Are genotypes of glutathione S-transferase superfamily a risk factor for childhood acute lymphoblastic leukemia? Results of an Italian case-control study.

Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer accounting for approximately 25\u201330% of all childhood malignancies. Despite much investigation, the causes of the disease are not yet fully understood. Like many other cancers, ALL is considered to be a complex disease determined by a combination of genetic and environmental factors