Understanding Superintendents’ Approaches to the Implementation of District Systems in the Context of a Crisis

The COVID-19 pandemic presented a crisis that district superintendents and their leadership teams had not before experienced. In a matter of weeks, school systems needed to transition away from a traditional learning model, where teaching and learning occurred in a physical classroom, to a virtual learning environment. School districts were provided little time to strategically develop a model to transform their systems to continue to meet student learning goals. The districts were still expected to fully operate, while prioritizing the acquisition of resources that could provide the means for a deliberate shift to establish a virtual learning system. This qualitative study examined how superintendents aligned resources and implemented systematic change during the initial months of COVID-19. Findings show that the voices of the local community stakeholders played the most integral part in identifying the values that primarily influenced how the districts navigated the crisis. Choice was the most prevalent value and, as a result, stakeholders were provided learning offerings in myriad formats. Superintendents considered how their decisions would affect each stakeholder group, as well as every aspect of their organizational structure

Substitution induced pinning in MgB_2 superconductor doped with SiC nano-particles

By doping MgB_2 superconductor with SiC nano-particles, we have successfully introduced pinning sites directly into the crystal lattice of MgB_2 grains (intra-grain pinning). It became possible due to the combination of counter-balanced Si and C co-substitution for B, leading to a large number of intra-granular dislocations and the dispersed nano-size impurities induced by the substitution. The magnetic field dependence of the critical current density was significantly improved in a wide temperature range, whereas the transition temperature in the sample MgB_2(SiC)_x having x = 0.34, the highest doping level prepared, dropped only by 2.6 K.Comment: 4 pages, 6 figure

Structure and expression of two nuclear receptor genes in marsupials: insights into the evolution of the antisense overlap between the α-thyroid hormone receptor and Rev-erbα

<p>Abstract</p> <p>Background</p> <p>Alternative processing of α-thyroid hormone receptor (TRα, NR1A1) mRNAs gives rise to two functionally antagonistic nuclear receptors: TRα1, the α-type receptor, and TRα2, a non-hormone binding variant that is found only in mammals. TRα2 shares an unusual antisense coding overlap with mRNA for Rev-erbα (NR1D1), another nuclear receptor protein. In this study we examine the structure and expression of these genes in the gray short-tailed opossum, <it>Monodelphis domestica</it>, in comparison with that of eutherian mammals and three other marsupial species, <it>Didelphis virginiana, Potorous tridactylus </it>and <it>Macropus eugenii</it>, in order to understand the evolution and regulatory role of this antisense overlap.</p> <p>Results</p> <p>The sequence, expression and genomic organization of mRNAs encoding TRα1 and Rev-erbα are very similar in the opossum and eutherian mammals. However, the sequence corresponding to the TRα2 coding region appears truncated by almost 100 amino acids. While expression of TRα1 and Rev-erbα was readily detected in all tissues of <it>M. domestica </it>ages 0 days to 18 weeks, TRα2 mRNA was not detected in any tissue or stage examined. These results contrast with the widespread and abundant expression of TRα2 in rodents and other eutherian mammals. To examine requirements for alternative splicing of TRα mRNAs, a series of chimeric minigenes was constructed. Results show that the opossum TRα2-specific 5' splice site sequence is fully competent for splicing but the sequence homologous to the TRα2 3' splice site is not, even though the marsupial sequences are remarkably similar to core splice site elements in rat.</p> <p>Conclusions</p> <p>Our results strongly suggest that the variant nuclear receptor isoform, TRα2, is not expressed in marsupials and that the antisense overlap between TRα and Rev-erbα thus is unique to eutherian mammals. Further investigation of the TRα and Rev-erbα genes in marsupial and eutherian species promises to yield additional insight into the physiological function of TRα2 and the role of the associated antisense overlap with Rev-erbα in regulating expression of these genes.</p

Doping Effect of Nano-Diamond on Superconductivity and Flux Pinning in MgB2

Doping effect of diamond nanoparticles on the superconducting properties of MgB2 bulk material has been studied. It is found that the superconducting transition temperature Tc of MgB2 is suppressed by the diamond-doping, however, the irreversibility field Hirr and the critical current density Jc are systematically enhanced. Microstructural analysis shows that the diamond-doped MgB2 superconductor consists of tightly-packed MgB2 nano-grains (~50-100 nm) with highly-dispersed and uniformly-distributed diamond nanoparticles (~10-20 nm) inside the grains. High density of dislocations and diamond nanoparticles may take the responsibility for the enhanced flux pinning in the diamond-doped MgB2.Comment: 16 pages, 6 figure

SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells

<p>Abstract</p> <p>Background</p> <p>The vertebrate pancreas contains islet, acinar and ductal cells. These cells derive from a transient pool of multipotent pancreatic progenitors during embryonic development. Insight into the genetic determinants regulating pancreatic organogenesis will help the development of cell-based therapies for the treatment of diabetes mellitus. <it>Suppressor enhancer lin12/Notch 1 like (Sel1l</it>) encodes a cytoplasmic protein that is highly expressed in the developing mouse pancreas. However, the morphological and molecular events regulated by <it>Sel1l </it>remain elusive.</p> <p>Results</p> <p>We have characterized the pancreatic phenotype of mice carrying a gene trap mutation in <it>Sel1l</it>. We show that <it>Sel1l </it>expression in the developing pancreas coincides with differentiation of the endocrine and exocrine lineages. Mice homozygous for the gene trap mutation die prenatally and display an impaired pancreatic epithelial morphology and cell differentiation. The pancreatic epithelial cells of <it>Sel1l </it>mutant embryos are confined to the progenitor cell state throughout the secondary transition. Pharmacological inhibition of Notch signaling partially rescues the pancreatic phenotype of <it>Sel1l </it>mutant embryos.</p> <p>Conclusions</p> <p>Together, these data suggest that <it>Sel1l </it>is essential for the growth and differentiation of endoderm-derived pancreatic epithelial cells during mouse embryonic development.</p

Characterisations of Classical and Non-classical states of Quantised Radiation

A new operator based condition for distinguishing classical from non-classical states of quantised radiation is developed. It exploits the fact that the normal ordering rule of correspondence to go from classical to quantum dynamical variables does not in general maintain positivity. It is shown that the approach naturally leads to distinguishing several layers of increasing nonclassicality, with more layers as the number of modes increases. A generalisation of the notion of subpoissonian statistics for two-mode radiation fields is achieved by analysing completely all correlations and fluctuations in quadratic combinations of mode annihilation and creation operators conserving the total photon number. This generalisation is nontrivial and intrinsically two-mode as it goes beyond all possible single mode projections of the two-mode field. The nonclassicality of pair coherent states, squeezed vacuum and squeezed thermal states is analysed and contrasted with one another, comparing the generalised subpoissonian statistics with extant signatures of nonclassical behaviour.Comment: 16 pages, Revtex, One postscript Figure compressed and uuencoded Replaced, minor changes in eq 4.30 and 4.32. no effect on the result

Heat flow in the Western Arctic Ocean (Amerasian Basin)

Author Posting. © American Geophysical Union, 2019. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research-Solid Earth 124(8), (2019): 7562-7587, doi: 10.1029/2019JB017587.From 1963 to 1973 the U.S. Geological Survey measured heat flow at 356 sites in the Amerasian Basin (Western Arctic Ocean) from a drifting ice island (T‐3). The resulting measurements, which are unevenly distributed on Alpha‐Mendeleev Ridge and in Canada and Nautilus Basins, greatly expand available heat flow data for the Arctic Ocean. Average T‐3 heat flow is ~54.7 ± 11.3 mW/m2, and Nautilus Basin is the only well‐surveyed area (~13% of data) with significantly higher average heat flow (63.8 mW/m2). Heat flow and bathymetry are not correlated at a large scale, and turbiditic surficial sediments (Canada and Nautilus Basins) have higher heat flow than the sediments that blanket the Alpha‐Mendeleev Ridge. Thermal gradients are mostly near‐linear, implying that conductive heat transport dominates and that near‐seafloor sediments are in thermal equilibrium with overlying bottom waters. Combining the heat flow data with modern seismic imagery suggests that some of the observed heat flow variability may be explained by local changes in lithology or the presence of basement faults that channel circulating seawater. A numerical model that incorporates thermal conductivity variations along a profile from Canada Basin (thick sediment on mostly oceanic crust) to Alpha Ridge (thin sediment over thick magmatic units associated with the High Arctic Large Igneous Province) predicts heat flow slightly lower than that observed on Alpha Ridge. This, along with other observations, implies that circulating fluids modulate conductive heat flow and contribute to high variability in the T‐3 data set.B.V. Marshall of the U.S. Geological Survey (USGS) was critical to the T‐3 heat flow studies and would have been included as a coauthor on this work if he were not deceased. The original T‐3 heat flow data acquisition program was supported by the USGS and by the Naval Arctic Research Laboratory of the Office of Naval Research. Over the decade of USGS research on T‐3 Ice Island, numerous researchers and technical staff, including B.V. Marshall, P. Twichell, D. Scoboria, J. Tailleur, B. Tailleur, and others, spent months on the island and endured difficult and sometimes dangerous conditions to acquire this data set alongside colleagues from other institutions. Outstanding support from the USGS Menlo Park office, transportation and logistics assistance from other U.S. federal government agencies, Arctic expertise supplied by native Alaskan communities, and collaboration with Lamont researchers made this research program possible. B. Lachenbruch and L. Lawver revived interest in this data set in 2016, and they, along with D. Darby and J. K. Hall, provided ancillary information on T‐3 studies. B. Clarke and M. Arsenault assisted with initial data digitization. We thank M. Jakobsson, R. Saltus, and G. Oakey for providing critical shapefiles and other data and R. Jackson and S. Mukasa for clarification on unpublished information. Reviews by J. Hopper, P. Hart, and W. Jokat improved the manuscript, and V. Atnipp Cross and A. Babb were instrumental in completion of data releases. The USGS's Coastal/Marine Hazards and Resources Program supported C.R. and D.H. between 2016 and 2019, and C.R. used office space provided by the Earth Resources Laboratory at the Massachusetts Institute of Technology during completion of this work. Data in Figure 11 were provided by the U.S. Extended Continental Shelf (ECS) Project. The opinions, findings, and conclusions stated herein are those of the authors and the U.S. Geological Survey, but do not necessarily reflect those of the U.S. ECS Project. Any use of trade, firm, or product name is for descriptive purposes only and does not imply endorsement by the U.S. Government. Digital data, metadata, and supporting plots for T‐3 heat flow, navigation, and radiogenic heat content, along with Lamont gravity and magnetics data, are available from Ruppel et al. (2019), and the original T‐3 expedition report with explanatory metadata can be downloaded from Lachenbruch et al. (2019)

LOW ENERGY SUPERSYMMETRY PHENOMENOLOGY

We summarize the current status and future prospects for low energy (weak scale) supersymmetry. In particular, we evaluate the capabilities of various $e^+e^-$, $p\bar p$ and $pp$ colliders to discover evidence for supersymmetric particles. Furthermore, assuming supersymmetry is discovered, we discuss capabilities of future facilities to dis-entangle the anticipated spectrum of super-particles, and, via precision measurements, to test mass and coupling parameters for comparison with various theoretical expectations. We comment upon the complementarity of proposed hadron and $e^+e^-$ machines for a comprehensive study of low energy supersymmetry.Comment: 74 page (Latex) file; a PS or uuencoded manuscript with embedded figures is available via anonymous ftp at ftp://hep.fsu.edu/preprints/baer/FSUHEP950401.ps or .uu . Contributed chapter to DPF study group on Electroweak Symmetry Breaking and Beyond the Standard Model