Low level methylmercury exposure affects neuropsychological function in adults

BACKGROUND: The neurotoxic effects of methylmercury (MeHg) have been demonstrated in both human and animal studies. Both adult and fetal brains are susceptible to the effects of MeHg toxicity. However, the specific effects of adult exposures have been less well-documented than those of children with prenatal exposures. This is largely because few studies of MeHg exposures in adults have used sensitive neurological endpoints. The present study reports on the results of neuropsychological testing and hair mercury concentrations in adults (>17 yrs) living in fishing communities of Baixada Cuiabana (Mato Grosso) in the Pantanal region of Brazil. METHODS: A cross-sectional study was conducted in six villages on the Cuiaba River. Participants included 129 men and women older than 17 years of age. They were randomly selected in proportion to the age range and number of inhabitants in each village. Questionnaire information was collected on demographic variables, including education, occupation, and residence history. Mercury exposure was determined by analysis of hair using flameless atomic absorption spectrophotometry. The neurocognitive screening battery included tests from the Wechsler Memory Scale and the Wechsler Adult Intelligence Scale, Concentrated Attention Test of the Toulouse-Pierron Factorial Battery, the Manual Ability Subtests of the Tests of Mechanical Ability, and the Profile of Mood States. RESULTS: Mercury exposures in this population were associated with fish consumption. The hair mercury concentration in the 129 subjects ranged from 0.56 to 13.6 μg/g; the mean concentration was 4.2 ± 2.4 micrograms/g and the median was 3.7 μg/g. Hair mercury levels were associated with detectable alterations in performance on tests of fine motor speed and dexterity, and concentration. Some aspects of verbal learning and memory were also disrupted by mercury exposure. The magnitude of the effects increased with hair mercury concentration, consistent with a dose-dependent effect. CONCLUSIONS: This study suggests that adults exposed to MeHg may be at risk for deficits in neurocognitive function. The functions disrupted in adults, namely attention, fine-motor function and verbal memory, are similar to some of those previously reported in children with prenatal exposures

Agricultura Climáticamente Inteligente en El Salvador

The climate-smart agriculture (CSA) concept reflects an ambition to improve the integration of agriculture development and climate responsiveness. It aims to achieve food security and broader development goals under a changing climate and increasing food demand. CSA initiatives sustainably increase productivity, enhance resilience, and reduce/remove greenhouse gases (GHGs), and require planning to address tradeoffs and synergies between these three pillars: productivity, adaptation, and mitigation [1]. The priorities of different countries and stakeholders are reflected to achieve more efficient, effective, and equitable food systems that address challenges in environmental, social, and economic dimensions across productive landscapes. While the concept is new, and still evolving, many of the practices that make up CSA already exist worldwide and are used by farmers to cope with various production risks. Mainstreaming CSA requires critical stocktaking of ongoing and promising practices for the future, and of institutional and financial enablers for CSA adoption. This country profile provides a snapshot of a developing baseline created to initiate discussion, both within countries and globally, about entry points for investing in CSA at scale

Agricultura Climáticamente Inteligente en Sinaloa, México

The climate-smart agriculture (CSA) concept reflects an ambition to improve the integration of agriculture development and climate responsiveness. It aims to achieve food security and broader development goals under a changing climate and increasing food demand. CSA initiatives sustainably increase productivity, enhance resilience, and reduce/remove greenhouse gases (GHGs), and require planning to address tradeoffs and synergies between these three pillars: productivity, adaptation, and mitigation [1]. The priorities of different countries and stakeholders are reflected to achieve more efficient, effective, and equitable food systems that address challenges in environmental, social, and economic dimensions across productive landscapes. While the concept is new, and still evolving, many of the practices that make up CSA already exist worldwide and are used by farmers to cope with various production risks. Mainstreaming CSA requires critical stocktaking of ongoing and promising practices for the future, and of institutional and financial enablers for CSA adoption. This country profile provides a snapshot of a developing baseline created to initiate discussion, both within countries and globally, about entry points for investing in CSA at scale

Efeitos da exposição ocupacional ao mercúrio em trabalhadores de uma indústria de lâmpadas elétricas localizada em Santo Amaro, São Paulo, Brasil Effects of occupational exposure to mercury in workers at a light bulb factory in Santo Amaro, São Paulo, Brazil

O presente estudo teve como objetivo verificar a intoxicação por mercúrio metálico em trabalhadores de uma indústria de lâmpadas elétricas situada em Santo Amaro, São Paulo. Foram realizadas visitas à empresa para verificação do ambiente e das condições de trabalho, além de reuniões com os trabalhadores para uma melhor compreensão acerca do processo produtivo e de suas repercussões na saúde. Foram investigados 91 trabalhadores, dos quais 77 (84,62%) apresentaram quadro de intoxicação crônica. Entre os intoxicados, foram detectadas alterações nos testes neuropsicológicos em 76 (98,70%), alterações neurológicas em 69 (75,82%), alterações no exame clínico em 62 (68,13%) e alterações psiquiátricas em 59 (63,96%).<br>The aim of this research was to study metallic mercury poisoning in workers at a light bulb factory in Santo Amaro, São Paulo (Brazil). Visits were made to the factory to check both the work environment and the working conditions. Meetings with the workers took place in order to better understand the production process and how working conditions affect their health. Of the 91 workers investigated, 77 (84.62%) were chronically poisoned. Among chronically poisoned workers, 76 (98.70%) displayed neuropsychological alterations, 69 (75.82%) suffered from neurological impairments, 62 (68.13%) showed pathological findings under clinical examination, and 59 (63.96%) displayed psychiatric disorders