Nearshore cool-water carbonate sedimentation and provenance of Holocene calcareous strandline dunes, southeastern Australia

<p>The southeastern coastal plain of South Australia contains a spectacular and world-renowned suite of Quaternary calcareous eolianites. This study is focused on the provenance of components in the Holocene, actively forming sector, of these carbonate eolian deposits. Research was carried out along seven transects across a lateral distance of 120 km from ∼30 m water depth offshore across the beach and into the dunes. Offshore sediments were acquired via grab sampling and SCUBA. Results indicate that dunes of the southern Lacepede and Bonney coasts are composed of siliciclastic particles (mainly quartz), relict allochems, Cenozoic and limestone pieces, but dominated by Holocene invertebrate and calcareous algal biofragments. The most numerous grains are from molluscs > benthic foraminifera ≥ coralline algae, > echinoids and > bryozoans. Most of these particles originate in carbonate factories such as macroalgal forests, rocky reefs, seagrass meadows and low-relief sea-floor rockgrounds. Incorporation of Holocene carbonate skeletons into coastal dunes, however, depends on a combination of: (1) the addition of infauna from intertidal and nearshore environments; (2) the physical characteristics of different allochems and their ability to withstand bioerosion, fragmentation and abrasion; (3) the character of the wave and swell climate; and (4) the nature of eolian transport. Most eolian dune sediment is derived from nearshore and intertidal carbonate factories. This is well illustrated by the abundance of robust infaunal bivalves that inhabit the nearshore sands and virtual absence of bryozoans that are common as sediment particles in offshore water depths >15 m. Importantly, the calcareous eolianites in this cool-water, open-platform carbonate setting are not simply an allochthonous reflection of the offshore marine shelf factories, but more a product of autothonous shallow nearshore–intertidal skeletal production and modification. These findings explain the preponderance of mollusc fragments and lack of bryozoans in similar older Pleistocene calcareous eolianites up to <i>ca</i> 1 million years old across ∼2000 km of southern Australia with implications for the older rock record.</p

Quantum chemical insight into molecular structure, density functional theory calculations, vibrational dynamics, natural population analysis, Hirshfeld analysis, and molecular docking approach to chalcone 1-4-bromophenyl-3-(2-methoxyphenyl)prop-2-en-1-one

<p>The structure of the novel chalcone 1-4-bromophenyl-3-(2-methoxyphenyl)prop-2-en-1-one has been characterized by Fourier transform infrared and Fourier transform Raman. Density functional theory with Becke, 3-parameter, Lee-Yang-Parr functional was used for the optimization of geometry. The comprehensive assignments of the vibrational spectra have been performed with the aid of normal coordinate analysis. Stability of the molecule and intra/intermolecular charge transfer have been analyzed using natural bond orbital analysis. The existence of intermolecular C-H⋯O, blueshifted hydrogen bond was investigated by bond length variation. Hirshfeld and two-dimensional fingerprint plot analyses have been performed to study the nature of interactions present in the molecule. The docked complex gives a constancy of −8.2 kcal/mol toward the androgen receptor.</p

Additional file 1: of Urothelial cells may indicate underlying bacteriuria in pregnancy at term: a comparative study

Artemis questionnaire. Description: Detailed 49 item questionnaire divided into four categories: stress incontinence symptoms, overactive bladder symptoms, voiding symptoms, and pain symptoms used to create a lower urinary tract symptom (LUTS) profile as an assessment of bladder distress. (DOCX 145 kb

Additional file 5: Figure S2. of Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma

CSF DNA Yield Relative to Tumor Location. Greater DNA concentration (ng/μL) was extracted from lateral ventricular CSF from patients with interventricular tumors or tumors adjacent to the lateral ventricle, in comparison to patients with tumors in a distant or non-adjacent anatomic location (Adjacent mean = 1.00 ng DNA/μL CSF; Distant mean = 0.16 ng/μL CSF; Mann–Whitney U test, p = 0.39). Scatter plot whiskers: mean with standard deviation. (PDF 481 kb

Additional file 3: Figure S1. of Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma

Negative control for mutation-specific primers. CSF from a patient with congenital hydrocephalus and no history of brain tumor (PID 12) was analyzed using H3F3A c.83A > T mutation-specific primers to demonstrate primer specificity, with DNA from primary tumor cells (SF8628) as a positive control. (PDF 414 kb

Additional file 1: Table S1. of Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma

List of Histone H3 Primer Sequences. The sequences and properties of primers used in this study are described. Melting temperature (TM) was calculated at 0.4 ÎźM.fdg. (XLS 22 kb