1,278 research outputs found

    Nature and origin of secondary mineral coatings on volcanic rocks of the Black Mountain, Stonewall Mountain, and Kane Springs Wash volcanic centers, southern, Nevada

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    The following subject areas are covered: (1) genetic, spectral, and LANDSAT Thematic Mapper imagery relationship between desert varnish and tertiary volcanic host rocks, southern Nevada; (2) reconnaissance geologic mapping of the Kane Springs Wash Volcanic Center, Lincoln County, Nevada, using multispectral thermal infrared imagery; (3) interregional comparisons of desert varnish; and (4) airborne scanner (GERIS) imagery of the Kane Springs Wash Volcanic Center, Lincoln County, Nevada

    Kitchen-Sink Enlightenment: A Review of “Grace for Amateurs”

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    Excerpt: Here’s an honest admission: Several times while reading Lily Burana’s new book Grace for Amateurs: Field Notes on a Journey Back to Faith, I consulted the copyright page, confirming again that Grace for Amateurs was really published by Thomas Nelson, the notoriously evangelical (and, in my mind, notoriously traditional) press. After all, it wasn’t that long ago that Thomas Nelson asked another writer to remove the word “vagina” from her book, well aware that Christian readers would balk at language so closely associated with women and S-E-X. Would this same publisher be willing to support a memoir as edgy and progressive as Burana’s

    Nature and origin of mineral coatings on volcanic rocks of the Black Mountain, Stonewall Mountain, and Kane Springs Wash volcanic centers, Southern Nevada

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    Comparative lab spectra and Thematic Mapper imagery investigations at 3 Tertiary calderas in southern Nevada indicate that desert varnish is absorbant relative to underlying host rocks below about 0.7 to 1.3 microns, depending on mafic affinity of the sample, but less absorbant than mafic host rocks at higher wavelengths. Desert varnish occurs chiefly as thin impregnating films. Distribution of significant varnish accumulations is sparse and localized, occurring chiefly in surface recesses. These relationships result in the longer wavelength bands and high 5/2 values over felsic units with extensive desert varnish coatings. These lithologic, petrochemical, and desert varnish controlled spectral responses lead to characteristic TM band relationships which tend to correlate with conventionally mappable geologic formations. The concept of a Rock-Varnish Index (RVI) is introduced to help distinguish rocks with a potentially detectable varnish. Felsic rocks have a high RVI, and those with extensive desert varnish behave differently, spectrally, from those without extensive varnish. The spectrally distinctive volcanic formations at Stonewall Mountain provide excellent statistical class segregation on supervised classification images. A binary decision rule flow-diagram is presented to aid TM imagery analysis over volcanic terrane in semi-arid environments

    The dual role of the X-linked FoxP3 gene in human cancers

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    The FoxP3 (forkhead box P3) gene is an X-linked gene that is submitted to inactivation. It is an essential transcription factor in CD4(+)CD25(+)FoxP3 regulatory T cells, which are therapeutic targets in disseminated cutaneous melanoma. Moreover, FoxP3 is an important tumor suppressor gene in carcinomas and has putative cancer suppressor gene function in cutaneous melanoma as well. Therefore understanding the structure and function of the FoxP3 gene is crucial to gaining insight into the biology of melanoma to better develop immunotherapeutics and future therapeutic strategies

    Nature and origin of mineral coatings on volcanic rocks of the Black Mountain, Stonewall Mountain, and Kane Springs, Wash volcanic centers, Southern Nevada

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    LANDSAT Thematic Mapper imagery was evaluated over 3 Tertiary calderas in southern Nevada. Each volcanic center derived from a highly evolved silici magmatic system represented today by well exposed diverse lithologies. Distinctive imagery contrast between some of the late ash flows and earlier units follows from the high relative reflectance in longer wavelength bands (bands 5 and 7) of the former. Enhancement techniques provide color composite images which highlight some of the units in remarkable color contrast. Inasmuch as coatings on the tuffs are incompletely developed and apparently largely dependent spectrally on rock properties independent of petrochemistry, it is felt that the distinctive imagery characteristics are more a function of primary lithologic or petrochemical properties. Any given outcrop is backdrop for a variety of cover types, of which coatings, at various stages of maturity, are one. Petrographic and X-ray diffraction analysis of the outer air-interface zone of coatings reveal they are composed chiefly of amorphous compounds, probably with varying proportions of iron and manganese. Observations support an origin for some outer (air-interface) coating constituents exogenous to the underlying host

    Nature and origin of mineral coatings on volcanic rocks of the Black Mountain, Stonewall Mountain and Kane Springs Wash volcanic centers, southern Nevada

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    Surface coatings on volcanic rock assemblages that occur at select tertiary volcanic centers in southern Nevada were investigated using LANDSAT 5 Thematic Mapper imagery. Three project sites comprise the subject of this study: the Kane Springs Wash, Black Mountain, and Stonewall Mountain volcanic centers. LANDSAT 5 TM work scenes selected for each area are outlined along with local area geology. The nature and composition of surface coatings on the rock types within the subproject areas are determined, along with the origin of the coatings and their genetic link to host rocks, geologic interpretations are related to remote sensing units discriminated on TM imagery. Image processing was done using an ESL VAX/IDIMS image processing system, field sampling, and observation. Aerial photographs were acquired to facilitate location on the ground and to aid stratigraphic differentiation

    Nafld epidemiology, emerging pharmacotherapy, liver transplantation implications and the trends in the United States

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    © 2020 Authors. Nonalcoholic fatty liver disease (NAFLD) is a hepatic mani-festation of metabolic syndrome. The spread of obesity worldwide in pandemic proportions has led to a rapid rise of NAFLD in developed and developing countries alike. There are no approved pharmacological agents to treat steatohepatitis or advanced fibrosis but obeticholic acid recently has shown some promise in phase III trial. Currently, NAFLD is the number one etiology for simultaneous liver and kidney transplantation in the USA, second most common indication for liver transplantation (LT) and projected to become number one very soon. LT for NAFLD poses unique challenges, as these patients are generally older, obese and more likely to have a number of metabolic risk factors. Bariatric surgery is an option and can be considered if a structured weight loss program does not achieve the sustained weight loss goal. Comprehensive cardiovascular risk assessment and aggres-sive management of comorbid conditions are crucial in the LT evaluation process to improve post-transplant survival. Re-current nonalcoholic steatohepatitis after LT is not uncom-mon, and thus warrants primary and secondary prevention strategies through a multidisciplinary approach. Prevalence of NAFLD in a donor population is a unique and growing concern that limits the access to quality liver grafts
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