49 research outputs found
Influsso di fattori immunologici sull\u27attivita\u27 antitumorale del 4-difenililgliossale nel cancro ascite di ehrlich.
Interferenza esercitata \u27in vitro\u27 dal \u27tween 80\u27 sulla agglutinazione di cellule tumorali.
Sulla sensibilita alla sarcolisina di tumori ascitici di ehrlich in topi \u27vaccinati\u27 con oellule tumorali tratte da animali variamente trattati con la sarcolisina stessa o con altri farmaci antiblastici (tioguanina, actinomicina d).
Ricerche sulla possibilita di indurre alterazioni antigeniche in cellule tumorali mediante trattamento \u27in vivo\u27 con chemioterapici.
The impact of operational risk on performance in supply chains and the moderating role of integration
Purpose: This study aims to empirically investigate the impact of operational risk (i.e. supply, manufacturing and demand risks) on supply chain performance and the moderating role of integration (i.e. supplier, internal and customer integrations) in mitigating the impact of these risks, respectively. Design/methodology/approach: A research framework of hypotheses is tested by structural equation modeling with data collected from the fourth round of the high-performance manufacturing project. Findings: It is revealed that manufacturing and demand risks negatively impact operational performance, and more importantly, internal and customer integrations help to reduce the impact of these two risks. Additionally, the effects of both supply risk and supplier integration are only significant for large firms. Practical implications: Supply chain managers need to appropriately develop the levels of integration to mitigate the adverse impact of operational risk. Originality/value: Operational performance is always threatened by different types of risk that adversely affect the supply, production and demand sides of manufacturing firms. Despite this fact, large-scale data-based empirical research on the impact of operational risk on the performance of supply chains has been scarce. This study aims to fill this literature gap