been observing gamma-rays from Mrk501 above 220 GeV in March and April 1997.
This source is shown to be highly variable and the light curve is presented.
The detected gamma-ray rate for the most intense flare is in excess of 10 per
minute.Comment: 5 pages, 4 figures, Tex, contribution to 25th ICRC Durba
From the Feynman-Schwinger representation to the non-perturbative relativistic bound state interaction
We write the 4-point Green function in QCD in the Feynman-Schwinger
representation and show that all the dynamical information are contained in the
Wilson loop average. We work out the QED case in order to obtain the usual
Bethe-Salpeter kernel. Finally we discuss the QCD case in the non-perturbative
regime giving some insight in the nature of the interaction kernel.Comment: 25 pages, RevTex, 3 figures included, typos corrected, to appear in
Phys. Rev. D 5
The CAT Imaging Telescope for Very-High-Energy Gamma-Ray Astronomy
The CAT (Cherenkov Array at Themis) imaging telescope, equipped with a
very-high-definition camera (546 fast phototubes with 0.12 degrees spacing
surrounded by 54 larger tubes in two guard rings) started operation in Autumn
1996 on the site of the former solar plant Themis (France). Using the
atmospheric Cherenkov technique, it detects and identifies very high energy
gamma-rays in the range 250 GeV to a few tens of TeV. The instrument, which has
detected three sources (Crab nebula, Mrk 421 and Mrk 501), is described in
detail.Comment: 24 pages, 15 figures. submitted to Elsevier Preprin
CD8(+) T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo
Epstein Barr virus (EBV) is one of the most ubiquitous human pathogens in the world, persistently infecting more than 90% of the adult human population. It drives some of the strongest human CD8+ T cell responses, which can be observed during symptomatic primary
infection known as infectious mononucleosis (IM). Despite high viral loads and prolonged
CD8+ T cell stimulation during IM, EBV enters latency and is under lifelong immune control
in most individuals that experience this disease. We investigated whether changes in T cell
function, as frequently characterized by PD-1 up-regulation, occur during IM due to the prolonged exposure to high antigen levels. We readily detected the expansion of PD-1 positive
CD8+ T cells together with high frequencies of Tim-3, 2B4, and KLRG1 expression during
IM and in mice with reconstituted human immune system components (huNSG mice) that
had been infected with a high dose of EBV. These PD-1 positive CD8+ T cells, however,
retained proliferation, cytokine production, and cytotoxic abilities. Multiple subsets of CD8+
T cells expanded during EBV infection, including PD-1+
Tim-3+
KLRG1+ cells that express
CXCR5 and TCF-1 germinal center homing and memory markers, and may also contain
BATF3. Moreover, blocking the PD-1 axis compromised EBV specific immune control and
resulted in virus-associated lymphomagenesis. Finally, PD-1+
, Tim-3+
, and KLRG1+ CD8+ T
cell expansion coincided with declining viral loads during low dose EBV infection. These
findings suggest that EBV infection primes PD-1 positive CD8+ T cell populations that rely
on this receptor axis for the efficient immune control of this ubiquitous human tumor virus
A participatory physical and psychosocial intervention for balancing the demands and resources among industrial workers (PIPPI): study protocol of a cluster-randomized controlled trial
Background: Need for recovery and work ability are strongly associated with high employee turnover, well-being and sickness absence. However, scientific knowledge on effective interventions to improve work ability and decrease need for recovery is scarce. Thus, the present study aims to describe the background, design and protocol of a cluster randomized controlled trial evaluating the effectiveness of an intervention to reduce need for recovery and improve work ability among industrial workers. Methods/Design: A two-year cluster randomized controlled design will be utilized, in which controls will also receive the intervention in year two. More than 400 workers from three companies in Denmark will be aimed to be cluster randomized into intervention and control groups with at least 200 workers (at least 9 work teams) in each group. An organizational resources audit and subsequent action planning workshop will be carried out to map the existing resources and act upon initiatives not functioning as intended. Workshops will be conducted to train leaders and health and safety representatives in supporting and facilitating the intervention activities. Group and individual level participatory visual mapping sessions will be carried out allowing team members to discuss current physical and psychosocial work demands and resources, and develop action plans to minimize strain and if possible, optimize the resources. At all levels, the intervention will be integrated into the existing organization of work schedules. An extensive process and effect evaluation on need for recovery and work ability will be carried out via questionnaires, observations, interviews and organizational data assessed at several time points throughout the intervention period. Discussion: This study primarily aims to develop, implement and evaluate an intervention based on the abovementioned features which may improve the work environment, available resources and health of industrial workers, and hence their need for recovery and work ability
- …