2,116 research outputs found
Elusive electron-phonon coupling in quantitative analyses of the spectral function
We examine multiple techniques for extracting information from angle-resolved
photoemission spectroscopy (ARPES) data, and test them against simulated
spectral functions for electron-phonon coupling. We find that, in the
low-coupling regime, it is possible to extract self-energy and bare-band
parameters through a self-consistent Kramers-Kronig bare-band fitting routine.
We also show that the effective coupling parameters deduced from the
renormalization of quasiparticle mass, velocity, and spectral weight are
momentum dependent and, in general, distinct from the true microscopic
coupling; the latter is thus not readily accessible in the quasiparticle
dispersion revealed by ARPES.Comment: A high-resolution version can be found at
http://www.physics.ubc.ca/~quantmat/ARPES/PUBLICATIONS/Articles/KKBF.pd
Affinity-based enrichment strategies to assay methyl-CpG binding activity and DNA methylation in early Xenopus embryos
Contains fulltext :
91541.pdf (publisher's version ) (Open Access)9 p
TBP2 is a substitute for TBP in Xenopus oocyte transcription
<p>Abstract</p> <p>Background</p> <p>TATA-box-binding protein 2 (TBP2/TRF3) is a vertebrate-specific paralog of TBP that shares with TBP a highly conserved carboxy-terminal domain and the ability to bind the TATA box. TBP2 is highly expressed in oocytes whereas TBP is more abundant in embryos.</p> <p>Results</p> <p>We find that TBP2 is proteolytically degraded upon meiotic maturation; after germinal vesicle breakdown relatively low levels of TBP2 expression persist. Furthermore, TBP2 localizes to the transcriptionally active loops of lampbrush chromosomes and is recruited to a number of injected promoters in oocyte nuclei. Using an altered binding specificity mutant reporter system we show that TBP2 promotes RNA polymerase II transcription <it>in vivo</it>. Intriguingly, TBP, which in oocytes is undetectable at the protein level, can functionally replace TBP2 when ectopically expressed in oocytes, showing that switching of initiation factors can be driven by changes in their expression. Proteolytic degradation of TBP2 is not required for repression of transcription during meiotic maturation, suggesting a redundant role in this repression or a role in initiation factor switching between oocytes and embryos.</p> <p>Conclusion</p> <p>The expression and transcriptional activity of TBP2 in oocytes show that TBP2 is the predominant initiation factor in oocytes, which is substituted by TBP on a subset of promoters in embryos as a result of proteolytic degradation of TBP2 during meiotic maturation.</p
Bullying and Victimization in Elementary Schools: A Comparison of Bullies, Victims, Bully/Victims, and Uninvolved Preadolescents
Research on bullying and victimization largely rests on univariate analyses and on reports from a single informant. Researchers may thus know too little about the simultaneous effects of various independent and dependent variables, and their research may be biased by shared method variance. The database for
this Dutch study was large (N = 1,065) and rich enough to allow multivariate analysis and multisource information. In addition, the effect of familial vulnerability for internalizing and externalizing disorders was studied. Gender, aggressiveness, isolation, and dislikability were most strongly related to bullying and victimization. Among the many findings that deviated from or enhanced the univariate knowledge
base were that not only victims and bully/victims but bullies as well were disliked and that parenting was unrelated to bullying and victimization once other factors were controlled.
A spectral function tour of electron-phonon coupling outside the Migdal limit
We simulate spectral functions for electron-phonon coupling in a filled band
system - far from the asymptotic limit often assumed where the phonon energy is
very small compared to the Fermi energy in a parabolic band and the Migdal
theorem predicting 1+lambda quasiparticle renormalizations is valid. These
spectral functions are examined over a wide range of parameter space through
techniques often used in angle-resolved photoemission spectroscopy (ARPES).
Analyzing over 1200 simulations we consider variations of the microscopic
coupling strength, phonon energy and dimensionality for two models: a
momentum-independent Holstein model, and momentum-dependent coupling to a
breathing mode phonon. In this limit we find that any `effective coupling',
lambda_eff, inferred from the quasiparticle renormalizations differs from the
microscopic dimensionless coupling characterizing these Hamiltonians, lambda,
and could drastically either over- or under-estimate it depending on the
particular parameters and model. In contrast, we show that perturbation theory
retains good predictive power for low coupling and small momenta, and that the
momentum-dependence of the self-energy can be revealed via the relationship
between velocity renormalization and quasiparticle strength. Additionally we
find that (although not strictly valid) it is often possible to infer the
self-energy and bare electronic structure through a self-consistent
Kramers-Kronig bare-band fitting; and also that through lineshape alone, when
Lorentzian, it is possible to reliably extract the shape of the imaginary part
of a momentum-dependent self-energy without reference to the bare-band.Comment: 15 pages, 11 figures. High resolution available here:
http://www.physics.ubc.ca/~quantmat/ARPES/PUBLICATIONS/Articles/sf_tour.pd
Long-Term Effects of Acceptance and Rejection by Parents and Peers on Educational Attainment:A Study from Pre-Adolescence to Early Adulthood
Acceptance and rejection by parents and peers play an important role in pre-adolescents’ educational outcomes. Prior research focused on either parents or peers, did not encompass effects into adulthood, or considered either acceptance or rejection. This study investigated the relation between parental and peer acceptance and rejection, and their interplay, in pre-adolescence and educational attainment in early adulthood. A sample of 2229 pre-adolescents (M(age) T1 = 11.11, SD = 0.56; 50.7% girls) was followed to early adulthood (M(age) T5 = 22.29, SD = 0.65). Ordinal logistic regression showed that pre-adolescents’ perceived parental acceptance was positively related to educational attainment in early adulthood, whereas peer rejection was negatively related, even when WISC score and socioeconomic status were considered. No interaction effects were found, revealing no “dual-hit effect” of being rejected by parents and peers, no “dual-miss effect” of being accepted by parents and peers, and no effects of acceptance in one context (i.e., parents or peers) buffering the negative effect of rejection in the other context. The findings underscore unique and long-term links of parental acceptance and peer rejection with early adults’ educational attainment, underlining the importance of not only peers but also parents in adolescence. These insights can be used in promoting long-term educational outcomes through relationships with parents and peers
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