295 research outputs found

    MinerAlert: an hybrid approach for web mining detection

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    The introduction of new memory-based crypto-mining techniques and the rise of new web technologies like WebAssembly, made the use of browsers for crypto-currencies mining more and more convenient and popular. That, in turn, originated a new form of computer piracy, called cryptojacking, which is rapidly gaining ground on the web. A cryptojacking site exploits its visitors’ hardware resources to secretly mine crypto-currencies. This paper analyzes current web-based cryptojacking detection methods in order to propose a novel hybrid strategy. Current detection methods are found to require either considerable computer administration skills or execution privileges usually not available to common users. In this view, a method, named MinerAlert, has been designed and proposed, aiming at detecting in real-time sites performing cryptojacking. To address the limitations of current methods, the method implementation has been achieved through a browser extension. The present paper describes the method’s details and its implementation. It also reports the experimental results of its utilization, showing its positive performances in terms of ease of use, successful detections and speed

    Acute occlusion of descending thoracic aorta

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    Acute aortic occlusion is a rare but potentially devastating clinical event, which requires a prompt diagnosis and emergency treatment. Only 5 cases of native thoracic aorta acute occlusion have so far been reported with different pathologic causes. The clinical features depend on the level of occlusion. Sometimes the diagnosis could be misinterpreted as a stroke or other diseases of the central nervous system. This could lead to a delay in the diagnosis and revascularization procedure, followed by a morbidity or mortality increase. Open surgery has been considered the first-line approach. This study is of a female patient suffering from acute descending thoracic aorta occlusion undergoing, for the first time to our knowledge, endovascular surgical treatment

    Urgent Carotid Surgery: Is It Still out of Debate?

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    Patients with symptomatic tight carotid stenosis have an increased short-time risk of stroke and an increased long-term risk of ischaemic vascular events compared with the general population. The aim of this study is to assess the safety, efficacy, and limitations of urgent CEA or CAS, in patients with carotid stenosis greater than 70% and clinically characterized by recurrent TIA or brain damage following a stroke (<2.5 cm). This study involved 28 patients divided into two groups. Group A consisted of sixteen patients who had undergone CEA, and group B consisted of twelve patients who had undergone CAS. Primary endpoints were mortality, neurological morbidity (by NIHSS) and postoperative hemorrhagic cerebral conversion, at 30 days. Ten patients (62.5%) of group A experienced an improvement in their initial neurological deficit while in 4 cases (26%) the deficit remained stable. Two cases of neurologic mortality are presented. At 1 month, 9 patients (75%) of group B experienced an improvement in their initial neurological deficit while 3 patients (25%) had a neurological impairment. Urgent or deferred surgical or endovascular treatment have a satisfactory outcome considering the profile in very high-risk patient population. Otherwise in selected patients CEA seems to be preferred to CAS

    The desire of parenthood. Correlation between co-parental interactions and the romantic relationship quality among Italian same-sex couples.

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    In several longitudinal studies, co-parental interactions have been formerly observed during the pregnancy, demonstrating how these interactive dynamics can predict the quality of family interactions with the presence of the baby. Cooperation between the parents during the first year after childbirth is the most predictive factor of the best future adjustment of the baby during the school age and social and affective development.In the last years, research focused on such interactive dynamics recognisable during the process of transition to parenthood; nevertheless, these studies pointed out features regarding a particular type of family defined as \u201ctraditional\u201d, formed by a mother, a father and their biological children. Thanks to the development of the medicine concerning the medical assisted procreation, nowadays parenthood is accessible by gay and lesbian couples as well; gay and lesbian parenting is becoming a reality increasingly relevant also in Italy. Couple satisfaction, co-parental interactions and intuitive parental competences have been evaluated among a sample formed by 45 stable heterosexual, gay and lesbian couples without a child that want to become parents in the future. We used the systemic approach by the prenatal Lausanne Trilogue Play, a semi-naturalistic role-play: this tool involves in a cooperative task the two \u201cparents\u201d and a doll, which represents the child-to-be. Couple satisfaction has been evaluated with the Dyadic Adjustment Scale (DAS Spanier, 1976). Preliminary data suggest that there are no differences between the three groups regarding co-parental intuitive competences and that a higher cohesion between the couple involves a better cooperation between the partners

    Hydrophobic and Oleophobic Coatings Based on Perfluoropolyether/Silica Hybrids by the Sol-Gel Method

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    Glass substrates were spin-coated with a perfluoropolyether oligomer based organic-inorganic hybrid material, and prepared by the sol-gel process. Contact angle analysis and atomic force microscopic analysis were carried out to characterize the surface of the prepared coatings. All systems exhibited strong hydrophobic and oleopophobic characteristics. The wettability behavior was found to be almost independent of both molecular weight and functionality of the fluorinated oligomer. The low values obtained for the contact angle and surface tension indicate that surface segregation of perfluoropolyether segments is likely to take place within the network. On the basis of these results and the high quality of the obtained coatings, these materials could be used as functional coatings to impart water and oleo-repellent characteristics to glasses and other similar substrates

    Light-emitting textiles: Device architectures, working principles, and applications

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    E-textiles represent an emerging technology aiming toward the development of fabric with augmented functionalities, enabling the integration of displays, sensors, and other electronic components into textiles. Healthcare, protective clothing, fashion, and sports are a few examples application areas of e-textiles. Light-emitting textiles can have different applications: Sensing, fashion, visual communication, light therapy, etc. Light emission can be integrated with textiles in different ways: Fabricating light-emitting fibers and planar light-emitting textiles or employing side-emitting polymer optical fibers (POFs) coupled with light-emitting diodes (LEDs). Different kinds of technology have been investigated: Alternating current electroluminescent devices (ACELs), inorganic and organic LEDs, and light-emitting electrochemical cells (LECs). The different device working principles and architectures are discussed in this review, highlighting the most relevant aspects and the possible approaches for their integration with textiles. Regarding POFs, the methodology to obtain side emissions and the critical aspects for their integration into textiles are discussed in this review. The main applications of light-emitting fabrics are illustrated, demonstrating that LEDs, alone or coupled with POFs, represent the most robust technology. On the other hand, OLEDs (Organic LEDs) are very promising for the future of light-emitting fabrics, but some issues still need to be addressed

    How to combine CTA, 99mTc-WBC SPECT/CT, and [18F]FDG PET/CT in patients with suspected abdominal vascular endograft infections?

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    Purpose - We aimed at comparing Tc-99m-HMPAO white blood cells (Tc-99m-WBC) scintigraphy, 18fluorine-fluorodeoxyglucose ([F-18]FDG) positron emission tomography/computed tomography (PET/CT) and CT angiography (CTA) in patients with suspected abdominal vascular graft or endograft infection (VGEI). Moreover, we attempted to define a new visual score for interpreting [F-18]FDG PET/CT scans aiming at increasing its specificity. Methods - We prospectively compared Tc-99m-WBC SPECT/CT, [F-18]FDG PET/CT, and CTA in 26 patients with suspected abdominal VGEI. WBC scans were performed and interpreted according to EANM recommendations. [F-18]FDG PET/CT studies were assessed with both qualitative (Sah's scale and new visual score) and semi-quantitative analyses. CTA images were interpreted according to MAGIC criteria. Microbiology, histopathology or a clinical follow-up of at least 24 months were used to achieve final diagnosis. Results - Eleven out of 26 patients were infected. [F-18]FDG PET/CT showed 100% sensitivity and NPV, with both scoring systems, thus representing an efficient tool to rule out the infection. The use of a more detailed scoring system provided statistically higher specificity compared to the previous Sah's scale (p = 0.049). Tc-99m-WBC SPECT/CT provided statistically higher specificity and PPV than [F-18]FDG PET/CT, regardless the interpretation criteria used and it can be, therefore, used in early post-surgical phases or to confirm or rule out a PET/CT finding. Conclusions - After CTA, patients with suspected late VGEI should perform a [F-18]FDG PET/CT given its high sensitivity and NPV. However, given its lower specificity, positive results should be confirmed with Tc-99m-WBC scintigraphy. The use of a more detailed scoring system reduces the number of Tc-99m-WBC scans needed after [F-18]FDG PET/CT. Nevertheless, in suspected infections within 4 months from surgery, Tc-99m-WBC SPECT/CT should be performed as second exam, due to its high accuracy in differentiating sterile inflammation from infection

    The Fluid-dynamics of endo vascular aneurysm sealing (EVAS) system failure

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    Purpose The main objective of this work is to investigate hemodynamics phenomena occurring in EVAS (Endo Vascular Aneurysm Sealing), to understand if and how they could lead to type 1a endoleaks and following re-intervention. To this aim, methods based on computational fluid mechanics are implemented as a tool for checking the behavior of a specific EVAS configuration, starting from the post-operative conditions. Pressure and velocity fields are detailed and compared, for two configurations of the Nellix, one as attained after correct implantation and the other in pathological conditions, as a consequence of migration or dislocation of endobags. Methods The computational fluid dynamics (CFD) approach is used to simulate the behavior of blood within a segment of the aorta, before and after the abdominal bifurcation. The adopted procedure allows reconstructing the detailed vascular geometry from high-resolution computerized tomography (CT scan) and generating the mesh on which the equations of fluid mechanics are discretized and solved, in order to derive pressure and velocity field during heartbeats. Results The main results are obtained in terms of local velocity fields and wall pressures. Within the endobags, velocities are usually quite regular during the whole cardiac cycle for the post-implanted condition, whereas they are more irregular for the migrated case. The largest differences among the two cases are observed in the shape and location of the recirculation region in the rear part of the aorta and the region between the endobags, with the formation of a gap due to the migration of one or both of the two. In this gap, the pressure fields are highly different among the two conditions, showing pressure peaks and pressure gradients at least four times larger for the migrated case in comparison to the post-implanted condition. Conclusions In this paper, the migration of one or both endobags is supposed to be related to the existing differential pressures acting in the gap formed between the two, which could go on pushing the two branches one away from the other, thus causing aneurysm re-activation and endoleaks. Regions of flow recirculation and low-pressure drops are revealed only in case of endobag migration and in presence of an aneurysm. These regions are supposed to lead to possible plaque formation and atherosclerosis

    Discharge FGF23 level predicts one year outcome in patients admitted with acute heart failure

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    Background: Patients with acute heart failure (AHF) show high levels of fibroblast growth factor-23 (FGF23) on admission. We examined if plasma FGF23 changes during an episode of AHF, and if FGF23 holds prognostic significance in this setting. Methods: Consecutive AHF patients were enrolled. Blood samples were collected on admission and at discharge. Patients were then followed for all-cause death or HF hospitalization. Results: Patients (n = 125; median age 76 years [interquartile interval 71–83], 63% men, left ventricular ejection fraction 35% [25%–56%]) had median admission FGF23 70 ng/L (47–100), N-terminal pro-B-type natriuretic peptide (NT-proBNP) 5844 ng/L (2,503-10,468), high-sensitivity troponin T (hs-TnT) 40 ng/L (25–72), and soluble suppression of tumorigenesis-2 (sST2) 26 ng/mL (17–37). While other biomarkers decreased, FGF23 increased by 15% from admission to discharge (p = 0.033), with a significant correlation with percent changes in estimated glomerular filtration rate (rho = 0.306, p = 0.001). Over a 12-month follow-up, 64 patients (51%) experienced the endpoint. They were more often men, older, with higher systolic pulmonary artery pressure (sPAP), higher NT-proBNP, hs-TnT and discharge FGF23. The best FGF23 cut-off at discharge from receiver operating characteristics analysis was 78 ng/L. Both discharge FGF23 and the 78 ng/L cut-off independently predicted outcome in models including gender, sPAP, age, and 1) admission NT-proBNP, 2) discharge NT-proBNP, 3) admission NT-proBNP and hs-TnT, 4) discharge NT-proBNP and hs-TnT. The 78 ng/L cut-off also refined risk reclassification. Conclusions: During an AHF episode, FGF23 increases from admission to discharge, and patients with higher discharge FGF23 have a higher risk of worse outcome
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