10,519 research outputs found
Coupled SDW and Superconducting Order in FFLO State of CeCoIn
The mechanism of incommensurate (IC) spin-density-wave (SDW) order observed
in the Flude-Ferrell-Larkin-Ovchinnikov (FFLO) phase of CeCoIn is discussed
on the basis of new mode-coupling scheme among IC-SDW order, two
superconducting orders of FFLO with B () symmetry
and -pairing of odd-parity. Unlike the mode-coupling schemes proposed by
Kenzelmann et al, Sciencexpress, 21 August (2008), that proposed in the present
Letter can offer a simple explanation for why the IC-SDW order is observed only
in FFLO phase and the IC wave vector is rather robust against the magnetic
field.Comment: 3pages, 1 figure, accepted for publication in J. Phys. Soc. Jpn.,
Vol.77 (2008), No.1
A Novel Lumbar Motion Segment Classification to Predict Changes in Segmental Sagittal Alignment After Lateral Interbody Fixation.
Study designRetrospective cohort study.ObjectivesLateral interbody fixation is being increasingly used for the correction of segmental sagittal parameters. One factor that affects postoperative correction is the resistance afforded by posterior hypertrophic facet joints in the degenerative lumbar spine. In this article, we describe a novel preoperative motion segment classification system to predict postoperative correction of segmental sagittal alignment after lateral lumbar interbody fusion.MethodsPreoperative computed tomography scans were analyzed for segmental facet osseous anatomy for all patients undergoing lateral lumbar interbody fusion at 3 institutions. Each facet was assigned a facet grade (min = 0, max = 2), and the sum of the bilateral facet grades was the final motion segment grade (MSG; min = 0, max = 4). Preoperative and postoperative segmental lordosis was measured on standing lateral radiographs. Postoperative segmental lordosis was also conveyed as a percentage of the implanted graft lordosis (%GL). Simple linear regression was conducted to predict the postoperative segmental %GL according to MSG.ResultsA total of 36 patients with 59 operated levels were identified. There were 19 levels with MSG 0, 14 levels with MSG 1, 13 levels with MSG 2, 8 levels with MSG 3, and 5 levels with MSG 4. Mean %GL was 115%, 90%, 77%, 43%, and 5% for MSG 0 to 4, respectively. MSG significantly predicted postoperative %GL (P < .01). Each increase in MSG was associated with a 28% decrease in %GL.ConclusionsWe propose a novel facet-based motion segment classification system that significantly predicted postoperative segmental lordosis after lateral lumbar interbody fusion
Feed Utilisation Efficiency of Lupin Inclusion in Cobia: Role of Dietary Organic Selenium Supplementation
The dietary selenium (Se) requirement has been determined for cobia Rachycentron canadum using purified diet; however, its role in the utilisation of plant-derived ingredients has not been evaluated in the species. Therefore, a 3 x 2 factorial experimental design involving three inclusion levels (0, 210 and 315 g/kg) of lupin Lupinus angustifolius kernel meal (LKM) and two concentrations (0 and 0.8 mg/kg) of Se was used to evaluate the effects of Se supplementation in conjunction with LKM on the growth, feed utilisation and physiological responses in the cobia. Six isonitrogenous (46.5 % crude protein) and isoenergetic (21 MJ/kg gross energy) diets were formulated and fed to cobia for 7 weeks in a flow-through seawater system. The results showed significant effects of Se supplementation and its interaction with dietary lupin on the growth and feed efficiency of cobia. Se supplementation significantly improved the growth and feed utilisation efficiency in cobia fed lupin-based diets. The nutrient digestibility of fish fed supplemental Se lupin-based diets was significantly higher than that of fish fed diets without Se supplementation at each inclusion level of LKM. There were no significant effects of dietary Se supplementation on the survival, muscle composition or muscle amino acids, whereas regression analysis indicated a positive linear relationship between tissue Se accumulation and dietary Se levels. An enhancement of haematological responses was also observed in cobia fed Se-supplemented diets. In summary, cobia fed lupin-based diets required higher dietary Se supplementation for higher feed utilisation efficiency than previously quantified for the casein-based diet
Continual Learning, Fast and Slow
According to the Complementary Learning Systems (CLS)
theory~\cite{mcclelland1995there} in neuroscience, humans do effective
\emph{continual learning} through two complementary systems: a fast learning
system centered on the hippocampus for rapid learning of the specifics,
individual experiences; and a slow learning system located in the neocortex for
the gradual acquisition of structured knowledge about the environment.
Motivated by this theory, we propose \emph{DualNets} (for Dual Networks), a
general continual learning framework comprising a fast learning system for
supervised learning of pattern-separated representation from specific tasks and
a slow learning system for representation learning of task-agnostic general
representation via Self-Supervised Learning (SSL). DualNets can seamlessly
incorporate both representation types into a holistic framework to facilitate
better continual learning in deep neural networks. Via extensive experiments,
we demonstrate the promising results of DualNets on a wide range of continual
learning protocols, ranging from the standard offline, task-aware setting to
the challenging online, task-free scenario. Notably, on the
CTrL~\cite{veniat2020efficient} benchmark that has unrelated tasks with vastly
different visual images, DualNets can achieve competitive performance with
existing state-of-the-art dynamic architecture
strategies~\cite{ostapenko2021continual}. Furthermore, we conduct comprehensive
ablation studies to validate DualNets efficacy, robustness, and scalability.
Code will be made available at \url{https://github.com/phquang/DualNet}.Comment: arXiv admin note: substantial text overlap with arXiv:2110.0017
Mouse lines with photo-activatable mitochondria to study mitochondrial dynamics
Many pathological states involve dysregulation of mitochondrial fusion, fission, or transport. These dynamic events are usually studied in cells lines because of the challenges in tracking mitochondria in tissues. To investigate mitochondrial dynamics in tissues and disease models, we generated two mouse lines withphoto-activatable mitochondria (PhAM). In the PhAM ^(floxed) line, a mitochondrially localized version of the photo-convertible fluorescent protein Dendra2 (mito-Dendra2) is targeted to the ubiquitously expressed Rosa26 locus, along with an upstream loxP-flanked termination signal. Expression of Cre in PhAM ^(floxed) cells results in bright mito-Dendra2 fluorescence without adverse effects on mitochondrial morphology. When crossed with Cre drivers, the PhAM ^(floxed) line expresses mito-Dendra2 in specific cell types, allowing mitochondria to be tracked even in tissues that have high cell density. In a second line (PhAM ^(excised)), the expression of mito-Dendra2 is ubiquitous, allowing mitochondria to be analyzed in a wide range of live and fixed tissues. By using photo-conversion techniques, we directly measured mitochondrial fusion events in cultured cells as well as tissues such as skeletal muscle. These mouse lines facilitate analysis of mitochondrial dynamics in a wide spectrum of primary cells and tissues, and can be used to examine mitochondria in developmental transitions and disease states
Ytterbium divalency and lattice disorder in near-zero thermal expansion YbGaGe
While near-zero thermal expansion (NZTE) in YbGaGe is sensitive to
stoichiometry and defect concentration, the NZTE mechanism remains elusive. We
present x-ray absorption spectra that show unequivocally that Yb is nearly
divalent in YbGaGe and the valence does not change with temperature or with
nominally 1% B or 5% C impurities, ruling out a valence-fluctuation mechanism.
Moreover, substantial changes occur in the local structure around Yb with B and
C inclusion. Together with inelastic neutron scattering measurements, these
data indicate a strong tendency for the lattice to disorder, providing a
possible explanation for NZTE in YbGaGe.Comment: 4 pages, 4 figure, supplementary inf
Bisphosphonate's and Intermittent Parathyroid Hormone's Effect on Human Spinal Fusion: A Systematic Review of the Literature.
There has been a conscious effort to address osteoporosis in the aging population. As bisphosphonate and intermittent parathyroid hormone (PTH) therapy become more widely prescribed to treat osteoporosis, it is important to understand their effects on other physiologic processes, particularly the impact on spinal fusion. Despite early animal model studies and more recent clinical studies, the impact of these medications on spinal fusion is not fully understood. Previous animal studies suggest that bisphosphonate therapy resulted in inhibition of fusion mass with impeded maturity and an unknown effect on biomechanical strength. Prior animal studies demonstrate an improved fusion rate and fusion mass microstructure with the use of intermittent PTH. The purpose of this study was to determine if bisphosphonates and intermittent PTH treatment have impact on human spinal fusion. A systematic review of the literature published between 1980 and 2015 was conducted using major electronic databases. Studies reporting outcomes of human subjects undergoing 1, 2, or 3-level spinal fusion while receiving bisphosphonates and/or intermittent PTH treatment were included. The results of relevant human studies were analyzed for consensus on the effects of these medications in regards to spinal fusion. There were nine human studies evaluating the impact of these medications on spinal fusion. Improved fusion rates were noted in patients receiving bisphosphonates compared to control groups, and greater fusion rates in patients receiving PTH compared to control groups. Prior studies involving animal models found an improved fusion rate and fusion mass microstructure with the use of intermittent PTH. No significant complications were demonstrated in any study included in the analysis. Bisphosphonate use in humans may not be a deterrent to spinal fusion. Intermittent parathyroid use has shown early promise to increase fusion mass in both animal and human studies but further studies are needed to support routine use
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