39 research outputs found

    Characterization of Three Carbon- and Nitrogen-Rich Particles from Comet 81P/WILD

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    Comets may sample the early solar system s complement of volatile-forming elements - including C and N - more fully and reliably than do the terrestrial planets or asteroids. Until recently, all elemental analyses of unambiguously cometary material were carried out remotely. The return of the Stardust mission makes it possible to analyze documented material from P81/Wild 2 in the laboratory Wild 2 particles fragmented when they stopped in the aerogel collectors. We have studied three fragments thought to be rich in C and N by using several techniques: FTIR to characterize organic matter; synchrotron-induced x-ray fluorescence (SXRF) to determine Fe and certain element/Fe ratios; SEM to image sample morphology and to detect semiquantitatively Mg, Al, Si, Ca, and Fe; and nuclear reaction analysis (NRA) to measure C, N, O, and Si

    Rariglanda jerseyensis a new ericalean fossil flower from the Late Cretaceous of New Jersey

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    A new species, Rariglanda jerseyensis, is described from well-preserved fusainized fossil flowers collected from the Late Cretaceous of New Jersey. Phylogenetic analyses and comparisons with extant and extinct taxa place R. jerseyensis within the monophyletic Ericales, sister to Clethraceae. The most distinctive feature of R. jerseyensis is a dense covering of conspicuous multicellular trichomes on the abaxial surface of the calyx. These multicellular trichomes appear to be glandular, and similar trichomes are found in several other, unrelated, Late Cretaceous fossils. In particular, the ericalean fossil Glandulocalyx upatoiensis bears the most similarity to R. jerseyensis, although differences in androecium and trichome characters clearly separate the two taxa. In addition, phylogenetic analyses confirm the position of G. upatoiensis within the Ericales, but place it within the sarracenioid clade, in a polytomy with Actinidiaceae and Roridulaceae. Past ecological studies associating trichomes with defense against herbivores and pathogens, coupled with the prevalence of multicellular trichomes on flowers among different lineages of fossils in the Cretaceous, suggest that glandular trichomes could have been an important adaptation against herbivore feeding during the Cretaceous.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author

    The diaphragms of fenestrated endothelia:gatekeepers of vascular permeability and blood composition

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    Fenestral and stomatal diaphragms are endothelial subcellular structures of unknown function that form on organelles implicated in vascular permeability: fenestrae, transendothelial channels, and caveolae. PV1 protein is required for diaphragm formation in vitro. Here, we report that deletion of the PV1-encoding Plvap gene in mice results in the absence of diaphragms and decreased survival. Loss of diaphragms did not affect the fenestrae and transendothelial channels formation but disrupted the barrier function of fenestrated capillaries, causing a major leak of plasma proteins. This disruption results in early death of animals due to severe noninflammatory protein-losing enteropathy. Deletion of PV1 in endothelium, but not in the hematopoietic compartment, recapitulates the phenotype of global PV1 deletion, whereas endothelial reconstitution of PV1 rescues the phenotype. Taken together, these data provide genetic evidence for the critical role of the diaphragms in fenestrated capillaries in the maintenance of blood composition
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