The F-Landscape: Dynamically Determining the Multiverse

We evolve our Multiverse Blueprints to characterize our local neighborhood of the String Landscape and the Multiverse of plausible string, M- and F-theory vacua. Building upon the tripodal foundations of i) the Flipped SU(5) Grand Unified Theory (GUT), ii) extra TeV-Scale vector-like multiplets derived out of F-theory, and iii) the dynamics of No-Scale Supergravity, together dubbed No-Scale F-SU(5), we demonstrate the existence of a continuous family of solutions which might adeptly describe the dynamics of distinctive universes. This Multiverse landscape of F-SU(5) solutions, which we shall refer to as the F-Landscape, accommodates a subset of universes compatible with the presently known experimental uncertainties of our own universe. We show that by secondarily minimizing the minimum of the scalar Higgs potential of each solution within the F-Landscape, a continuous hypervolume of distinct minimum minimorum can be engineered which comprise a regional dominion of universes, with our own universe cast as the bellwether. We conjecture that an experimental signal at the LHC of the No-Scale F-SU(5) framework's applicability to our own universe might sensibly be extrapolated as corroborating evidence for the role of string, M- and F-theory as a master theory of the Multiverse, with No-Scale supergravity as a crucial and pervasive reinforcing structure.Comment: 15 Pages, 7 Figures, 1 Tabl

Freund-Rubin Revisited

We utilise the duality between M theory and Type IIA string theory to show the existence of Freund-Rubin compactifications of M theory on 7-manifolds with singularities supporting chiral fermions. This leads to a concrete way to study phenomenologically interesting quantum gravity vacua using a holographically dual three dimensional field theory.Comment: reference adde

Paracrinicity: The Story of 30 Years of Cellular Pituitary Crosstalk

Living organisms represent, in essence, dynamic interactions of high complexity between membrane-separated compartments that cannot exist on their own, but reach behaviour in co-ordination. In multicellular organisms, there must be communication and co-ordination between individual cells and cell groups to achieve appropriate behaviour of the system. Depending on the mode of signal transportation and the target, intercellular communication is neuronal, hormonal, paracrine or juxtacrine. Cell signalling can also be self-targeting or autocrine. Although the notion of paracrine and autocrine signalling was already suggested more than 100 years ago, it is only during the last 30 years that these mechanisms have been characterised. In the anterior pituitary, paracrine communication and autocrine loops that operate during fetal and postnatal development in mammals and lower vertebrates have been shown in all hormonal cell types and in folliculo-stellate cells. More than 100 compounds have been identified that have, or may have, paracrine or autocrine actions. They include the neurotransmitters acetylcholine and γ-aminobutyric acid, peptides such as vasoactive intestinal peptide, galanin, endothelins, calcitonin, neuromedin B and melanocortins, growth factors of the epidermal growth factor, fibroblast growth factor, nerve growth factor and transforming growth factor-β families, cytokines, tissue factors such as annexin-1 and follistatin, hormones, nitric oxide, purines, retinoids and fatty acid derivatives. In addition, connective tissue cells, endothelial cells and vascular pericytes may influence paracrinicity by delivering growth factors, cytokines, heparan sulphate proteoglycans and proteases. Basement membranes may influence paracrine signalling through the binding of signalling molecules to heparan sulphate proteoglycans. Paracrine/autocrine actions are highly context-dependent. They are turned on/off when hormonal outputs need to be adapted to changing demands of the organism, such as during reproduction, stress, inflammation, starvation and circadian rhythms. Specificity and selectivity in autocrine/paracrine interactions may rely on microanatomical specialisations, functional compartmentalisation in receptor–ligand distribution and the non-equilibrium dynamics of the receptor–ligand interactions in the loops

Runaway dilatonic domain walls

We explore the stability of domain wall and bubble solutions in theories with compact extra dimensions. The energy density stored inside of the wall can destabilize the volume modulus of a compactification, leading to solutions containing either a timelike singularity or a region where space decompactifies, depending on the metric ansatz. We determine the structure of such solutions both analytically and using numerical simulations, and analyze how they arise in compactifications of Einstein--Maxwell theory and Type IIB string theory. The existence of instabilities has important implications for the formation of networks of topological defects and the population of vacua during eternal inflation.Comment: 29 pages with 19 figures. Replaced to match published versio

Applications of an exact counting formula in the Bousso-Polchinski Landscape

The Bousso-Polchinski (BP) Landscape is a proposal for solving the Cosmological Constant Problem. The solution requires counting the states in a very thin shell in flux space. We find an exact formula for this counting problem which has two simple asymptotic regime one of them being the method of counting low $\Lambda$ states given originally by Bousso and Polchinski. We finally give some applications of the extended formula: a robust property of the Landscape which can be identified with an effective occupation number, an estimator for the minimum cosmological constant and a possible influence on the KKLT stabilization mechanism.Comment: 43 pages, 11 figures, 2 appendices. We have added a new section (3.4) on the influence of the fraction of non-vanishing fluxes in the KKLT mechanism. Other minor changes also mad

Microbiomes Reduce Their Host's Sensitivity to Interspecific Interactions.

Bacteria associated with eukaryotic hosts can affect host fitness and trophic interactions between eukaryotes, but the extent to which bacteria influence the eukaryotic species interactions within trophic levels that modulate biodiversity and species coexistence is mostly unknown. Here, we used phytoplankton, which are a classic model for evaluating interactions between species, grown with and without associated bacteria to test whether the bacteria alter the strength and type of species interactions within a trophic level. We demonstrate that host-associated bacteria alter host growth rates and carrying capacity. This did not change the type but frequently changed the strength of host interspecific interactions by facilitating host growth in the presence of an established species. These findings indicate that microbiomes can regulate their host species' interspecific interactions. As between-species interaction strength impacts their ability to coexist, our findings show that microbiomes have the potential to modulate eukaryotic species diversity and community composition.IMPORTANCE Description of the Earth's microbiota has recently undergone a phenomenal expansion that has challenged basic assumptions in many areas of biology, including hominid evolution, human gastrointestinal and neurodevelopmental disorders, and plant adaptation to climate change. By using the classic model system of freshwater phytoplankton that has been drawn upon for numerous foundational theories in ecology, we show that microbiomes, by facilitating their host population, can also influence between-species interactions among their eukaryotic hosts. Between-species interactions, including competition for resources, has been a central tenet in the field of ecology because of its implications for the diversity and composition of communities and how this in turn shapes ecosystem functioning

Exact solutions for supersymmetric stationary black hole composites

Four dimensional N=2 supergravity has regular, stationary, asymptotically flat BPS solutions with intrinsic angular momentum, describing bound states of separate extremal black holes with mutually nonlocal charges. Though the existence and some properties of these solutions were established some time ago, fully explicit analytic solutions were lacking thus far. In this note, we fill this gap. We show in general that explicit solutions can be constructed whenever an explicit formula is known in the theory at hand for the Bekenstein-Hawking entropy of a single black hole as a function of its charges, and illustrate this with some simple examples. We also give an example of moduli-dependent black hole entropy.Comment: 13 pages, 1 figur

Constructive Wall-Crossing and Seiberg-Witten

We outline a comprehensive and first-principle solution to the wall-crossing problem in D=4 N=2 Seiberg-Witten theories. We start with a brief review of the multi-centered nature of the typical BPS states and recall how the wall-crossing problem thus becomes really a bound state formation/dissociation problem. Low energy dynamics for arbitrary collections of dyons is derived, from Seiberg-Witten theory, with the proximity to the so-called marginal stability wall playing the role of the small expansion parameter. We find that, surprisingly, the $\mathbb{R}^{3n}$ low energy dynamics of n+1 BPS dyons cannot be consistently reduced to the classical moduli space, \CM, yet the index can be phrased in terms of \CM. We also explain how an equivariant version of this index computes the protected spin character of the underlying field theory, where SO(3)_\CJ isometry of \CM turns out to be the diagonal subgroup of $SU(2)_L$ spatial rotation and $SU(2)_R$ R-symmetry. The so-called rational invariants, previously seen in the Kontsevich-Soibelman formalism of wall-crossing, are shown to emerge naturally from the orbifolding projection due to Bose/Fermi statistics.Comment: 25 pages, conference proceeding contribution for "Progress of Quantum Field Theory and String Theory," Osaka, April 201

Bubbling solutions, entropy enhancement and the fuzzball proposal

In this short note we explain the main idea of the work done in arXiv:0804.4487[hep-th] and arXiv:0812.2942[hep-th]. We present a family of black hole microstates, the bubbling solutions. We then explain how supertubes placed in such backgrounds have their entropy enhanced by the presence of the background dipole charges. This indicates this could account for a large amount in the entropy of the three charge black hole.Comment: 2 pages, contribution to the Cargese 2008 proceedings: Theory and Particle Physics: the LHC perspective and beyon

Type IIB Flux Vacua from M-theory via F-theory

We study in detail some aspects of duality between type IIB and M-theory. We focus on the duality between type IIB string theory on K3 x T^2/Z_2 orientifold and M-theory on K3 x K3, in the F-theory limit. We give the explicit map between the fields and in particular between the moduli of compactification, studying their behavior under the F-theory limit. Turning on fluxes generates a potential for the moduli both in type IIB and in M-theory. We verify that the type IIB analysis gives the same results of the F-theory analysis. In particular, we check that the two potentials match.Comment: 24 pages; reference correcte