A CrC^{r} Closing Lemma for a Class of Symplectic Diffeomorphisms

We prove a $C^r$ closing lemma for a class of partially hyperbolic symplectic diffeomorphisms. We show that for a generic $C^r$ symplectic diffeomorphism, $r =1, 2, ...,$, with two dimensional center and close to a product map, the set of all periodic points is dense

Hole burning in a nanomechanical resonator coupled to a Cooper pair box

We propose a scheme to create holes in the statistical distribution of excitations of a nanomechanical resonator. It employs a controllable coupling between this system and a Cooper pair box. The success probability and the fidelity are calculated and compared with those obtained in the atom-field system via distinct schemes. As an application we show how to use the hole-burning scheme to prepare (low excited) Fock states.Comment: 7 pages, 10 figure

Quantum switch for single-photon transport in a coupled superconducting transmission line resonator array

We propose and study an approach to realize quantum switch for single-photon transport in a coupled superconducting transmission line resonator (TLR) array with one controllable hopping interaction. We find that the single-photon with arbitrary wavevector can transport in a controllable way in this system. We also study how to realize controllable hopping interaction between two TLRs via a superconducting quantum interference device (SQUID). When the frequency of the SQUID is largely detuned from those of the two TLRs, the variables of the SQUID can be adiabatically eliminated and thus a controllable interaction between two TLRs can be obtained.Comment: 4 pages,3 figure

Learning to Generate Images with Perceptual Similarity Metrics

Deep networks are increasingly being applied to problems involving image synthesis, e.g., generating images from textual descriptions and reconstructing an input image from a compact representation. Supervised training of image-synthesis networks typically uses a pixel-wise loss (PL) to indicate the mismatch between a generated image and its corresponding target image. We propose instead to use a loss function that is better calibrated to human perceptual judgments of image quality: the multiscale structural-similarity score (MS-SSIM). Because MS-SSIM is differentiable, it is easily incorporated into gradient-descent learning. We compare the consequences of using MS-SSIM versus PL loss on training deterministic and stochastic autoencoders. For three different architectures, we collected human judgments of the quality of image reconstructions. Observers reliably prefer images synthesized by MS-SSIM-optimized models over those synthesized by PL-optimized models, for two distinct PL measures ($\ell_1$ and $\ell_2$ distances). We also explore the effect of training objective on image encoding and analyze conditions under which perceptually-optimized representations yield better performance on image classification. Finally, we demonstrate the superiority of perceptually-optimized networks for super-resolution imaging. Just as computer vision has advanced through the use of convolutional architectures that mimic the structure of the mammalian visual system, we argue that significant additional advances can be made in modeling images through the use of training objectives that are well aligned to characteristics of human perception

World Market for Mergers and Acquisitions

Despite the fact that one-third of worldwide mergers involve firms from different countries, the vast majority of the academic literature on mergers studies domestic mergers. What little has been written about cross-border mergers has focused on public firms, usually from the United States. Yet, the vast majority of cross-border mergers involve private firms that are not from the United States. We provide an analysis of a sample of 56,978 cross-border mergers occurring between 1990 and 2007. We first characterize the patterns of who buys whom: Geography matters, with firms being much more likely to purchase firms in nearby countries than in countries far away. Purchasers are usually but not always from developed countries and they tend to purchase firms in countries with lower accounting standards. A significant factor in determining acquisition patterns is currency movements; firms tend to purchase firms from countries relative to which the currency of the acquirers country has appreciated. In addition, economy-wide factors reflected in the countrys stock market returns lead to acquisitions as well. Both the currency and stock market effect could suggest either misvaluation or wealth explanations. Our evidence is more consistent with the wealth explanation than the misvaluation explanation.Mergers; Currency movements; Market movements; Valuation

Augmenting the Calvin-Benson-Bassham cycle by a synthetic malyl-CoA-glycerate carbon fixation pathway.

The Calvin-Benson-Bassham (CBB) cycle is presumably evolved for optimal synthesis of C3 sugars, but not for the production of C2 metabolite acetyl-CoA. The carbon loss in producing acetyl-CoA from decarboxylation of C3 sugar limits the maximum carbon yield of photosynthesis. Here we design a synthetic malyl-CoA-glycerate (MCG) pathway to augment the CBB cycle for efficient acetyl-CoA synthesis. This pathway converts a C3 metabolite to two acetyl-CoA by fixation of one additional CO2 equivalent, or assimilates glyoxylate, a photorespiration intermediate, to produce acetyl-CoA without net carbon loss. We first functionally demonstrate the design of the MCG pathway in vitro and in Escherichia coli. We then implement the pathway in a photosynthetic organism Synechococcus elongates PCC7942, and show that it increases the intracellular acetyl-CoA pool and enhances bicarbonate assimilation by roughly 2-fold. This work provides a strategy to improve carbon fixation efficiency in photosynthetic organisms

High-frequency oscillatory ventilation in pediatric acute hypoxemic respiratory failure: disease-specific morbidity survival analysis.

BackgroundMultiple ventilatory strategies for acute hypoxemic respiratory failure (AHRF) in children have been advocated, including high-frequency oscillatory ventilation (HFOV). Despite the frequent deployment of HFOV, randomized controlled trials remain elusive and currently there are no pediatric trials looking at its use. Our longitudinal study analyzed the predictive clinical outcome of HFOV in pediatric AHRF given disease-specific morbidity.MethodsA retrospective 8-year review on pediatric intensive care unit admissions with AHRF ventilated by HFOV was performed. Primary outcomes included survival, morbidity, length of stay (LOS), and factors associated with survival or mortality.ResultsA total of 102 patients underwent HFOV with a 66 % overall survival rate. Survivors had a greater LOS than nonsurvivors (p = 0.001). Mortality odds ratio (OR) for patients without bronchiolitis was 8.19 (CI = 1.02, 65.43), and without pneumonia it was 3.07 (CI = 1.12, 8.39). A lower oxygenation index (OI) after HFOV commencement and at subsequent time points analyzed predicted survival. After 24 h, mortality was associated with an OI > 35 [OR = 31.11 (CI = 3.25, 297.98)]. Sepsis-related mortality was associated with a higher baseline FiO(2) (0.88 vs. 0.65), higher OI (42 vs. 22), and augmented metabolic acidosis (pH of 7.25 vs. 7.32) evaluated 4 h on HFOV (p < 0.05).ConclusionHigh-frequency oscillatory ventilation may be safely utilized. It has a 66 % overall survival rate in pediatric AHRF of various etiologies. Patients with morbidity limited to the respiratory system and optimized oxygenation indices are most likely to survive on HFOV

A Case for Redundant Arrays of Hybrid Disks (RAHD)

Hybrid Hard Disk Drive was originally concepted by Samsung, which incorporates a Flash memory in a magnetic disk. The combined ultra-high-density benefits of magnetic storage and the low-power and fast read access of NAND technology inspires us to construct Redundant Arrays of Hybrid Disks (RAHD) to offer a possible alternative to today’s Redundant Arrays of Independent Disks (RAIDs) and/or Massive Arrays of Idle Disks (MAIDs). We first design an internal management system (including Energy-Efficient Control) for hybrid disks. Three traces collected from real systems as well as a synthetic trace are then used to evaluate the RAHD arrays. The trace-driven experimental results show: in the high speed mode, a RAHD outplays the purely-magnetic-disk-based RAIDs by a factor of 2.4–4; in the energy-efficient mode, a RAHD4/5 can save up to 89% of energy at little performance degradationPeer reviewe

The relationship between the cranial base and jaw base in a Chinese population

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Provision of secondary frequency regulation by coordinated dispatch of industrial loads and thermal power plants

Demand responsive industrial loads with high thermal inertia have potential to provide ancillary service for frequency regulation in the power market. To capture the benefit, this study proposes a new hierarchical framework to coordinate the demand responsive industrial loads with thermal power plants in an industrial park for secondary frequency control. In the proposed framework, demand responsive loads and generating resources are coordinated for optimal dispatch in two-time scales: (1) the regulation reserve of the industrial park is optimally scheduled in a day-ahead manner. The stochastic regulation signal is replaced by the specific extremely trajectories. Furthermore, the extremely trajectories are achieved by the day-ahead predicted regulation mileage. The resulting benefit is to transform the stochastic reserve scheduling problem into a deterministic optimization; (2) a model predictive control strategy is proposed to dispatch the industry park in real time with an objective to maximize the revenue. The proposed technology is tested using a real-world industrial electrolysis power system based upon Pennsylvania, Jersey, and Maryland (PJM) power market. Various scenarios are simulated to study the performance of the proposed approach to enable industry parks to provide ancillary service into the power market. The simulation results indicate that an industrial park with a capacity of 500 MW can provide up to 40 MW ancillary service for participation in the secondary frequency regulation. The proposed strategy is demonstrated to be capable of maintaining the economic and secure operation of the industrial park while satisfying performance requirements from the real world regulation market